Clonal hematopoiesis driven by Dnmt3a mutations promotes metabolic disease development in mice
Olga A. Guryanova & team report an aging-related condition caused by mutations in the blood system promotes obesity and drives the risk of #diabetes & #MASLD with a high-fat diet: doi.org/10.1172/JCI1...
We are seeking a highly motivated PhD candidate to investigate how altered communication between leukaemic stem cells and the bone marrow niche drives leukemogenesis.
The function of blood stem cells is critically governed by their dynamic, bidirectional interactions within the bone marrow niche. When these cells turn leukaemic, the crosstalk with their environment changes dramatically, fuelling disease progression.
www.findaphd.com/phds/project...
Join us in York 🇬🇧 for the 1st Advances in Experimental & Therapeutic Haematopoietic Stem Cell Expansion (HExaT) Meeting!
📅Workshops + 1-day scientific programme
🎙️ Keynotes: Yamazaki, Laurenti, Nakauchi, Essers, Schroeder
🧬 Registration: sites.google.com/york.ac.uk/h...
#HExaT2025
New opportunity - this is a non clinical PhD 4 year program - have a look and DM me if wish to discuss this particular student ship in modelling high risk Leukemia.
If that doesn’t take your fancy - there are plenty of exciting projects here!
@uom-dcs.bsky.social @mcrcnews.bsky.social @uomsociology.bsky.social
Many cancers begin as precancerous conditions. But what happens when these early cells coexist with a full-blown tumour?
Join us for an MRC funded PhD studentship exploring how primary cancers influence the evolution of precancerous cells.
www.findaphd.com/phds/project...
We have a new PhD studentship in the lab on the immunogenic roles of transposable elements in paediatric acute myeloid leukaemia! Come and work with us! www.colcc.ac.uk/2026-cyp-phd...
Very interesting finding! It would be super cool if this can be validated in on-going or future clinical trials testing Menin inhibitors.
Many congratulations!
Today is the last day for discounted registration! We have space for 3-4 more posters...shoot me an email if you would like to present a poster! maxsonj@ohsu.edu
Huge congratulations to Yu-Hung Wang, who has been honoured with the Best Outstanding Research Contribution Award from the FBMH Doctoral Academy at the University of Manchester! We are incredibly proud of Yu-Hung's dedication and hard work!
A graphic for the Marie Skłodowska-Curie Actions (MSCA), showing a historical portrait of Marie Skłodowska-Curie overlaid with an image of four young researchers walking down a hallway. The European Commission logo is in the top left. Text reads: "Marie Skłodowska-Curie Actions – €404.3 million to support postdoctoral researchers”
Choose Science. Choose Europe.
A new Marie Skłodowska-Curie Actions Postdoctoral Fellowships 2025 call is now open.
With a budget of €404.3 million, it will support around 1,650 researchers from Europe and beyond.
Apply by 10 September → europa.eu/!fBTMgF
Hey #HemeSky and #EpiSci folks! We are hiring!
For our Translational Cancer Epigenomics team @dkfz.bsky.social and @nct-heidelberg.bsky.social we are looking for a talented postdoc interested in research on heme malignancies and #epigenetics.
Interested?
👉See jobs.dkfz.de/en/jobs/1676... or DM me!
Just over 24 hours to get your abstract submitted
The induction of SCL and LMO2 leads to conflicting haematopoietic and neuronal fates; therefore, inhibiting the pathway associated with neuronal fate enhances reprogramming to haematopoietic progenitor cells.
This study describes the development of a model allowing the reprogramming of fibroblasts to haematopoietic progenitor cells via the induction of two transcription factors, SCL and LMO2.
Excited to share our work published in Stem Cell Reports!
www.cell.com/stem-cell-re...
This work was primarily led by Samiyah Shafiq, PhD, with co-supervision from Georges Lacaud @cruk-mi.bsky.social and Jon @The Cell Fate Engineering and Therapeutics Laboratory
💥Exciting new #postdoc opportunities in my lab at @cruk-mi.bsky.social i.bsky.social to study #NutrientHostMicrobiome interactions in #CancerImmunity in mice and humans. #CancerImmunology#MucosalImmunology#Microbiome
⏰Deadline: 4 April 2025
Apply👇
www.cruk.manchester.ac.uk/career/mi-24...
⏩RT
Resistin also induces myeloid-derived immune suppressive features in monocytes, leading to an expansion of regulatory T cells. @uom-dcs.bsky.social @mcrcnews.bsky.social
www.biorxiv.org/content/10.1...
In this preprint, we showed that granulocytes from CMML patients are immature and produce high levels of an adipokine called Resistin. Resistin binds to monocytes and prevents their maturation, potentially contributing to the monocytosis phenotype in CMML.
CRUK Black Leaders in Cancer Non-Clinical PhD Opportunity in my lab using unique pt models
‘Phosphatases in melanoma metastasis +therapy resistance’
📅 Deadline: 4 April
🔗www.crukcentre.manchester.ac.uk/opportunities/the-role-o...
Gloved hands holding a pipette and tube in a laboratory setting
Find out more about our #PhDStudent program, currently recruiting for an exciting position in our Stem Cell Biology Research Group:
"Development of Novel Cellular Platforms for Immunotherapies"
Full details and link to apply 👇
www.cruk.manchester.ac.uk/phd-student-...
#CancerResearch #PhD
PhD applicants of Black or mixed Black heritage are encouraged to apply to our lab via the Crick's inaugural recruitment for Future Leaders in Biomedical Sciences Scholarships.
www.crick.ac.uk/careers-and-...
Interested in investigating the principles that regulate the establishment of tumour environments that promote or inhibit the anti-tumour function of the immune system? Our group is currently recruiting a postdoctoral fellow.
Learn more about our research 👇
www.cruk.manchester.ac.uk/research-gro...
Very interesting
We are looking to recruit a highly motivated postdoc with cell or molecular biology expertise. Excellent #epigenetics, #chromatin training & networking opportunities @qmulepigenetics.bsky.social
DM me for inquiries
pl apply/share tinyurl.com/m6jnksk5
OK folks, I have now created a google form that allows people to sign to show their support for my open letter to the President of the Royal Society. Please sign and share widely: forms.gle/miDciq35oxyw...