Wordle 1,762 X/6

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I went too scientific for this one and got the wrong consonant…

Structural insights into metallocluster trafficking in the nitrogenase assembly scaffold NifEN - Nature Catalysis Structural insights into the assembly of the complex nitrogenase cofactor are scarce. Now, cryo-EM and AlphaFold analyses of NifEN, which converts the precursor (L-cluster) to a mature cofactor (M-clu...

Finally, the group of Marcus Ribbe reports @natcatal.nature.com on how NifEN is a dynamic hub that coordinates L-cluster reception, delivery, and maturation through conformation-gated metallocluster trafficking: www.nature.com/articles/s41...
Hope you'll enjoy the read!

Trafficking of a nitrogenase FeMo-cofactor assembly intermediate - Nature Chemical Biology The maturation of the unique FeMo-cofactor of molybdenum nitrogenase is a multistep process requiring the sequential action of a series of maturase complexes. Here, the authors report on how cryo-elec...

the second, www.nature.com/articles/s41... by the group of Oliver Einsle, combines cryo-EM snapshots and structural modelling of the delivery of the L-cluster handover to NifEN by NifX. There is also a News & Views piece rdcu.be/e93pF by @rhyswg.bsky.social which ties them up together!

Dynamics driving the precursor in NifEN scaffold during nitrogenase FeMo-cofactor assembly - Nature Chemical Biology Nitrogen fixation by nitrogenase requires a metallocofactor built by a dedicated multiprotein machinery. Here, the authors captured structural snapshots of a precursor entering a key maturase, reveali...

Two studies at @natchembio.nature.com focus on the function of NifEN, the scaffold protein that mediates the final stages of cofactor biosynthesis: the first, www.nature.com/articles/s41..., by the group of Yvain Nicolet, reports on the dynamic structural changes it undergoes during its function;

Lots of interest on nitrogenase cofactors assembly across @natureportfolio.nature.com Nitrogenases are enzymes that reduce atmospheric dinitrogen (N2) to ammonia (NH3) so that nitrogen can enter the biosphere. Three studies now focus on NifEN #chembio people: let's dive in!

The planet Saturn is clearly banded in this infrared view, and its rings are glowing. The small bright point at lower left of the planet is the icy satellite Dione. The background is pitch black.

This new #JWST image of Saturn is AWESOME

C’era una volta una gatta…

One can still visit his reconstructed hospital cell where he was imprisoned while in Ferrara (Italy), in the city centre

This never happens to me before, so before it’s too late I’m pinning it here 😎

Par🇮🇹le n°1505 2/6

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This is an interesting remark. Did you find anything in Klingon then?

Locum Associate or Senior Editor Job Title: Locum Associate or Senior Editor (Chemical Biology / Biological Chemistry), Nature Chemistry Company: Nature Portfolio Contract Type: Full-time, Fixed Term (maternity leave cover) Location(...

We're hiring! We're looking for a Locum Editor to cover our chemical biology/biochem. The role can be located in either our London or Pune offices. Planned start date is June 1st. Closing date for applications is Feb 2nd. #chemjobs #chemsky springernature.wd3.myworkdayjobs.com/SpringerNatu...

"Insieme a Giorgio Armani, Krizia, Gianfranco Ferrè, Ottavio Missoni e Gianni Versace, faceva parte di una generazione di stilisti che contribuì a far conoscere e apprezzare la moda italiana in tutto il mondo."

A cell undergoing cell division photographed through a microscope. #CellBiology

A high-angle, nighttime photograph of a quiet residential street in the United Kingdom during a light snowfall. The scene is illuminated by a tall, bright streetlamp in the center, which casts a warm glow over the houses and reveals fine snowflakes falling through the air. In the foreground, a frost-covered lawn and a paved driveway are visible, partially obscured by dark evergreen bushes. A wooden fence runs along the right side of the frame. Across the wet, dark asphalt road, a row of diverse detached and semi-detached houses stands under the night sky. The houses feature a mix of architectural styles, including white pebbledash exteriors, brickwork, and one traditional Tudor-style home with dark timber framing. Thin layers of white snow coat the rooftops, the tops of manicured hedges, and several parked cars along the curbside. The windows of the homes are mostly dark, though one central house has a bright light shining from its front door, casting long shadows across its white driveway. The overall atmosphere is still, cold, and serene.

NG2 light #uksnow. A nice way to end the holidays. Let’s see how it will look like in the morning!

Ho trovato solo alcuni episodi, del 2022: é già finito?

Happy New Year!

No, lo raccomandi?

Ascoltavo Nessun Luogo É Lontano di radio24, ma son episodi giornalieri di ~40 minuti e nn ci stavo dietro. Interessante però, sulla politica estera mondiale

A shot from the Sound of Music, where the kids and fraulein ask the Commander to play and sing a song, with the Baroness in the background.

A Christmas tradition on Italian tv is a showing of Tutti Insieme Appassionatamente, or The Sound Of Music. 🎄

Join us!

Anche io nn lo vedo. Secondo me, il profilo è finito su liste di moderazione ed è stato automaticamente bloccato…

There’s so many of you there this year (including Grant): have a great time!

Qsta me la devi spiegare 😅 compagno è dell’Hertfordshire, che nn è male

Allora c’è qlcs di bello nel Suffolk!

Come join our team! The deadline is December 7, but the application is quick. Only a cover letter, CV, and a short Research Highlight are needed #chemsky #chemjob #chembio

I just saw this thread before seeing your post: bsky.app/profile/josh...
The email is the best!😹

Ah pure l’avvocato! Cose serie! Sicuramente cantina occupata da altri.

La signora ha trovato la cantina?

Disney+ to Allow User-Generated Content Via AI Disney CEO Bob Iger hinted at "productive conversations" with unnamed AI companies that would protect IP but add new features to the studio's flagship streaming service.

And

www.hollywoodreporter.com/business/dig...

Compare and contrast, or two different approaches to AI-generated content: