Overall survival with relacorilant and nab-paclitaxel in patients with platinum-resistant ovarian cancer (ROSELLA): a phase 3 randomised controlled trial The addition of relacorilant to nab-paclitaxel led to significantly longer overall survival in patients with platinum-resistant ovarian cancer, without the need for biomarker selection. The findings s...

Overall survival with relacorilant and nab-paclitaxel in patients with platinum-resistant #OvarianCancer (ROSELLA): a phase 3 randomised controlled trial. www.thelancet.com/journals/lan...

Systemic Treatment of Thyroid Cancer: ASCO Guideline ASCO Guidelines provide recommendations with comprehensive review and analyses of the relevant literature for each recommendation, following the guideline development process as outlined in the ASCO Guidelines Methodology Manual. ASCO Guidelines follow ...

Systemic Treatment of Thyroid Cancer: ASCO Guideline ascopubs.org/doi/10.1200/... #Cancer

Efficacy and safety of darolutamide in combination with androgen deprivation therapy and docetaxel in European patients from the phase 3 ARASENS trial www.ejcancer.com/article/S095... #Cancer

Medial retropharyngeal nodal region sparing radiotherapy in nasopharyngeal carcinoma: five year analysis of open label, non-inferiority, multicentre, randomised phase 3 trial www.bmj.com/content/392/... #Cancer

Uveal melanoma: ESMO–EURACAN Clinical Practice Guideline for diagnosis, treatment and follow-up www.esmoopen.com/article/S205... #CAncer

Datopotamab deruxtecan in patients with untreated, advanced triple-negative breast cancer (TROPION-Breast02) www.annalsofoncology.org/article/S092... #Cancer

Anti-infective vaccination strategies in patients with haematological malignancies or solid tumours: updated guideline of the Infectious Diseases Working Party of the German Society for Hematology and Medical Oncology Vaccine-preventable infections remain a major cause of morbidity and mortality in patients with cancer. The updated guideline for anti-infective vaccination strategies in patients with cancer of the German Society of Hematology and Medical Oncology Infectious Diseases Working Group was developed by a guideline panel of experts in internal medicine, haematology, medical oncology, and infectious diseases. For previously covered vaccinations, we included all publications in patients with cancer starting from 2017, as this was the data cutoff for the previous guideline, and for newly included vaccines all publications were reviewed.

Anti-infective vaccination strategies in patients with haematological malignancies or solid tumours: updated guideline of the Infectious Diseases Working Party of the German Society for Hematology & Medical Oncology www.thelancet.com/journals/lan... #Cancer

Pain and health-related quality-of-life outcomes with darolutamide in metastatic hormone-sensitive prostate cancer (ARANOTE): secondary and exploratory analyses of a multicentre, randomised, placebo-controlled, phase 3 trial Along with the known survival benefits, the clinically meaningful delays in pain progression and time to deterioration of overall wellbeing support consideration of darolutamide plus ADT as a standard-of-care treatment option in patients with mHSPC.

Pain and health-related quality-of-life outcomes with darolutamide in metastatic hormone-sensitive #prostatecancer (ARANOTE): secondary and exploratory analyses www.thelancet.com/journals/lan... #Cancer

Global burden of cancer in children and adolescents aged 0–19 years, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023 Global childhood cancer burden remains a substantial contributor to global childhood disease and cancer burden and is disproportionately weighted towards resource-limited settings. The estimation of additional cancer types relevant in childhood provides a step towards alignment with WHO GICC targets. Efforts to decrease global childhood cancer burden should focus on addressing the inequities in burden worldwide and support comprehensive improvements along the childhood cancer diagnosis and care continuum.

Global burden of cancer in children and adolescents aged 0–19 years, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023 www.thelancet.com/journals/lan... #Cancer

Progress towards the WHO Global Initiative for Childhood Cancer target of 60% 5-year survival for all childhood cancers combined, 1990–2019 (CONCORD-4) www.thelancet.com/journals/lan... #Cancer

UK real-world evidence on pembrolizumab and neoadjuvant chemotherapy for early-stage triple-negative #breastcancer www.sciencedirect.com/science/arti... @velindrecc.bsky.social #Cancer

Visualization of Multi-indication Randomized Control Trial Evidence to Support Decision Making in Oncology: A Case Study on Bevacizumab journals.sagepub.com/doi/10.1177/... @velindrecc.bsky.social #Cancer

Episode 189 Immunotherapy on the Acute Take Part 3: What Every Acute Medic Needs to Know with Dr Dan Beckett – Acute Physician

New Immunobuddies episode Alert! Episode 189 Immunotherapy on the Acute Take Part 3: What Every Acute Medic Needs to Know with Dr Dan Beckett – Acute Physician open.spotify.com/episode/352i... @rickyfrazer1.bsky.social @velindrecc.bsky.social

Five-year overall survival in JCOG1205/1206: irinotecan or etoposide plus cisplatin for resected high-grade neuroendocrine carcinoma of the lung Neuroendocrine tumors of the lung are classified into small cell lung carcinoma (SCLC), typical carcinoid, atypical carcinoid, and large cell neuroendocrine carcinoma (LCNEC) in the current World Heal...

Five-year overall survival in JCOG1205/1206: irinotecan or etoposide plus cisplatin for resected high-grade neuroendocrine carcinoma of the lung. www.lungcancerjournal.info/article/S016...

A systematic review of the implementation of cancer-specific holistic needs assessment (HNA) in adult clinical practice, and applicability to the brain tumour population - Supportive Care in Cancer Purpose This review aimed to identify and review any brain tumour-specific holistic needs assessment (HNA) and the clinical implementation of any HNAs in an adult cancer population. Methods A systemat...

A systematic review of the implementation of cancer-specific holistic needs assessment (HNA) in adult clinical practice, and applicability to the brain tumour population. @velindrecc.bsky.social link.springer.com/article/10.1...

HPV-Associated Oropharyngeal Squamous Cell Carcinoma – Key Updates to the AJCC/UICC TNM9 Staging System - Annals of Surgical Oncology Annals of Surgical Oncology -

HPV-Associated Oropharyngeal Squamous Cell Carcinoma - Key Updates to the AJCC/UICC TNM9 Staging System @velindrecc.bsky.social link.springer.com/article/10.1...

Describing and monitoring quality in value-based palliative and end-of-life care at a population level in Wales: achievements and future direction Improving and monitoring quality of palliative and end-of-life care is well documented within current and historic literature. However, there is a paucity of evidence around national data-informed app...

Describing and monitoring quality in value-based palliative and end-of-life care at a population level in Wales: achievements and future direction. @velindrecc.bsky.social spcare.bmj.com/content/earl...

A Case of Metastatic Melanoma Refractory to Immunotherapy: Is Cytotoxic Chemotherapy Still an Effective Option? Metastatic melanoma is traditionally associated with poor responses to conventional cytotoxic chemotherapy. Although there has been a shift in paradigm in melanoma treatment in the last few decades wi...

A Case of Metastatic Melanoma Refractory to Immunotherapy: Is Cytotoxic Chemotherapy Still an Effective Option? @velindrecc.bsky.social @rickyfrazer1.bsky.social www.cureus.com/articles/440...

The Current Landscape of Artificial Intelligence in Positron Emission Tomography (PET) Imaging Across the #Cancer Continuum. @velindrecc.bsky.social www.mdpi.com/2077-0383/15...

Aspirin and other nonsteroidal anti‐inflammatory drugs (NSAIDs) for preventing colorectal cancer and colorectal adenoma in the general population - Cai, Z - 2026 | Cochrane Library Select your preferred language for Cochrane reviews and other content. Sections without translation will be in English.

Cochrane Systematic Review: Aspirin and other nonsteroidal anti‐inflammatory drugs (NSAIDs) for preventing #ColorectalCancer and colorectal adenoma in the general population. www.cochranelibrary.com/cdsr/doi/10....

Hematological immune-related adverse events associated with checkpoint inhibitors The use of immune checkpoint inhibitors (ICIs) targeting PD-1, PD-L1, or CTLA-4 has increased considerably over the past decade. Initially introduced in the metastatic setting, ICIs are now widely use...

Hematological immune-related adverse events associated with checkpoint inhibitors. www.cancertreatmentreviews.com/article/S030...

Medial retropharyngeal nodal region sparing radiotherapy in nasopharyngeal carcinoma: five year analysis of open label, non-inferiority, multicentre, randomised phase 3 trial Objective To determine the pre-specified long term efficacy (survival and swallowing function) and safety of medial retropharyngeal lymph node (MRLN) region sparing radiotherapy for non-metastatic nas...

Medial retropharyngeal nodal region sparing radiotherapy in nasopharyngeal carcinoma: five year analysis of open label, non-inferiority, multicentre, randomised phase 3 trial. www.bmj.com/content/392/...

Radiographic Progression With and Without Prostate-Specific Antigen Rise in Patients With Advanced #ProstateCancer Treated With Enzalutamide. ascopubs.org/doi/10.1200/...

Conventional vs. Hypofractionated radiotherapy for high-risk prostate cancer (PCS5), randomized, non-inferiority, phase III trial: Post hoc analysis of radiation therapy toxicities and efficacy of IMR... Advances in radiation delivery techniques have markedly enhanced the precision of tumor targeting, allowing enhanced target dose escalation, while minimizing exposure to surrounding healthy tissues [1...

Conventional vs. Hypofractionated radiotherapy for high-risk #ProstateCancer (PCS5), randomized, non-inferiority, phase III trial: Post hoc analysis of radiation therapy toxicities and efficacy of IMRT compared to 3D-CRT. www.thegreenjournal.com/article/S016...

[177Lu]-PSMA-617-PSMA-617 in oligometastatic hormone sensitive prostate cancer (BULLSEYE): an open-label, randomised, phase 2 study 177Lu-PSMA-617 showed promising response rates and delayed disease progression in patients with oligometastatic HSPC in this trial. In addition, most treatment-related adverse events were low grade.

[177Lu]-PSMA-617-PSMA-617 in oligometastatic hormone sensitive #ProstateCancer (BULLSEYE): an open-label, randomised, phase 2 study. www.thelancet.com/journals/lan...

Episode 187 Immunotherapy on the Acute Take: What Every Acute Medic Needs to Know with Dr Dan Beckett – Acute Physician

New Immunobuddies is here, so it must be Friday! Episode 187 Immunotherapy on the Acute Take: What Every Acute Medic Needs to Know with Dr Dan Beckett – Acute Physician. @velindrecc.bsky.social @rickyfrazer1.bsky.social open.spotify.com/episode/1Gsy...

Self-help cognitive behavioural therapy for hot flushes and night sweats during androgen deprivation therapy for prostate cancer: the MANCAN2 randomized controlled trial - British Journal of Cancer British Journal of Cancer - Self-help cognitive behavioural therapy for hot flushes and night sweats during androgen deprivation therapy for prostate cancer: the MANCAN2 randomized controlled trial

Self-help cognitive behavioural therapy for hot flushes and night sweats during androgen deprivation therapy for #ProstateCancer: the MANCAN2 randomized controlled trial. @VelindreCS www.nature.com/articles/s41...

NICE HealthTech Guideline [HTG773]: Artificial intelligence (AI) technologies to help detect or characterise colorectal polyps. www.nice.org.uk/guidance/htg...

Clinical Utility of Deep Learning–based Multiple Arterial Phase MRI in Hepatocellular Carcinoma | Radiology: Imaging Cancer Compared with conventional single arterial phase MRI, deep learning–based ultrafast multiphase arterial MRI improved late arterial phase capture, image quality, and diagnostic performance for hepat...

Clinical Utility of Deep Learning–based Multiple Arterial Phase MRI in Hepatocellular Carcinoma. pubs.rsna.org/doi/10.1148/...

The Rise of Deepfake Medical Imaging: Radiologists’ Diagnostic Accuracy in Detecting ChatGPT-generated Radiographs. pubs.rsna.org/doi/10.1148/...