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This was my first family trip abroad and I spent a lot of time jumping over bollards in London, four decades ago. Highly recommend

Countdown to #GAMRIC2025: The inaugural Global AMR Innovators Conference kicks off tomorrow in London!

Join CARB-X and global leaders as we dive into discussions about #AMR policy and antimicrobial research and development. #GlobalHealth #CARBX #IDSky 🧪

New insights into the role of IFN-α/β and TLR7/8/9 in cancer immunotherapy and systemic autoimmunity The role of type I interferon (IFN) in mediating tumor immunosurveillance, in situ vaccination, and response to other cancer immunotherapies is well established. The biologic and species-specific diff...

My new review article covers key points I have not seen in any other review of cancer immunotherapy: i) the difference between IFN-a and IFN-b; ii) the unique role of P1 pDC among all DC subsets; iii) the unique role of TLR7/8/9 among TLRs
nam10.safelinks.protection.outlook.com?url=http%3A%...

Congrats, Adam!

Human iPSC derived alveolar macrophages reveal macrophage subtype specific functions of itaconate in M. tuberculosis host defense M. tuberculosis must survive within multiple macrophage populations during infection, including alveolar macrophages (AM) and recruited inflammatory macrophages. In mice, itaconate, produced in macrop...

Happy to share the most recent preprint from the lab, the thesis work of Dr. Adam Krebs and a collaboration with many, including the Geissmann lab @mskcancercenter.bsky.social
Here is a short paper thread. #tuberculosis #macrophages 🦠
www.biorxiv.org/content/10.1...

We are on the lookout for postdocs for two different projects at the intersection of ecology, evolution, and the human microbiome.

See thread for more information and reach out!

There is only one way to end the war: put pressure on the Russians. The Trump people did the opposite: put pressure on Ukraine, and relieved pressure on Russia. They have made the war worse while talking of "peace."

Merci, EmmanuelMacron 💙💛

Every European will be safer if every part of Ukraine is sovereign and pro-European.

russian occupation of an independent country creates a precedent that endangers the entire continent.

Detecting microbial engraftment after FMT using placebo sequencing and culture enriched metagenomics to sort signals from noise - Nature Communications Here, the authors profile bacterial engraftment in UC patients receiving FMT from a single donor and placebo samples to estimate noise, showing a significant level of false-positive engraftment, which...

A lot of what looks like microbial engraftment after FMT might actually be noise. Using placebo sequencing and culture-enriched metagenomics, we sort signal from noise. Our latest from the Surette lab: www.nature.com/articles/s41... @surettem.bsky.social @mcmasteruniversity.bsky.social

Preserving and Modernizing the FDA — No Patient Left Behind

www.nopatientleftbehind.org/preserving-t...

Link broken

Our expectations for you were low but holy f*ck

Sign of the day…Chicago

looking forward to #ESCMIDGlobal next week in Vienna. I'd love to connect and discuss developing microbiome drugs to prevent infection. Come to the Innovation Theater 12 April at 11:30!

sorry to hear 😞

Everything

I have a trade deficit with Trader Joe's, who are so unfair because they never buy anything back from me, so I will have to impose some tariffs.

Why we keep going Today thousands of health workers at the CDC and FDA lost their jobs—effective immediately.

I can feel the pain in this summary at the end of the day. A lot of people trying to collect themselves. More pain to come. Will need to strengthen our common ties to advance the public health and individual medical outcomes.

yourlocalepidemiologist.substack.com/p/why-we-kee...

The Trump Administration Accidentally Texted Me Its War Plans U.S. national-security leaders included me in a group chat about upcoming military strikes in Yemen. I didn’t think it could be real. Then the bombs started falling.

From an operational security perspective, this is the highest level of fuckup imaginable. These people cannot keep America safe.

Gustavo Dudamel - Beethoven: Symphony No. 7 - Mvmt 2 (Orquesta Sinfónica Simón Bolívar) YouTube video by Gustavo Dudamel

How Beethoven could come up with this absolute marvel when he was dealing with hearing loss is beyond my comprehension. It's like he found a secret shortcut to reach the soul.

youtu.be/ESilvOS2O9k

Profundament vergonyós. No sé què dir. Donant suport a un terrorista i humiliant els aliats amb actituds de quinqui de barri. Respira fondo. Dema serà una altre dia.

Our gut microbiome and its metabolites have key interactions with our immune response to cancer and success from cancer immunotherapy. Nice perspective @jclinical-invest.bsky.social www.jci.org/articles/vie...

thanks

Thanks Patrick. Is there any publication out from this MIT effort?

Metagenomic global survey and in-depth genomic analyses of Ruminococcus gnavus reveal differences across host lifestyle and health status - Nature Communications Here, the authors present a global meta-analysis of the human gut bacterium Ruminococcus gnavus, established an isolate collection with complete genomes and identified genetic features correlating wit...

www.nature.com/articles/s41...

excellent setup!

So you trap Doug in a cold frozen mountainside and then you ask him softly if he wants to join your Board? Sounds like a Godfather-type offer you can't refuse 😂

Discovered by the Germans in 1904...

Vedanta Biosciences Publishes Additional Phase 2 VE303 Results in Nature Medicine Vedanta Biosciences, a late clinical-stage company developing defined bacterial consortia as oral therapies for gastrointestinal diseases, today annou

www.businesswire.com/news/home/20...

The Second Trump White House Could Drastically Reshape Infectious Disease Research. Here’s What’s at Stake. Donald Trump’s pick to lead the federal health agency has vowed to replace hundreds of staffers and shift research away from infectious diseases and vaccines. Such an overhaul could imperil the develo...

I hope the new administration can appreciate that basic research in infectious diseases is also a matter of national security, which we all care about no matter who we vote for

www.propublica.org/article/nih-...