Folks have been asking me which of the currently available UK #COVID vaccines are best, given that an older flavour, "KP2" is being given free on the NHS to the twelve or so people that remain eligible (😜🙄), whilst the newer "LP8.1" is available privately...

I'll do my best...

It feels ironic that this news comes 41 years and a day after my father-in-law died. He donated his brain for Huntington’s disease research, as did my husband 19 years ago. I often wonder how much such donations have contributed to advances in research 🤔

Gene therapy appears to slow Huntington’s disease progression A global clinical trial for a new Huntington’s disease treatment has posted positive results today, announced by trial sponsor uniQure and UCL scientists.

www.ucl.ac.uk/news/2025/se...

From @hdbuzzfeed.bsky.social
en.hdbuzz.net/the-first-do...

Huntington’s disease treated successfully for first time in UK gene therapy trial Surgical procedure to treat devastating illness slowed progress of disease by 75% in patients after three years

From @theguardian.com "Huntington’s disease treated successfully for first time in UK gene therapy trial"
www.theguardian.com/science/2025...

A positive development from uniQure

From the Huntington's Disease Association @hda.org.uk:
www.hda.org.uk/news/a-posit...

uniQure Announces Positive Topline Results from Pivotal Phase I/II Study of AMT-130 in Patients with Huntington’s Disease ~ Pivotal study met primary endpoint; high-dose AMT-130 demonstrated statistically significant 75% disease slowing at 36 months as measured by cUHDRS...

uniQure Announces Positive Topline Results from Pivotal Phase I/II Study of AMT-130 in Patients with Huntington’s Disease
www.globenewswire.com/news-release...

Huntington's disease successfully treated for first time One of the most devastating diseases finally has a treatment that can slow its progression and transform lives, tearful doctors tell BBC.

153 years after Dr George Huntington’s paper “On Chorea” was published describing the disease now known as Huntington’s disease, and 32 years after the discovery of the huntingtin gene, I’m thrilled beyond description to read “Huntington's disease successfully treated for first time”

The figure of a person within a shattered shield with the text: CLINICALLY VULNERABLE PEOPLE AT RISK #KeepCovidBoosters SAVE LIVES followed by the Clinically Vulnerable Families Organisation's logo

Screenshot of the "Fund NHS COVID boosters for Clinically Vulnerable people – keep covid boosters" Petition showing 2,046 signatures to date

#KeepCovidBoosters and Save Lives
Please sign the petition:
➡️ petition.parliament.uk/petitions/73... ⬅️
Please share to encourage further support
Thanks in anticipation 😊

Congratulations 🎉 Totally agree regarding the inspirational Wexler family and am honoured to have hugged Nancy. Please accept a virtual hug from me for your achievements 🤗

Diabetics at risk Image of drop of insulin (light blue) within a shattered shield #KeepCovidBoosters SAVE LIVES Clinically Vulnerable Families logo

🚨 Diabetics at risk 🚨

Type 1, and 2 diabetes account for 1 in 5 Covid deaths. Yet the UK govt plans to end NHS boosters for many vulnerable groups including diabetics.

❌ Risks have NOT gone
💰 It costs £100+ privately

✍️ Petition next, then ✨NEW blog
#KeepCovidBoosters

A poster with both the UK Government and the Clinically Vulnerable Families Organisation logos stating: SIGN OUR UK GOVERNMENT PETITION KEEP COVID BOOSTERS FOR CLINICALLY VULNERABLE PEOPLE SAVE LIVES

A graphic of a drop of insulin surrounded by a fractured shield stating: DIABETICS AT RISK #KeepCovidBoosters SAVE LIVES followed by the Clinically Vulnerable Families Organisation's logo

#KeepCovidBoosters and Save Lives
Please sign the petition:
➡️ petition.parliament.uk/petitions/73... ⬅️
Please share to encourage further support
Thanks in anticipation 😊

Screenshot of the Petition “Fund NHS COVID boosters for Clinically Vulnerable people – keep covid boosters” showing 1,118 signatures so far

Screenshot of the “Fund NHS COVID boosters for Clinically Vulnerable people – keep covid boosters” petition’s map showing the location of the 1,118 signatories to date

#KeepCovidBoosters and Save Lives
Please sign the petition:
petition.parliament.uk/petitions/73...
Please share to encourage further support 😊

Protect Clinically Vulnerable People #KeepCovidBoosters From autumn 2025, millions of people at higher risk from COVID-19 will be denied an NHS COVID booster. This includes many who were once officially told to shield because of their risks. Vaccines wil...

A blog explaining why Clinically Vulnerable Families (CVF) has launched a UK Government petition to #KeepCovidBoosters www.clinicallyvulnerable.org/post/keep-nh...
Please sign the petition and share to encourage further support:
petition.parliament.uk/petitions/73... Thank you!

A graphic of a beating heart surrounded by a shield stating: HEART PATIENTS AT RISK #KeepCovidBoosters SAVE LIVES followed by the Clinically Vulnerable Families Organisation's logo

A poster with both the UK Government and the Clinically Vulnerable Families Organisation logos stating: SIGN OUR UK GOVERNMENT PETITION KEEP COVID BOOSTERS FOR CLINICALLY VULNERABLE PEOPLE SAVE LIVES

#KeepCovidBoosters and Save Lives
Please sign the petition:
petition.parliament.uk/petitions/73...

A poster with both the UK Government and Clinically Vulnerable Families Organisation logos stating: SIGN OUR UK GOVERNMENT PETITION KEEP COVID BOOSTERS FOR CLINICALLY VULNERABLE PEOPLE SAVE LIVES

Please sign the petition:
petition.parliament.uk/petitions/73...
(UK residents, including children and UK ex-pats, are eligible - and the same email can be used for more than one person if needed)
#COVID19 #CEV #CV #COVID19Booster #Petition

30M users 1B posts
🤝
bluesky milestone
achieved this week

As the ITV schedule states "ITV News Regional" at 6pm, will this be available nation wide?

On the 5-year anniversary since the first COVID-19 cases in the UK, Dr Heidi Baseler (Psychology Department, University of York) talks with ITV, airing on Friday, 31st January 2025 at 6pm about research on effects of long COVID on working memory and other brain changes.

On the 5-year anniversary since the first COVID-19 cases in the UK, Dr Heidi Baseler (Psychology Department, University of York) talks with ITV, airing on Friday, 31st January 2025 at 6pm about research on effects of long COVID on working memory and other brain changes.

Sara Sharif family court judges named after appeal Judges who oversaw Family Court hearings before Sara was murdered have been named after an appeal by the BBC and others.

#SaraSharif Sara Sharif's family court judges named ⬇️

Andy Bunday on #Trump #RFKJrHearing #RFKJr – political cartoon gallery in London original-political-cartoon.com

❤️ 👏 🦋 👍 Sane @sane.org.uk has quit X 👍 🦋 👏 ❤️

❤️ 👏 🦋 👍 Mind @mindcharity.bsky.social has quit X 👍 🦋 👏 ❤️

EU medicines agency quits X, moves to Bluesky The European Medicines Agency (EMA) said on Monday it would no longer post on X and would use rival Bluesky instead, becoming the latest organisation to quit a social media platform that some have criticised for its content.

❤️ 👏 🦋 👍 AMSTERDAM, Jan 27 (Reuters) - The European Medicines Agency (EMA) said on Monday it would no longer post on X and would use rival Bluesky instead, becoming the latest organisation to quit a social media platform that some have criticised for its content 👍 🦋 👏 ❤️

Charity stops using Captain Sir Tom Moore's name The Bedfordshire based charity is now known as The 1189808 Foundation.

Charity stops using Captain Sir Tom Moore's name
"The commission confirmed the charity has applied to change its name on the Register of Charities after documents submitted to Companies House, external showed it has been renamed as The 1189808 Foundation"
www.bbc.co.uk/news/article...

Captain Sir Tom Moore's name dropped from foundation set up in his name following scathing report Late last year a report found there had been "repeated" misconduct and mismanagement on the part of Sir Tom's daughter and her husband in their running of the foundation.

Captain Sir Tom Moore's name dropped from foundation set up in his name following scathing report
"Late last year a report found there had been "repeated" misconduct and mismanagement on the part of Sir Tom's daughter and her husband in their running of the foundation"
news.sky.com/story/captai...

Captain Sir Tom Moore's name dropped from foundation set up in his honour
"The Captain Tom Foundation is now known as the 1189808 Foundation, reflecting the organisation’s charity number" ⬇️
www.itv.com/news/anglia/...

X refuses to remove stabbing video watched by Southport killer Axel Rudakubana was able to view Australian clip before murdering three young children despite pleas from authorities

X refuses to remove stabbing video watched by Southport killer
Axel Rudakubana was able to view Australian clip before murdering three young children despite pleas from authorities
⬇️

Sara Sharif: Appeal won to name girl's family court judges A decision not to name judges in historical family court cases about Sara's care has been appealed.

#SaraSharif Appeal won to name Sara Sharif's family court judges ⬇️

Long somatic DNA-repeat expansion drives neurodegeneration in Huntington’s disease Single-cell measurement of the Huntington’s disease-causing CAG repeat reveals that somatic expansion of this repeat drives pathological changes in neurons, providing insights into disease progression...

Original scientific article: "Long somatic DNA-repeat expansion drives neurodegeneration in Huntington’s disease" (open access) ⬇️