Differential phagocytosis induces diverse macrophage activation states in malignant gliomas Background Diffuse midline glioma (DMG) and glioblastoma (GBM) are aggressive brain tumors with limited treatment options. Macrophage phagocytosis is a complex, tightly regulated process governed by c...

Excited to announce our latest manuscript!
burning question: do macrophages feel the same after “eating” a tumor cell as we do after a bean burrito vs. a kale salad? macrophages are reprogrammed by what they ingest.

jitc.bmj.com/content/13/9...

Finally a Mitra/Hankinson lab outing. Fully rebuilt after COVID. Celebrating birthdays and just each other

Immune evasion through mitochondrial transfer in the tumour microenvironment - Nature Mitochondria with mutations in their DNA from cancer cells can be transferred to T cells in the tumour microenvironment, which leads to T cell dysfunction and impaired antitumour immunity.

An absolutely phenomenal paper: Cancer cells can poison attacking immune cells by filling them with defective mitochondria ― dampening the body’s defensive forces and helping the tumour to evade eradication
www.nature.com/articles/s41...

This is awesome. Thanks for starting it

Awesome meeting up with former lab member Sharareh Gholamin and Johana Theruvath at #SNO2024

Phenomenal talk by Doug Hanahan on the intersection of cancer neuroscience and Immunology #SNO2024

Hope I'm the first to post this all time classic on this platform

Report: Every dollar of NIH research funding doubles in economic returns Research funded by the National Institutes of Health (NIH) generated $2.46 in economic activity for every $1 of funding in 2023, a total of $92.9 billion, according to an

Terrific piece summarizing a recent report: Every dollar of NIH research funding doubles in economic returns

www.fiercebiotech.com/research/rep...

Yes!!! He is coming away from the dark ages… we need to bring our institutes here as well