great start to ISSCR annual meeting. great session on immune engineering this morning @isscr.org #isscr2025

Dress to kill. Come to see how I created a novel cancer vaccine by transferring MHC-peptide complexes from tumor cells to universal iPSC-derived Dendritic cells.
#ISSCR2025
AI and Cancer Evolution Session, Friday 8:30am, Convention Hall B, level 1
@ucsfcancer.bsky.social
@ucsfstemcell.bsky.social

so excited to see Huaigeng share this story outside UCSF for the first time.

Congratulations on an amazing paper. A must read.

KMT2C/KMT2D-dependent H3K4me1 mediates changes in DNA replication timing and origin activity during a cell fate transition Gökbuget et al. use machine learning to quantify chromatin state changes that predict DNA replication timing changes during cell differentiation. By following up on top predictors through functional v...

🚨 New Paper Alert! 🚨
Our latest study on KMT2C/KMT2D (mutated in 20% of cancers) reveals a new function for H3K4me1 in regulating DNA replication timing (RT) and origin activity during cell state transitions. Check it out: www.cell.com/cell-reports.... More info ⬇️

Huaigeng Xu at the podium ready to give his presentation.

Huaigeng Xu at the retreat

Huaigeng is presenting his exciting work on developing cancer vaccines today at the UCSF Prostate Program retreat.