Genetic removal of Nlrp3 protects against age-related and R345W Efemp1-induced basal laminar deposit formation - Cell Death & Disease Cell Death & Disease - Genetic removal of Nlrp3 protects against age-related and R345W Efemp1-induced basal laminar deposit formation

Sharing our latest work on #AMD and how dampening #Nlrp3 #inflammasome signaling protects against #BLamD retinal pathology in multiple mouse models.

www.nature.com/articles/s41...

Select azo compounds post-translationally modulate HTRA1 abundance and activity potentially through interactions at the trimer interface www.biorxiv.org/content/10.1101/2025.05....

Happening now @arvoinfo.bsky.social 2025: Steffi Daniel presenting on an in vitro RPE mineralization model to study the early stages of #drusen formation in #AMD. #ARVO2025. Poster B0079