5th Anniversary Thematic Collection: Manipulating DNA Repair and the DNA Damage Response to Improve Cancer Therapy url:academic.oup.com/narcancer/pages/manipula... @emgsus.bsky.social @weldeiry.bsky.social
Fantastic review from my former colleague Ming Tan: Exploiting metabolic vulnerabilities to improve cancer therapeutics: Trends in Endocrinology & Metabolism www.cell.com/trends/endoc...
Great to see our latest study out in NAR Cancer: Replication-associated base excision repair/single-strand break repair regulates PARG inhibitor response via the PRMT1/PRMT5/ATR axis url: academic.oup.com/narcancer/ar... @weldeiry.bsky.social @emgsus.bsky.social
Great to see our latest study out in NAR Cancer: Replication-associated base excision repair/single-strand break repair regulates PARG inhibitor response via the PRMT1/PRMT5/ATR axis url: academic.oup.com/narcancer/ar... @weldeiry.bsky.social @emgsus.bsky.social
Fantastic review from my former colleague Ming Tan: Exploiting metabolic vulnerabilities to improve cancer therapeutics: Trends in Endocrinology & Metabolism www.cell.com/trends/endoc...
Great opportunity at NAR @emgsus.bsky.social @ianywonglab.bsky.social @weldeiry.bsky.social
Check out this article from USA TODAY:
Olympics organizers willing to treat Trump like a toddler to protect 2028 LA Games | Opinion
www.usatoday.com/story/sports...
RNF114 is an E3 ligase that can recognize ADP-ribose (ADPr) and ubiquitin with separate domains. A proteomics approach is developed using these domains to map ADP-ribosyl-ubiquitylation sites
www.nature.com/articles/s41...
A few years back we discovered a dual hybrid protein modification composed of ADP-ribose dinucleotide and ubiquitin (ADPr-Ub). Now we reveal that ADPr-Ub can be further ubiquitinated by the E3 ubiquitin ligase RNF114!
www.nature.com/articles/s41...
www.science.org/doi/10.1126/...
Blue and green background with white text that reads "GP2 Data Update, Release #10" and a small icon below the text.
🔔 GP2’s 10th data release is live on the cohort dashboard!
It includes a new family file and data discovery report with pairwise kinship estimates, capturing both inferred and reported relationships.
🧪 Learn more: gp2.org/the-components-of-gp2s-10th-data-release/
Congratulations to Mark Hedglin, PhD: the 2025 Samuel H. Wilson Award for Studies on DNA Repair Winner @emgsus.bsky.social emgs-us.org/news/news.as...
Thrilled to share how proteomic analysis led to the discovery of "TRIP12’s role in the governance of DNA polymerase β involvement in DNA damage response and repair" url: academic.oup.com/nar/article/... @ianywonglab.bsky.social @weldeiry.bsky.social @emgsus.bsky.social
👇we must resist
Judge rules some NIH grant cuts illegal, saying he's never seen such discrimination in 40 years
apnews.com/article/nih-...
NIH scientists publish declaration criticizing Trump's deep cuts in public health research
apnews.com/article/nih-...
Check out our latest: DNA polymerase beta expression in head and neck cancer modulates the poly(ADP-ribose)-mediated replication checkpoint: www.sciencedirect.com/science/arti... @weldeiry.bsky.social @emgsus.bsky.social
All of us are in grave danger this year before of this inept fascist takeover
Remember folks, the budget cuts for NSF and NIH *can still be stopped*. That is a luxury not granted to our agency science colleagues who have or could still lose their jobs from the top down. So - Fight! Speak up! Pay attention!
NSF Physics was cut by 85%, basically wiping out most of its capacity for supporting research.
NSF Astronomy was cut by 53%
Undergrad education was cut by 71% and research on learning by 79%
Graduate education was cut by 100% to ZERO.
#GiftLink ⚛️🔭
www.nytimes.com/interactive/...
Interested in proteins that bind to poly(ADP-ribose)? Check out our recent study here at the Legorreta Cancer Center at Brown University on WWE domains and binding to poly(ADP-ribose) in cells: www.sciencedirect.com/science/arti... @brownuresearch.bsky.social @weldeiry.bsky.social
Innovation takes time
US scientists who received renewals from the NIH over the past four decades produced more novel research than those who didn’t
https://go.nature.com/44oKEwV
A US judge to govt lawyers defending the NIH's grant terminations:
"I understand the administration is against DEI. Respectfully, I just don't know what you mean. This isn't a teasing question. There has to be some working definition.
This is research to advance healthcare for all our citizens."
Due to great enthusiasm, we are extending the early bird registration deadline, at a reduced rate, until 25 May. After this date, the rate will increase by 1500NOK (approx. 135USD). We look forward to seeing you in Trondheim! www.endodnadamage.com
