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Posts by Alex Carll, PhD, MSPH

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Congratulations to Dr. Brittany Reynolds, a former Trainee in the Laboratory of Dr. Alex Carll, who received the Paper of the Year Award from the Cardiovascular Toxicology Specialty Section of the Society of Toxicology at their recent annual meeting.

3 weeks ago 6 3 1 0

Really proud of Dr. Ramalingam for not only generating but also demystifying this very complicated dataset. Wishing he had been able to visit from Hungary to receive this honor at SOT in person himself.

3 weeks ago 0 0 0 0
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Next, at the Society of Toxicology conference, on Tuesday afternoon, Dr. Brittany Reynolds, a former PhD student in the Laboratory of Dr. Alex Carll, will present her thesis research showing that beta-blockade prevents e-cigarette-induced arrhythmias during and after pregnancy.#Toxicology#SOT2026

1 month ago 4 3 1 1
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Exclusive: key NIH review panels due to lose all members by the end of 2026 Thirteen of the agency’s advisory councils, which must review grant applications before funding is awarded, are on track to have no voting members.

Thirteen of the US NIH’s advisory councils, which must review grant applications before funding is awarded, are on track to have no voting members

go.nature.com/4r6TiIp

2 months ago 25 14 0 3
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US federal agencies were gutted in 2025, losing ~20% of their staff relative to 2024.

3 months ago 49 29 2 1
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2025 Wasn’t the Hottest Year on Record. Earth Is Still Barreling to the Climate Brink Global warming surpassed 1.5 degrees Celsius for the past three years, meaning Earth is currently on track to breach the Paris climate agreement by the end of the decade

Global warming surpassed 1.5 degrees Celsius for the past three years, meaning Earth is currently on track to breach the Paris climate agreement by the end of the decade

3 months ago 430 258 17 19

While Louisville has plenty of room for improvement, its cycling infrastructure is one of the features I truly appreciate here. I eagerly await my daily bike commutes once I graduate from elementary school taxi driver.

3 months ago 1 0 0 0
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Congratulations to Helen E. Collins on receiving the 2025 International Union of Physiological Sciences International Early-Stage Faculty Prize for her contributions to Physiology. Read more about the award at www.iups.org/academy/awards #cardiosky

3 months ago 13 4 0 3

Out just in time for New Years' resolutions to quit puffing! Our review of how e-cigs and e-cig constituents cause arrhythmia.
journals.physiology.org/doi/abs/10.115…
@ciehs.bsky.social
@cardiometabosci.bsky.social @uoflenvirome.bsky.socialjournals.physiology.org/doi/abs/10.1...25

3 months ago 2 2 0 0
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BMAL1 mediates sex-specific circadian regulation of cardiac ion channels and temporal arrhythmia vulnerability

🚨🆕🧪🔬on 💓🕒 Delisle et al. 😉show the circadian clock gene BMAL1 drives sex-specific daily patterns in cardiac ion channels ⚡️❤️‍🔥 in 🐭, shaping when arrhythmias may strike in males vs females 🧠➡️❤️
#Circadian #Physiology #Heart #Arrhythmia #Sex #Science #Cardiosky
www.sciencedirect.com/science/arti...

5 months ago 9 5 2 1
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Congrats to Brittany Reynolds of @cardiometabosci.bsky.social for successfully defending her dissertation today! Way to represent the team with a straightforward talk and meaningful insights how e-cig exposures evoke arrhythmias! Now to get this last cherry on the top submitted and published!

5 months ago 1 1 0 0
E-cigs Promote Arrhythmias During Labor and Postpartum In our latest episode, Associate Editor Dr. Jason Carter (Baylor University, Robbins College of Health and Human Sciences) interviews authors Dr. Alex Carll and Brittany Reynolds (University of Louisv...

Today’s nanosecond pause in the news cycle 🥱 is a great excuse to hop on over to the AJP-Heart podcast about Brittany Reynolds’ concerning findings that vaping may increase postpartum arrhythmias 😱

E-cigs Promote Arrhythmias During Labor and Postpartum www.podbean.com/ew/pb-9t76s-...

5 months ago 0 0 0 0
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Pregnancy-Related CV Complications Are High & Rising

@emilyswlau.bsky.social @drklindley.bsky.social @abraguo.bsky.social
#CardioObstetrics #ACCRepOB #ACCCardioOB

@accintouch.bsky.social 🔗: www.acc.org/Latest-in-Ca...

@ahajournals.bsky.social 🔗: www.ahajournals.org/doi/10.1161/...

5 months ago 3 2 0 0
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Single-dose psilocybin rapidly and sustainably relieves allodynia and anxiodepressive-like behaviors in mouse models of chronic pain - Nature Neuroscience Hammo et al. show that a single dose of psilocybin rapidly and sustainably relieves both chronic pain and anxiodepressive-like behaviors in mice by restoring prefrontal activity through partial agonism at 5-HT2A and 5-HT1A receptors.

A single dose of psilocybin reduced pain, pain-induced anxiety and depression-like behaviors in mice, according to a study published in Nature Neuroscience. 🧪

6 months ago 42 13 0 1

Disagreement, sure. 2 schools of thought, no. Most of us realize and routinely acknowledge the uncertainty re: health effects. Advocating for vaping altogether without acknowledging need for regulation to reduce youth appeal and prevent youth uptake seems naive and irresponsible.

6 months ago 1 0 2 0

This is a false dichotomy. There’s more nuance in the scientific discussion about the merits and/or harms of e-cigs. You somehow missed I am “they” and my “claims” regard my scientific results and their implications, which I believe. The suggestion there are “2 schools of thought” is false.

6 months ago 1 0 2 0

Thank you for the clearly baited lead into this with an ambiguous loaded question 🤣. I will read these with an open mind as soon as I am able.

6 months ago 1 0 1 0

What claims, and who are they?

6 months ago 0 0 1 0
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UofL scientist and physician discuss the health effects of e-cigarettes | UofL News Many people believe that electronic cigarettes are less harmful than traditional cigarettes, but research at the University of Louisville School of Medicine has shown that electronic cigarettes have a...

Recent interview about cardiopulmonary risks of vaping:

UofL scientist and physician discuss the health effects of e-cigarettes
Q&A with Alex Carll and Rodrigo Cavallazzi
@uoflenvirome.bsky.social @cardiometabosci.bsky.social @ciehs.bsky.social
www.uoflnews.com/section/scie...

6 months ago 4 3 1 0
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Don’t go vaping my heart, especially when pregnant💨 🫀🤰 Want to know why? Find out more in the latest publication by the Alex Carll, PhD, lab in AJP-Heart, led by PhD student, Brittany Reynolds. journals.physiology.org/doi/abs/10.1...

7 months ago 8 5 1 0
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Acute and Persistent Cardiovascular Effects of Menthol E‐Cigarettes in Mice | Journal of the American Heart Association

Proud of Anand Ramalingam for coalescing this data to show repeat e-cigarette exposure transiently evokes arrhythmias via the beta1 adrenoceptor, consistently increases BP, changes the cardiac proteome, and persistently depresses HR and ventricular repolarization. www.ahajournals.org/doi/full/10....

11 months ago 1 3 0 0
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Either the baristas at Heart Rhythm Society are superhuman, or they’re cheating. Either way, kudos #HRS2025

11 months ago 0 0 0 0

The NCI grant supporting the Columbia comprehensive cancer center was terminated. Tell me how terminating support for cancer research helps the economy.

taggs.hhs.gov/Content/Data...

1 year ago 395 240 19 39
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Tomorrow at #SOT25, Brittany Reynolds, a PhD student in the lab of Dr. Alex Carll, will present her current research on the effects of maternal e-cigarette exposure on cardiac electrophysiology and arrhythmia susceptibility. @sotoxicology.bsky.social @cardiocarll.bsky.social

1 year ago 5 2 0 0
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Tomorrow at #SOT25, Romith Paily, a student in the lab of Dr. Alex Carll, will present his current findings on the effects of heat stress on cardiac electrophysiology and arrhythmia susceptibility. @cardiocarll.bsky.social @sotoxicology.bsky.social

1 year ago 5 2 0 0
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Maternal cardiovascular research and education should be prioritized in the United States - PubMed Maternal cardiovascular research and education should be prioritized in the United States

We need to make pregnancy and the postpartum period safe for all women. Currently, maternal mortality rates are at an all time high in the US. In order to make things safer, we need more funding, research, and representation. pubmed.ncbi.nlm.nih.gov/39832282/

1 year ago 15 7 1 0
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🚨🫀🔬 Little et al reveal cardiac fibroblasts as major producers of high molecular weight hyaluronan post-heart attack heart ❤️‍🩹 Driven by HAS2- this ECM component accumulates but doesn’t impact fibroblast function 👉 journals.physiology.org/doi/abs/10.1...
#CardioSky #Physiology #Science

1 year ago 4 3 1 0
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Interested in moving environmental health research to policy? Join us for the John P. Wyatt Environment and Health Symposium, hosted by the University of Kentucky Center for the Environment.

Register now to attend online or in person: www.research.uky.edu/john-p-wyatt...

1 year ago 1 1 0 0
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The Healing Power of Trees: A tree planting project improves the peoples' health Adding 8,000 trees to a neighborhood in Louisville, Kentucky, improves health conditions that are linked to heart disease, stroke and some types of cancer.

"The Healing Power of Trees": Read about the groundbreaking Green Heart Louisville Project in the latest issue of The Nature Conservancy Magazine. Green Heart is the first clinical trial to test a greening intervention the same way new drugs are tested. @nature.org

www.nature.org/en-us/magazi...

1 year ago 2 2 0 0
This is figure 3, which shows city-level net changes in temperature-related excess death rates for each warming level under scenario SSP3-7.0 and no adaption to heat.

This is figure 3, which shows city-level net changes in temperature-related excess death rates for each warming level under scenario SSP3-7.0 and no adaption to heat.

Temperature-related deaths in European cities could increase by up to 50% by the end of the century in the absence of climate change-mitigation policies, totalling up to 2.3 million additional deaths, suggests a paper published in Nature Medicine. https://go.nature.com/4glnYzU 🧪

1 year ago 73 30 2 2