Geographic divergence of methicillin-resistant Staphylococcus aureus ST5-SCCmecI in the aftermath of a major earthquake and tsunami: impact of a plasmid harboring heavy metal resistance genes | mBio Methicillin-resistant Staphylococcus aureus (MRSA) is a major cause of life-threatening infections worldwide and a growing public health concern. The rise of antibiotic-resistant bacteria, such as MRSA, is often linked to genetic adaptations that enhance ...

Proud to be part of this group! journals.asm.org/doi/10.1128/...

What Do We Gain When Tolerating Loss? The Information Bottleneck Wrings Out Recombination Abstract. Most microbes have the capacity to acquire genetic material from their environment. Recombination of foreign DNA yields genomes that are, at leas

Here is our latest on finding recombination in microbial genomes. No alignment, no phylogeny. Just information theory. Congrats Apurva and the whole team! This one was a pongvtime coming. academic.oup.com/mbe/article/...

What Do We Gain When Tolerating Loss? The Information Bottleneck Wrings Out Recombination Abstract. Most microbes have the capacity to acquire genetic material from their environment. Recombination of foreign DNA yields genomes that are, at leas

academic.oup.com/mbe/article/...

This study was made possible through an amazing collaboration across the CHOP NICU, CHOP Infectious Disease Diagnostics Lab (IDDL), CHOP Infection Prevention and Control, the Microbial Archive and Cryocollection at CHOP (MicrobialARC), and @centermicrobialmed.bsky.social.

In this study we tracked carriage, transmission, and invasive infection with S. aureus across 33 months in the NICU. Using longitudinal WGS, we identify risk factors for transmission of invasive clones, and show strains that are transmitted more rapidly are more likely to cause invasive disease

Transmission of Staphylococcus aureus in the neonatal intensive care unit predicts invasive infection Background Staphylococcus aureus is a leading cause of healthcare-associated infection and is one of the most common pathogens causing serious invasive infection in the neonatal intensive care unit (N...

Excited to share our work with @pjplanet.bsky.social and @ahmedmicrobes.bsky.social tracking Staph aureus transmission across the NICU using genomics!!

This study was co-led by the amazing @qianxuan.bsky.social and Lakshmi Srinivasan, and made possible by the @centermicrobialmed.bsky.social

Transmission of Staphylococcus aureus in the neonatal intensive care unit predicts invasive infection Background : Staphylococcus aureus is a leading cause of healthcare-associated infection and is one of the most common pathogens causing serious invasive infection in the neonatal intensive care unit ...

Our preprint on genomic epidemiology in the NICU! Strains that transmit faster also cause more invasive disease! nam10.safelinks.protection.outlook.com?url=https%3A...