Congratulations to Dr. Brittany Reynolds, a former Trainee in the Laboratory of Dr. Alex Carll, who received the Paper of the Year Award from the Cardiovascular Toxicology Specialty Section of the Society of Toxicology at their recent annual meeting.
Posts by Alex Carll, PhD, MSPH
Really proud of Dr. Ramalingam for not only generating but also demystifying this very complicated dataset. Wishing he had been able to visit from Hungary to receive this honor at SOT in person himself.
Next, at the Society of Toxicology conference, on Tuesday afternoon, Dr. Brittany Reynolds, a former PhD student in the Laboratory of Dr. Alex Carll, will present her thesis research showing that beta-blockade prevents e-cigarette-induced arrhythmias during and after pregnancy.#Toxicology#SOT2026
Thirteen of the US NIH’s advisory councils, which must review grant applications before funding is awarded, are on track to have no voting members
go.nature.com/4r6TiIp
US federal agencies were gutted in 2025, losing ~20% of their staff relative to 2024.
Global warming surpassed 1.5 degrees Celsius for the past three years, meaning Earth is currently on track to breach the Paris climate agreement by the end of the decade
While Louisville has plenty of room for improvement, its cycling infrastructure is one of the features I truly appreciate here. I eagerly await my daily bike commutes once I graduate from elementary school taxi driver.
Congratulations to Helen E. Collins on receiving the 2025 International Union of Physiological Sciences International Early-Stage Faculty Prize for her contributions to Physiology. Read more about the award at www.iups.org/academy/awards #cardiosky
Out just in time for New Years' resolutions to quit puffing! Our review of how e-cigs and e-cig constituents cause arrhythmia.
journals.physiology.org/doi/abs/10.115…
@ciehs.bsky.social
@cardiometabosci.bsky.social @uoflenvirome.bsky.socialjournals.physiology.org/doi/abs/10.1...25
🚨🆕🧪🔬on 💓🕒 Delisle et al. 😉show the circadian clock gene BMAL1 drives sex-specific daily patterns in cardiac ion channels ⚡️❤️🔥 in 🐭, shaping when arrhythmias may strike in males vs females 🧠➡️❤️
#Circadian #Physiology #Heart #Arrhythmia #Sex #Science #Cardiosky
www.sciencedirect.com/science/arti...
Congrats to Brittany Reynolds of @cardiometabosci.bsky.social for successfully defending her dissertation today! Way to represent the team with a straightforward talk and meaningful insights how e-cig exposures evoke arrhythmias! Now to get this last cherry on the top submitted and published!
Today’s nanosecond pause in the news cycle 🥱 is a great excuse to hop on over to the AJP-Heart podcast about Brittany Reynolds’ concerning findings that vaping may increase postpartum arrhythmias 😱
E-cigs Promote Arrhythmias During Labor and Postpartum www.podbean.com/ew/pb-9t76s-...
Pregnancy-Related CV Complications Are High & Rising
@emilyswlau.bsky.social @drklindley.bsky.social @abraguo.bsky.social
#CardioObstetrics #ACCRepOB #ACCCardioOB
@accintouch.bsky.social 🔗: www.acc.org/Latest-in-Ca...
@ahajournals.bsky.social 🔗: www.ahajournals.org/doi/10.1161/...
A single dose of psilocybin reduced pain, pain-induced anxiety and depression-like behaviors in mice, according to a study published in Nature Neuroscience. 🧪
Disagreement, sure. 2 schools of thought, no. Most of us realize and routinely acknowledge the uncertainty re: health effects. Advocating for vaping altogether without acknowledging need for regulation to reduce youth appeal and prevent youth uptake seems naive and irresponsible.
This is a false dichotomy. There’s more nuance in the scientific discussion about the merits and/or harms of e-cigs. You somehow missed I am “they” and my “claims” regard my scientific results and their implications, which I believe. The suggestion there are “2 schools of thought” is false.
Thank you for the clearly baited lead into this with an ambiguous loaded question 🤣. I will read these with an open mind as soon as I am able.
What claims, and who are they?
Recent interview about cardiopulmonary risks of vaping:
UofL scientist and physician discuss the health effects of e-cigarettes
Q&A with Alex Carll and Rodrigo Cavallazzi
@uoflenvirome.bsky.social @cardiometabosci.bsky.social @ciehs.bsky.social
www.uoflnews.com/section/scie...
Don’t go vaping my heart, especially when pregnant💨 🫀🤰 Want to know why? Find out more in the latest publication by the Alex Carll, PhD, lab in AJP-Heart, led by PhD student, Brittany Reynolds. journals.physiology.org/doi/abs/10.1...
Proud of Anand Ramalingam for coalescing this data to show repeat e-cigarette exposure transiently evokes arrhythmias via the beta1 adrenoceptor, consistently increases BP, changes the cardiac proteome, and persistently depresses HR and ventricular repolarization. www.ahajournals.org/doi/full/10....
Either the baristas at Heart Rhythm Society are superhuman, or they’re cheating. Either way, kudos #HRS2025
The NCI grant supporting the Columbia comprehensive cancer center was terminated. Tell me how terminating support for cancer research helps the economy.
taggs.hhs.gov/Content/Data...
Tomorrow at #SOT25, Brittany Reynolds, a PhD student in the lab of Dr. Alex Carll, will present her current research on the effects of maternal e-cigarette exposure on cardiac electrophysiology and arrhythmia susceptibility. @sotoxicology.bsky.social @cardiocarll.bsky.social
Tomorrow at #SOT25, Romith Paily, a student in the lab of Dr. Alex Carll, will present his current findings on the effects of heat stress on cardiac electrophysiology and arrhythmia susceptibility. @cardiocarll.bsky.social @sotoxicology.bsky.social
We need to make pregnancy and the postpartum period safe for all women. Currently, maternal mortality rates are at an all time high in the US. In order to make things safer, we need more funding, research, and representation. pubmed.ncbi.nlm.nih.gov/39832282/
🚨🫀🔬 Little et al reveal cardiac fibroblasts as major producers of high molecular weight hyaluronan post-heart attack heart ❤️🩹 Driven by HAS2- this ECM component accumulates but doesn’t impact fibroblast function 👉 journals.physiology.org/doi/abs/10.1...
#CardioSky #Physiology #Science
Interested in moving environmental health research to policy? Join us for the John P. Wyatt Environment and Health Symposium, hosted by the University of Kentucky Center for the Environment.
Register now to attend online or in person: www.research.uky.edu/john-p-wyatt...
"The Healing Power of Trees": Read about the groundbreaking Green Heart Louisville Project in the latest issue of The Nature Conservancy Magazine. Green Heart is the first clinical trial to test a greening intervention the same way new drugs are tested. @nature.org
www.nature.org/en-us/magazi...
This is figure 3, which shows city-level net changes in temperature-related excess death rates for each warming level under scenario SSP3-7.0 and no adaption to heat.
Temperature-related deaths in European cities could increase by up to 50% by the end of the century in the absence of climate change-mitigation policies, totalling up to 2.3 million additional deaths, suggests a paper published in Nature Medicine. https://go.nature.com/4glnYzU 🧪