So the survivors are still cancer-free six years later. I was hoping for the phase 2 results, but this is very good.

Systematic discovery of pro- and anti-HIV host factors in primary human CD4+ T cells Genome-wide CRISPR activation and knockout screens in primary human CD4+ T cells systematically identify host proviral and antiviral factors modulating HIV infection, including the strongly antiviral ...

important work from my @gladstoneinst.bsky.social and @ucsanfrancisco.bsky.social colleagues (also @harmitmalik.bsky.social!) on pro- and anti-HIV host factors. Just when you thought we couldn't do more! www.cell.com/cell/fulltex...

I would brine lots of chickens with this if that’s what it does

AAAAAAAAAAAAHHHHHHHHH

Been following this closely. Tomorrow’s results should be good. Large cohort.

Survive till when? Not much more than 1-3 years if that. Mets always show up even post-whipple

In Toronto #2 and terraces

Where U.S. science has been hit hardest after Trump’s first year The Trump administration has slashed the number of grants from the National Institutes of Health, with far fewer focused on women, cancer and mental health.

Those of us doing research related to women’s health have been hit particularly hard by the govt’s sabotage of the NIH. I spoke to WaPo for this piece, as painful as it was to discuss the reality my lab is facing. www.washingtonpost.com/science/2026...

Sure is. Keep forgetting that Jools wasn’t just a tv host

Junior prom

Let’s see Monday what the trial shows. I bet it’s amazing.

always!

Normally my pop-up ads are for shirts and shoes….

civilized gentle leaders.

Hmm. I’m neither of those (well maybe the hot?) but my ND is irrespective of all that.

Ah he’s not. Bummer

Normally not a fan of telecasters, but Johnny Greenwood has me a convert. Also Bill Frisell but that’s a different league

Goals

San Francisco. There was a fourth one behind me

Next next president for sure

I unlikely could be reek it seems at this point

Wish I was there

well done! Good piece on an important study

a two panel meme panel 1 - geordi signalling 'no' with the text data centres and images of data centres Panel 2 - geordi signalling 'yes' with the text "data centaurs" and a crudely edited image of the character data from star trek pasted on top of a centaur

do you ever wake up at 3am and think "shit that's a good idea, I better write that down so I can share it later on"

oh yeah. I had an illuminating conversation with a guitar shop that explained why my recent delivery had a defective pickup

go home biology, you’re drunk.
reverse transcriptase is now taking sequence instructions from a protein

Oh yeah! This and Massive Attack + Tom Waits is what we need right now

Do you know if postdocs with a K99 can get this on top of it?

Comic. [Person and person with white hat facing two boxes stacked with $80 price tag and sale tag on each box.] PERSON 1: They want $80 for this? I could make one myself for $10 in parts, an hour of work, a trip to the hardware store, another $30 in parts, another few hours of work, two more trips to the store for $20 more in parts, another hour of work to redo the first hour of work because I messed up, and $80 to buy this when the one I made breaks.

Make It Myself

xkcd.com/3233/

my dream car. If I didn't have kids in private school and college I'd snap it up