Model describing how commensal microbes drive the accumulation of Monocytes to the neonatal skin. Depleting these monocytes in the neonatal window leads to an IL-1 dependent aberrant release of IL-17 from cutaneous T cells later in life. This renders mice more susceptible to psoriasiform inflammation in adulthood.
Excited, grateful, and proud to share our latest research published in Immunity. None of this would have been possible without contributions from all our co-authors, across institutions. Shoutout to @scharschmidtlab.bsky.social for her unwavering support over the years! www.cell.com/immunity/ful...