At last: a Stonehenge story that is exactly what it says The new Antiquity has a paper by Simon Banton, Mark Bowde...

At last: a Stonehenge story that is exactly what it says: Simon Banton, Tim Daw and Mark Bowden (left to right... http://bit.ly/1qTYhXe

Marvellous artefact that formed part of the front of a canoe. Made of wood, the crocodile eyes are represented by fine china cups. Seen at the Museum of Anthropology in Cambridge. #happysaturday

Congratulations 🎊 👏 💐 🥳

👉 @same18-bcn.bsky.social @ramalok.bsky.social
@microbiomacsic.bsky.social @ice-csic.bsky.social @soniagr.bsky.social @itq-upvcsic.bsky.social @sribo.bsky.social @sebbm.bsky.social y @esanchezsanchez.bsky.social
👋👋 ¡Gracias por seguirnos! 👋👋
#cienciaparalaagricultura

Long-read RNA sequencing atlas of human microglia isoforms elucidates disease-associated genetic regulation of splicing - Nature Genetics This isoform-centric microglia genomic atlas includes 35,879 novel human microglia isoforms identified by long-read RNA sequencing. A multi-ancestry quantitative trait locus meta-analysis of known and...

Ecstatic to see our paper "Long-read RNA sequencing atlas of human microglia isoforms elucidates disease-associated genetic regulation of splicing" now published in @naturegenet.bsky.social with @trajnp.bsky.social and @panosroussos.bsky.social @sinaibrain.bsky.social www.nature.com/articles/s41...

Extraordinary man.

If you can, donate blood 🩸 it takes 30 mins and saves lives 🙏🏻

Thrilled to see our Perspective on long-read transcriptomics Published in Advance in @genomeresearch.bsky.social, with #AdamFrankish and @carolinamonzo.bsky.social. We discuss the opportunities and challenges of LRS to uncover Transcript Divergence and for Genome Annotation. tinyurl.com/bdeteu4j

This was so powerful - few of us can imagine the reality of having a family devastated by familial FTD - and the response of Jordan/Cian to their own risk is incredibly inspiring. Find them in instagram/TikTok as the FTD Brothers and follow their story…!

Yesterday’s Cambridge RNA Club was a blast! Despite a small crowd, we had great science, lively discussions and, of course… pizza! Quality over quantity, right? Huge thanks to @vanessaloi.bsky.social @soniagr.bsky.social & sponsors for making it a fantastic session! See you at the next one!

🎤 Excited to learn how RNA splicing is linked to Alzheimer’s? @soniagr.bsky.social (UK Dementia Research Institute) will unveil insights from single-nucleus RNA-seq at the Cambridge RNA Club!
Join us for cutting-edge science & stay for networking 🍕on 20th Feb at 17h in @cambiochem.bsky.social

📢 Reminder! This Thursday at 17:00, join us for an exciting session of Cambridge RNA Club with @soniagr.bsky.social and @vanessaloi.bsky.social
📍 Sanger building @CamBiochem
🍕 Networking after with pizza, snacks & drinks!
Sponsored by @rnasociety.bsky.social , Lexogen, NEB & 2BScientific

It is really cold out there! I would rather prefer to stay warm and cozy at home. Happy #caturday folks!

The magnificent Magna Carta, a royal charter of rights agreed to by King John of England on 15 June 1215. It limited the rights of the King by declaring him to be subject to the rule of law. It provided the foundation for individual rights. On display at the British Library #magnacarta

Happy #Caturday folks!

Wow, I love it!

El mural que homenajea a la investigadora Ana Conesa en Benimaclet La investigadora Ana Conesa ya tiene en su barrio, Benimaclet, un mural que la homenajea. Lo ha creado Clara Gómez dentro del proyecto ‘Dones de ciència’.

Precioso reportaje sobre el mural que la pintora Clara Gomez Campos me ha pintado en mi barrio, Benimaclet.
disfrutabenimaclet.com/2025/01/27/e...

6) This has been an extensive collaborative team effort! Thanks to @jwbrenton.bsky.social MelissaGrant-Peters ZhongboChen EmilKGustavson ReginaHReynolds @lcolladotor.bsky.social
AineFairbrother-Browne and many more from our lab (RytenLab rytenlab.xn--com)-876aaa40307gka16qcac854l97a7k

5) Overall, this in-depth characterisation of splicing accuracy can expand our understanding of the role of inaccuracies in ageing and neurodegenerative disorders.

4/ Key findings 🔑 3) We observe a genome-wide increase in splicing inaccuracies in samples affected with Alzheimer’s disease compared to neurologically normal individuals. 🧠

3) Key findings 🔑 2) We find that age is positively correlated with a global decline in splicing fidelity, mostly affecting genes implicated in neurodegenerative diseases. 💆‍♂️ #ageing #splicingnoise #splicingaccuracy #neurodegeneration

2) Key findings 🔑1) We show that splicing inaccuracies occur at different rates across introns and tissues and are affected by the abundance of core components of the spliceosome assembly and its regulators. #RNAbindingProteins #NMDpathway

1) Methods📝 We investigate splicing accuracy using short-read RNA-sequencing data from >14k control samples and 40 human body sites, focusing on split reads that partially map to known transcripts in the reference annotation.

Splicing accuracy varies across human introns, tissues, age and disease - Nature Communications Inaccuracies in RNA splicing may play a significant role in aging and disease. Here, the authors present a comprehensive characterization of splicing accuracy across over 14,000 human samples, offerin...

New in @naturecomms.bsky.social: I'm thrilled to share with you our latest work that applies #srRNAseq to understand splicing accuracy across human introns, tissues and in the context of ageing and neurodegeneration www.nature.com/articles/s41...

#dinkydoors Miniature sculpture (with doors), lovingly made and hidden just out of plain sight around Cambridge. This one can be seen in Downing Street Cambridge, which mimicks the real and famous one in London. There are many of them, and they represent cute petite portals into other worlds :)

I can not comprehend the size and scale of the observable universe: roughly 2 trillion galaxies, ~400 billion stars per galaxy (considering the size of the Milky Way). This is just the piece we can observe given the speed of light (it takes over 100,000 years to cross our galaxy! 🤯

Hello world

Great symposium today with The British Neuroscience Association🧠and hosted by AstraZeneca @astrazeneca.bsky.social at The Discovery Centre. Amazing talks and speakers, with engaging panel discussion in the 'quest for new medicines to slow the progression of disability in neurodegenerative disorders'

Here are some free/open-source sites for the preparation of scientific illustrations, including icon libraries: bioicons.com, scidraw.io, bioart.niaid.nih.gov, inkscape.org, biogdp.com, reactome.org/icon-lib

Sunday walk 🍂 #cambridge #autumn

Amazed by evolution and the creatures that preceded us, this one is called Megaloceros giganteus (aka 'Giant Irish Elk'), although they were not elk but deer and not specifically Irish either as their fossil remains have been found in EU and Asia 🤷‍♀️ but surely giantic (their antlers were 10ft wide!)🫣