Why does the brain clear waste during sleep but not wakefulness? New preprint: brain tissue acts as a low-pass filter (cutoff ~0.05 Hz). Cardiac pulsations are 99% attenuated. Only slow-wave sleep generates forcing slow enough to drive bulk flow. doi.org/10.64898/202...

I very much enjoyed reading Melinda Bonnie Fagan‘s recent book _ Explanatory Particularism in Scientific Practice_ and writing a review of it. Check it out!

rdcu.be/fdagG

#philsci #philbio

Faster adult implicit probabilistic statistical learning following childhood adversity Abstract. According to deficit models, early life adversity disrupts normal development, leading to long-term emotional, behavioural and cognitive difficul

If childhood adversity is harmful, are its cognitive consequences always and only negative?

Maybe we need to question deficit models.

Greater childhood adversity was linked to faster implicit learning in our new study.

royalsocietypublishing.org/rsos/article...

#neuroskyence

Out now in @natcomms.nature.com, our latest from @bodybrainbehaviour.bsky.social: Visual perception, oscillatory excitability markers, and network connectivity are modulated by the breathing rhythm - depending on how much you know about the stimulus.

#brainbody #neuroskyence

Dennett's Real Patterns in Science and Nature How the concept of a pattern, as understood in information science and applied in contemporary AI, can address deep questions in science and philosophy.The

Daniel Dennett’s Real Patterns in Science and Nature— new collected volume is now out. All chapters open access, including my paper with Acyuth Parola on what emergence can possibly mean.

direct.mit.edu/books/oa-edi...

Please join us for this fantastic double-book symposium on @hohwy.bsky.social's and @kathrynnave.eurosky.social's books.

Register here for the link: docs.google.com/forms/d/e/1F...

REM-sleep twitching in adults and the maintenance of specialized sensorimotor systems Blumberg et al. present video evidence of twitching during adult sleep in a diverse sample of animals. Adult twitching appears to selectively involve appendages used for active sensing, mirroring thei...

New paper (with lots of cute animal videos!)

Ever watch your dog "run" while asleep and wonder what’s going on in their brain? In Current Bio we suggest that those twitches aren't just leaky dreams—they’re a vital maintenance system for the most precise movements

www.cell.com/current-biol...

Neural circuits encode prior knowledge of temporal statistics - Nature Neuroscience This study shows that cerebellar circuits learn and encode prior probabilities of event timing. Cell-type-specific neural activity reflects environmental statistics and guides predictive motor behavio...

Neural circuits encode prior knowledge of temporal statistics

www.nature.com/articles/s41...

The ISPSM is happy to announce a double book symposium on: Kate Nave's A Drive to Survive & Jakob Hohwy's The Self-Evidencing Agent
May 12, H 10:00 CEST
Subscription form Here: forms.gle/NGkFaVYHS7Lk...
#philmind #philsci #philsky #philpsy #neurosky #neuroskyence

Fave things, one title #interoception 🫁🧠❤️

🎉 Excited to share our publication in PNAS! 🎉
What happens when our stream of consciousness turns towards the body? Our fMRI study of 536 individuals finds that 'body-wandering' is associated with patterns of brain connectivity, physiology, affect, and mental health:
www.pnas.org/doi/full/10....

Interoceptive ability is uncorrelated across respiratory and cardiac axes in a large scale psychophysical study - Communications Psychology Bayesian psychophysical modelling of cardiac and respiratory interoception (N=241) showed no cross-domain associations in sensitivity, precision, or metacognition, indicating that interoceptive perfor...

Excited to share that our work on organ-specific interoception is now published in Communications Psychology!
www.nature.com/articles/s44...
@micahgallen.com @the-ecg.org

1/8 New preprint alert!

How are signals from the heart encoded in the brain?
What could be the functional implications of cardioception?

We found that neurons in the posterior insular cortex are precisely tuned to heartbeats, and that this cardio-insular coupling supports emotion coding in mice.

Excited to announce that Prof. Alicia Juarrero just joined the fantastic line-up of Keynote speakers for the "Beyond Neuro-Computationalism" workshop.
CFA here: www.uantwerpen.be/en/research-...
#philmind #philsci #philsky #philpsy #neurosky #neuroskyence

Living systematic reviews are an amazing idea, as the evidence keep evolving, so should the review. However, there is a crucial issue to be tackled: how do we build a robust community updating the review over time? Which are the incentives? Which are the "social tools" available?

Intestinal interoceptive dysfunction drives age-associated cognitive decline - Nature Age-related microbiome changes increase medium-chain fatty acid-producing bacteria, driving GPR84-mediated myeloid inflammation, impaired vagal signalling and hippocampal dysfunction; targeting this g...

Remarkable study from Christoph Thaiss and colleagues demonstrating a lifespan impact of a microbiome-vagal-CNS pathway dysfunction of gut interoception

www.nature.com/articles/s41...

'bad metaphysical hangover' on the other hand...

A Predictive Processing Framework for Joint Action and Communication Humans act together to achieve feats they could never achieve alone and communicate to ensure alignment of meaning and understanding across different …

www.sciencedirect.com/science/arti...

🚨Preprint! “Bayesian surprise tracks the strength of perceptual insight” - Work with @lindedomingo.bsky.social & @gonzalezgarcia.bsky.social

Ever wondered what factors influence the subjective experience of suddenly understanding a previously unclear input?

Click below:
doi.org/10.64898/202...

Orbitofrontal cortex drives predictive filtering of sensory responses - Nature Neuroscience Top-down projections from the orbitofrontal cortex carry predictive signals that grow with sound experience and suppress the auditory cortex via inhibitory circuits, revealing a predictive mechanism f...

Orbitofrontal cortex drives predictive filtering of sensory responses

www.nature.com/articles/s41...

#neuroskyence

Happy to share our new Opinion now out in @cp-trendsneuro.bsky.social, with Catherine Tallon-Baudry and Anthony Clément!

A dual-function framework of interoception: the information and coordination modes of interoceptive signaling

Full access:
authors.elsevier.com/a/1miOLbotqB...

#neuroskyence

what is thinking, actually?

Seems an ideal discussion paper for many of us here who experimentally nudge around the margins of thought while assuming people are doing it

🧠🤣 #neuroskyence

Spatial Filters—In Search of the Virtual Electrode A spatial filter combines signals from multiple sensors to create a virtual channel that emphasizes specific brain activity while reducing interference. Spatial filters range from simple, fixed config...

Spatial Filters—In Search of the Virtual Electrode

www.jneurosci.org/content/46/7...

Beyond metaphor: quantitative reconstruction of Waddington landscape and exploration of cellular behavior Abstract. Originally proposed as a conceptual metaphor, the Waddington landscape was used to illustrate the directional nature of embryonic development and

Beyond metaphor: quantitative reconstruction of Waddington's landscape and exploration of cellular behavior academic.oup.com/bib/article/... - really nice review of how big data and new computational methods and reviving an old conceptual framework

Mathematical Methods in Computational Neuroscience Summer school in Eresfjord, Norway (July 8th - 26th, 2024)

Applications are now open for the summer school: 𝐌𝐚𝐭𝐡𝐞𝐦𝐚𝐭𝐢𝐜𝐚𝐥 𝐌𝐞𝐭𝐡𝐨𝐝𝐬 𝐢𝐧 𝐂𝐨𝐦𝐩𝐮𝐭𝐚𝐭𝐢𝐨𝐧𝐚𝐥 𝐍𝐞𝐮𝐫𝐨𝐬𝐜𝐢𝐞𝐧𝐜𝐞

🧠 Apply before March 15: www.compneuronrsn.org

📍 Located in beautiful Eresfjord 🇳🇴
🗓️ Between July 6-24

Supported by the @kavlifoundation.org
In collaboration with @kavlintnu.bsky.social

'Why the polyvagal theory is untenable. An international expert evaluation of the polyvagal theory and commentary upon Porges, S.W. (2025). Polyvagal theory: current status, clinical applications, and future directions.'

Interested in cortical wave dynamics? Check out our review on the physics, physiology, and psychology of cortical waves led by J Cruddas with @jchrispang.bsky.social, out now in
@cp-neuron.bsky.social:

www.sciencedirect.com/science/arti...

NYAS Publications From birth, respiration constitutes an intrinsic rhythm. We suggest that vocalizations and bodily movements are interactively coordinated with this respiratory rhythm, providing a temporal framework ...

Toward a Fuller Integration of Respiratory Rhythms Into Research on Infant Vocal and Motor Development

From @susfuchs.bsky.social Elina Rubertus, Laura L. Koenig, Aude Noiray

nyaspubs.onlinelibrary.wiley.com/doi/10.1111/...

Diagram showing four phases of methodological research (Theory, Exploration, Systematic Comparison, Evidence Synthesis) with an arrow indicating that preregistration usefulness increases from early to late phases. Each phase lists its aim, elements, outcome, and an example from factor retention research.

Does it make sense to preregister simulation studies?
This question has sparked a lot of debate.

▶️We* work through the why, when, and how
▶️We discuss different phases of methodological research to clarify where preregistration might (or might not) add value

📝 Preprint: doi.org/10.31234/osf...

The Impact of Non-Neural Sources on Aperiodic EEG Activity

www.biorxiv.org/content/10.6...