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Posts by Manvendra Singh

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Grossesse : une nouvelle piste pour détecter la pré-éclampsie plus tôt Encore difficile à anticiper, la pré-éclampsie reste une complication redoutée de la grossesse. Mais une récente avancée scientifique, menée notamment par l’Institut Imagine, ouvre la voie à un dépist...

🔥Feeling so thrilled to see a story of our recent paper on Transposons and Preeclampsia on the front page of Femina Magazine. #TEsky
www.femina.fr/article/gros...

5 days ago 0 0 0 0
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🧬 We are LIVE at the weekly MAGIC seminar at Imagine! Kicking us off is @joshwaterfall.bsky.social (@institutcurie.bsky.social ) presenting "Improved Out of Distribution Embeddings with AutoEncoders." Fascinating insights into computational biology! 🧵

1 week ago 6 3 1 0
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🧫 Wrapping up today's fantastic MAGIC seminar is @manusingh.bsky.social (@inem-necker.bsky.social). His talk: "Single-Cell Mapping of the Reawakening of Ancient Foes in Ageing Disorders." A deep dive into the molecular & cellular mechanisms of Alzheimer. Thanks to all speakers & see you next week! 🧪

1 week ago 4 3 0 0

I will ! I am gonna read it in train today🙏🏽

1 month ago 1 1 0 2
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Transposon Ecology and the Octopus Genome Transposable elements (TEs) are mobile strands of DNA prevalent in octopus genomes. TE activity in the octopus brain might reflect an organism-beneficial role in cognition; or could be a deleterious ...

#TEsky Another paper in our TE ecology exploration of the Octopus out in BioEssays. Types of niches for TEs and what that could mean for their expression in neural tissue doi.org/10.1002/bies...

1 month ago 13 6 2 0

Lovely Tyler. Super interesting

1 month ago 0 0 1 0
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Pluripotent stem-cell-based screening uncovers sildenafil as a mitochondrial disease therapy Mitochondrial disease encompasses inherited disorders affecting mitochondrial function. A severe and untreatable form of mitochondrial disease is Leig…

Our collaborative work is out now in CELL @cellpress.bsky.social

We sugggest sildenafil as a repurposable drug for mitochondrial disease.

A clinical trial is planned to start later this year.

Thanks to collaborators, funders, and patient organizations!

www.sciencedirect.com/science/arti...

1 month ago 35 10 5 1

Phenomenal work! Congratulations Alesandro🙏🏽

1 month ago 1 0 1 0
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Ancient viral DNA drives preeclampsia in pregnancy Researchers have uncovered the molecular details of how ancient viral DNA controls a gene linked to preeclampsia. The study, published in “Genome Biology,” builds on previous research and may lead to a diagnostic test to identify preeclampsia risk much earlier.

Ancient viral DNA drives preeclampsia in pregnancy | Max Delbrück Center www.mdc-berlin.de/news/news/an...

1 month ago 1 2 0 0
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Happy Women’s Day 🎊🎊😊to all of us and especially three outstanding women leading science at the highest level around our Necker Campus.

Fabiola, Bana, and Yasmine, the directors of Necker, IMAGINE and Pasteur Institutes, respectively. Proud to be part of this cluster.

1 month ago 1 0 0 0

Except the Jasprit Bumrah. He found a paradise even on this dead pitch :)

1 month ago 1 0 1 0
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Happy Holi everyone 🌈
A festival where poetry meets science as every color carries meaning, every wavelength shapes how we see the world. Train your eyes with colors and your heart with kindness.

May peace, harmony, and love spread across every spectrum of humanity.

1 month ago 2 0 0 0
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In a mouse model of Primrose syndrome, rhEPO reverses. This is preclinical & could be the first tangible therapeutic path.

Huge thanks to Justus, @cakirumut.bsky.social , Klaus and Hannelore and to an amazing team.

DOI: 10.1172/jci.insight.200021

#RareDisease #Neurobiology #TranslationalResearch

1 month ago 1 0 0 0

Stranded due to airspace closures. Major grant + revision deadlines piling up.

War reaches far beyond borders — even those who think they’re uninvolved feel it.

And yet this inconvenience is nothing compared to what others are enduring.

Please choose peace. Humanity first.

1 month ago 0 0 0 0
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Suggesting a potential therapy for these autism-related symptoms and intellectual disability…

This issue’s Cover features work by Hannelore Ehrenreich & team on the improvement of Primose syndrome traits in mice following erythropoietin treatment: doi.org/10.1172/jci....

1 month ago 2 1 0 1

So thrilled to have our research as a cover feature at @insight.jci.org, showing recombinant human Erythropoetin can compensate for the loss of function caused by the genetic mutation.
I hope this research will age well.
Thanks Hannelore, Klaus, @cakirumut.bsky.social , Justus and ex-colleagues

1 month ago 2 1 0 0
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The $100 whole human genome sequence finally reached!
www.sandiegouniontribune.com/2026/02/19/s...

2 months ago 257 77 12 11
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Ancient co-option of LTR retrotransposons as yeast centromeres - Nature Evolutionarily related ‘proto-point’ centromeres providing resolution to the evolutionary origins of point centromeres are identified in yeast, and comparison shows they evolved in an ancestor with re...

Our paper is now out in Nature:

“Ancient co-option of LTR retrotransposons as yeast centromeres”

www.nature.com/articles/s41...

A short thread on how retrotransposons helped give rise to yeast point centromeres.

1/14

2 months ago 234 120 9 10

Phenomenal story, journey and a great thread. Thanks for sharing. Kudos to the entire team.

2 months ago 1 0 0 0
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Thanks a lot 🙏, I can't wait to see you!

2 months ago 0 0 0 0

Many Congratulations @retrogenomics.bsky.social , very well deserved and well earned. 🙏🏽

2 months ago 0 0 1 0

I love these recipes 🤗

2 months ago 1 0 0 1

Such a great award and the reward too. Very well deserved @m-vincendeau.bsky.social , Many congratulations and hopefully many more to come ☺️
Keep cementing the #TEsky up above and high.

2 months ago 4 0 1 0

Incredible article and resource too. Congratulations @kaessmannlab.bsky.social

2 months ago 4 0 1 0

🙏 Thanks a lot Marianne. It was totally my pride and pleasure

2 months ago 0 0 0 0

Lucky you 🤗🤗

2 months ago 1 0 0 0
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Gave a talk at @institutcurie.bsky.social on Friday and honestly… it felt unreal. Speaking in the same place where Marie Curie carried out her radiation experiments reminds how long science lasts beyond us.
Thnks Elena Zueva, @mburbage.bsky.social , Sebastian Amigorena, Josh Waterfall and Lorena 🙏🏽

2 months ago 4 0 0 1

Can’t wait Mariana. You’ll rock here

3 months ago 1 0 0 0

Congratulations and all the best

3 months ago 1 0 1 0
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Psoriasis: Unraveling the Causes of Chronic Itching In psoriasis and other inflammatory skin diseases, chronic itching or pruritus is a particularly distressing symptom for patients which remains difficult to treat today. Scientists at the Institut Pas...

🧠🧬 Psoriasis: Unraveling the Causes of Chronic Itching

@belkaidlab.bsky.social and Institut Pasteur researchers show that an excessive immune response to skin microbes activates the IL‑17A pathway in nerves, leading to chronic itch and nerve regrowth.

👉 www.pasteur.fr/en/home/rese...

3 months ago 11 6 0 0