โHence, after spinal cord injury, a pro-regenerative neutrophil subpopulation promotes spinal cord regeneration in larval zebrafish by controlling expression of il1b in macrophages/microglia. For this neutrophil action, il4 expression is necessary & sufficient.โ
New from @beckergroup.bsky.social ๐
Posts by Kim Heilemann
Are you interested on how regenerating tissues transit between stages? Am sharing here our work showing that during #Xenopus tail regeneration, tissue stiffening activates a Piezo1-Yap1 mechanosensitive cascade to allow wounded epithelia to transit into regenerative states!
Zebrafish larvae are really good for time lapses. Just take some popcorns enjoy them like if they were movies. Here you can see with your own eyes how immune cells divide. This one I call it "Divide and flee" #spinalcordregeneration #zebrafish #timelapse #microglia
For a while now, weโve been living in turbulent times, be aware how this might affect your postgrads and others around youโฆ www.nature.com/articles/d41...
๐ Over 2,200 visitors, 250+ volunteers, and one unforgettable Science Night at the CMCB, @tudresden.bsky.social!
Huge thanks to everyone who joined us โ and to our amazing volunteers!
#LNDWDD #Dresden #CMCBnews
Gearing up for the long night of science ๐ฌ๐ฅผ๐งช๐งฌ
Come and visit us!
An artistic and colorful illustration promoting "Long Night of Science Dresden." The image features two striped fish (likely zebrafish) swimming amidst swirls of blue, orange, and purple smoky elements. Various scientific motifs are present, including test tubes filled with red liquid, floating bubbles, a microscope, and what appears to be a stylized eye. The overall impression is dynamic and visually engaging, representing scientific exploration and discovery.
Ready for a deep dive? ๐๐ฌ Explore "Zebrafish in action: Tiny fish, big science" at the Long Night of Science Dresden this Friday, June 20th, from 5 PM to midnight! We're on the 3rd floor at CRTD. See how these small fish lead to big breakthroughs in science. #LNDWDD #zebrafish @cmcb-tud.bsky.social
#ICYMI Bioinformatics Bootcamp โ Zebrafish Special Edition
@kevinthiessen.bsky.socialโฌ compiled a very useful collection of resources for those working with #zebrafish and beyond. Have fun exploring!
The next 13th of May Iโll be taking about microglia in spinal cord regeneration. If youโre interested ๐๐ป๐๐ป
Gentle reminder: we do this in our own time. We help your posts reach out as many people as possible because we care about the community.
A Star Protocols graphical abstract of the steps for the preparation, clearing and visualization of adult zebrafish spinal cords, together with alternative uses for these samples (e.g. cryosectioning and immunohistochemistry of reverted sectioned samples).
The first work of my PhD is OUT ๐
star-protocols.cell.com/protocols/38...
In this work, we share with the community our protocol for preparation, clearing and visualization of adult ๐ฆ๐ spinal cords structures that has been tested, refined and used quite frequently in our lab.
This is my first post here, and I'm happy to share some news. We've just launched megabouts.ai! ๐๐
1/n
Bringing vibrant #fluorescentfriday vibes in #zebrafish spinal cord #regeneration โfinally completing the migration to Bluesky. Excited for all new and old!
I created a simple flow chart to help my lab trainees choose the most appropriate stats test in Prism (*for single-factor comparisons only). Feel free to share with your group if you think it could be helpful first start.
Very happy to share my first preprint as a postdoc in the Becker Lab ๐ฅณ If you are interested in cell-cell interactions during spinal cord regeneration feel free to have a look ๐ #spinalcord #regeneration #zebrafish
www.biorxiv.org/content/10.1...
I havenโt tried it personally, but I think itโs worth trying especially for some problematic genes. Its ability to reduce secondary structures might help, and at low concentrations, it shouldnโt negatively impact the reaction.