a close up of a man 's face with his eyes closed and a piece of paper in front of him . ALT: a close up of a man 's face with his eyes closed and a piece of paper in front of him .

Genius

“You are an abolitionist, ain’t you?” “As to that, I cannot so readily answer. If by abolitionist you mean a zealot, I am none; but if you mean a man, who, being a man, feels for all men, slaves included, and by any lawful act, opposed to nobody’s interest, and therefore, rousing nobody’s enmity, would willingly abolish suffering (supposing it, in its degree, to exist) from among mankind, irrespective of color, then am I what you say.” “Picked and prudent sentiments. You are the moderate man, the invaluable understrapper of the wicked man. You, the moderate man, may be used for wrong, but are useless for right.”

Herman Melville on moderates, all the way back in 1857:

This is your brain.
This is your brain on exercise.
This dataset collected over 5 years ago captivated our neuroscience lab.

Loving this whole data and computation packed final panel of #acnp2026 on sex differences and similarities in the organization of the brain helmed by @elvisha.bsky.social, @bogglerapture.bsky.social, Jason Lerch, and @tollkuhn.bsky.social

Preprint updated -->

Key new results: we found a brain-behavior correlation between performance on an RL task (under short feedback delays) and short-delay RPE signals in the 'cognitive' cerebellum!

www.biorxiv.org/content/10.1...

This summer, the #BetleyLab at
@upenn.edu celebrated 10 years of exploring the fascinating dialogue between the body and the brain 🧠<>💪
From hunger to exercise, it's been an incredible decade of discovery. Follow along as we share some highlights over the next couple of weeks!

Three arm study: real / sham / Lego

Options include:
A) Doesn’t Fit
Or
B) Duck repeatedly forever

Brain Connectivity Linked With Cognition in People With Early Psychosis An NIMH-funded study identified consistent links between brain connectivity and cognitive function in people with early stage psychosis and people at high risk who later developed psychosis.

Thanks for the coverage NIMH !
(Anyone know if NIMH is on Bluesky?)

www.nimh.nih.gov/news/science...