Annette Dolphin obituary Other lives: Neuroscientist whose research showed how individual molecules can affect neurological disorders

Obituary of Annette Dolphin @annieneuro.bsky.social written by her sister in The Guardian. www.theguardian.com/science/2026...

Development of the fluorescent probe CenSpark for labeling centrioles and cilia - Nature Chemical Biology CenSpark is a dual-ligand fluorescent probe binding simultaneously inner and outer microtubule sites, a configuration unique to doublet and triplet microtubules, enabling selective live imaging of cen...

Very cool probe to label doublet MTs and therefore centrioles across different species and set ups (from live imaging, STED and expansion)!😍

www.nature.com/articles/s41...

Four UW researchers named AAAS Fellows Four UW researchers named AAAS Fellows

Nice of @thedailyuw.bsky.social to interview me and @bethbuffalo.bsky.social about becoming AAAS Fellows! www.dailyuw.com/article/fe9d...

Whattttt???? Okay, that’s definitely new.

Thank you for coming!!! It was a joy to host you!!! ❤️🦔

New preprint from the lab!

How do tissue shapes influence cell fate decisions?

By manipulating brain organoid geometry, we show that lumen rounding directs apical progenitor division mode and promotes the emergence of basal progenitors.

www.biorxiv.org/content/10.6...

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Another paper from our awesome lab out today @nature.com. Led by 🌟 PD Jihye Yeon with fantastic collaborators. We show how an ionotropic receptor (related to insect sensory IRs) in a single pharyngeal enteric neuron senses ingested salts and protects the worm from high salt stress.
rdcu.be/fbd4a

Donate to Honoring Allison’s Life with Love and Support, organized by Hana El-samad Allison McKenzie Williams, a cherished friend and member of the UCSF commu… Hana El-samad needs your support for Honoring Allison’s Life with Love and Support

In those small interactions that last with you. Allison was very kind to me during a visit at UCSF. Read more about the science from her lab here and give if you can: williamslab.ucsf.edu

gofund.me/b1719874d

I have no SoundCloud to share but Ben's autobiography is available at MIT press mitpress.mit.edu/author/ben-b... or I can share the SFN version if you DM me. Also, a good egg is working on a feature film about Ben if you'd like to help share his story more broadly: askthequestionmovie.com

2026 Waddington Medal Winner - James Briscoe - BSDB - British Society for Developmental Biology We are very pleased to announce that this year’s Waddington medal winner is James Briscoe. His fundamental discoveries have helped shape our understanding of of how morphogens work, and he has played ...

Honoured and overwhelmed to receive the 2026 Waddington Medal. Science is a team effort, and I've been fortunate to work alongside exceptional people asking hard questions. Thank you to the BSDB and to everyone who has been part of the journey.

bsdb.org/2026/03/24/2...

Congratulations!!!! 🎉🎉🎉

🧵 New preprint led by @bingbrunton.bsky.social, @elliottabe.bsky.social, @lawrencehu.bsky.social

We gave a worm brain control of a fly body and it walked

What did we learn? Nothing, other than deep reinforcement learning is effective

We call it the digital sphinx

www.biorxiv.org/content/10.6...

I’m so sorry. Incredibly heartbreaking.

Michael Bishop, Nobel Prize in Physiology or Medicine 1989: Official Lecture YouTube video by Nobel Prize

Very sad to hear of the passing today of our UCSF colleague Mike Bishop at the age of 90. A legendary and inspiring figure. He also led UCSF as Chancellor. Have a listen to his Nobel lecture. youtube.com/watch?v=CDv7...

Our @statnews.com survey of NIH-funded researchers drew nearly 1,000 responses from 45 states (plus DC and Puerto Rico). Here's a short thread on 5 scientists' whose labs and lives have been deeply impacted by federal policies 🧵

NIGMS is signed onto the F31 NOFO. grants.nih.gov/grants/guide...

A banner displaying the Health Sciences 2026 Summer Grant Writing Course as the title. Underneath it says to apply by March 17th at gwc.ucsd.edu. The bottom part of the banner is a infographic of alumni outcomes for the course and says that the alumni outcomes are highly successful. There was a 49% increase in respondents' confidence to fund a study, 96% of respondents' submitted at least one grant, and 79% of respondents have least at one grant funded. These evaluation outcomes are from 2017-2021 and within 2 years of post course completion.

🚨Applications are open for the 2026 Summer Grant Writing Course! Jr. faculty will develop a complete NIH proposal using feedback from NIH-funded senior faculty in this highly successful & evidence-based, 9-session online course.

👉 Learn more & apply @ gwc.ucsd.edu
⏰ Deadline: March 17 @ 11:59 PM

The figure shows staining of mouse embryos with X-gal to highlight Ttc21b in whole-mount embryos (panels A-D,H) or after sectioning (panels E-G,I-N). Boxed areas in panel E are shown magnified in panels F and G, boxed areas in panels I and L are shown magnified in panels J and M. Arrows indicate specific areas of lacZ expression.

Rebekah Niewoehner, Rolf Stottmann & co found that pathogenic Ttc21b variants, the primary #cilia gene, contribute to primary #microcephaly, with homozygous #mouse mutants showing severe #microcephaly due to impaired neural progenitor proliferation and differentiation.

Read doi.org/10.1242/dmm....

😂😂😂 I just did this yesterday. Like… maybe I missed an email???

I had no idea. So cool!!! Thanks for sharing! ⭐️⭐️⭐️

Absolutely love the exploratorium!!! Hope you have a great visit.

How does a cell move when it carries cargo larger than its own organelles?

Excited to share our findings: cells can mechanoadapt their force architecture to move oversized cargo

Watch the bulky parasite (red) within an immune cell squeezing through a tiny pore

www.biorxiv.org/content/10.1...

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In class today, we reread this nice article about scientific community doi.org/10.1073/pnas.... We talked about the ways in which the #C.elegans community helps research move forward and reach other scientists.

Gene regulatory networks: from correlative models to causal explanations Nature Reviews Genetics - In this Perspective, Maizels and Briscoe discuss the limitations of current models of gene regulatory networks and outline solutions to harness data abundance without...

New Perspective form Rory Maizels & me: "Gene regulatory networks: from correlative models to causal explanations"

Gene regulatory networks are supposed to give us mechanistic explanations of development, so why are we drowning in 'hairballs' of statistical correlations?

rdcu.be/e7zx7

😂😂😂

🎉🎉🎉

Another preprint is out from the Neal Lab! 🎉

Excited to share the first systematic side-by-side comparison of ERAD Derlin paralogs, revealing distinct cellular functions for Derlin-1, Derlin-2, and Derlin-3.
www.biorxiv.org/content/10.6...

Congrats!!!!

Fred Hutchinson Cancer Center Fred Hutch is dedicated to the elimination of cancer and related diseases as causes of human suffering and death.

My awesome colleague, @yarimura.bsky.social, is recruiting a postdoc to start at the end of 2026 or early 2027! His lab uses cryo-EM to uncover structural basis of key chromatin events using native complexes isolated from human cells or Xenopus egg extracts!

careers-fhcrc.icims.com/jobs/30706/p...

Some shit is about to go down with NIH study sections, friends. Keep your eyes peeled for change that may affect your grant submissions.