Jack Szostak "All of these things frighten me, and they should frighten you as well. I made the decision to create a life for myself here, because I viewed this as a place that rewarded determination, hard work, and integrity. It still has a chance to be that place again."
Posts by Alex Schier
With this “Behind the paper” story, I’d like to give special thanks to two remarkable contributors whose generosity made a big difference:
@jialinliu.bsky.social for the scMultiomics data behind the multiomic atlas,
and Guoqiang Yu’s group for sharing ITEC cell tracking, which enabled MERFISH-FATE.
From fate to form: the journey to whole-embryo spatial transcriptomics
In this 'Behind the paper' feature, @yinanwan.bsky.social shares the inside story of an ambitious journey with @schierlab.bsky.social & co.
thenode.biologists.com/from-fate-to...
"We want to see the academic publishing industry change in a way that benefits science, not just profits"
A question I get asked all the time by @dev-journal.bsky.social authors "Why does it cost so much to publish a paper?"
We break down the finances and explain where the money goes
Spoiler: quality publishing takes a village (people + infrastructure)
journals.biologists.com/dev/article/...
Prof. Markus Rüegg and Dr. Judith Reinhard joined the Telebasel studio to talk about progress and the ongoing challenges of the gene therapy they’ve developed to treat LAMA2-related muscular dystrophy, a currently incurable and fatal muscle disease affecting children.
telebasel.ch/sendungen/pu...
It's out! Happy to present ITEC, a semi supervised algorithm with an extremely low error rate that can track cells in files of any size (think Terabytes!). We used it in many organisms, including zebrafish, to study how organs form and linked it to gene expression www.biorxiv.org/content/10.6... +🧪
Embryogenesis in 4D: a developmental atlas for genes and cells 🧪
@schierlab.bsky.social developed a new method (#weMERFISH) that visualizes the activity of hundreds of genes across the entire zebrafish embryo with subcellular resolution.
lnkd.in/eHY5gXDx
@erc.europa.eu @snsf.ch @unibas.ch
How does a tiny cluster of cells become an embryo? Researchers @biozentrum.unibas.ch mapped gene activity across the entire zebrafish embryo, creating a 4D atlas that links gene expression to cell movement & development.
www.unibas.ch/en/News-Even...
Very grateful to everyone who made this work possible. I feel incredibly lucky to have worked with such an amazing team.
Special thanks to: Jakob El Kholtei, KJ Jenie, @mcolomerr.bsky.social, and of course our wonderful collaborator Bogdan Bintu and my mentor @schierlab.bsky.social
Improved version of this earlier preprint. Now with MERFISH-FATE to connect gene expression to morphogenesis. www.biorxiv.org/content/10.1...
Gene expression patterns in zebrafish embryos (6-somite stage; anterior at top).
Very happy to see this out. 👏 @yinanwan.bsky.social
Bogdan Bintu and team.
Whole-embryo spatial transcriptomics at subcellular resolution from gastrulation to organogenesis | free link Science www.science.org/eprint/5MHTM...
TODAY IS THE DAY.
NATIONWIDE rallies in your local city are kicking off today to SAVE SCIENCE, PROTECT HEALTH, and DEFEND DEMOCRACY.
Visit standupforscience.net/march7 to find your local rally!
GET OUT THERE SCIENCE ACTIVISTS!!!
#March7
#standupforscience
#science
#rally
#savescience
The Summer Call for our prestigious, fully funded #PhDFellowships is now open to talented early-career scientists worldwide.
🔬 Rotation-based program
🌍 International community
🗓 Apply by May 8, 2026
Apply now and join a leading life sciences institute!
www.biozentrum.unibas.ch/phd/internat...
One more week to finalize your applications for the 2026 MBL zebrafish course at Woods Hole!
Application deadline extended to March 9.
Please repost and forward to anyone interested in learning 'everything zebrafish'!
www.mbl.edu/education/ad...
Deadline March 1. Join the new Dietschy Facility for Tissue Science.
www.biozentrum.unibas.ch/open-positio...
Deadline March 1. Join the new Dietschy Facility for Tissue Science.
www.biozentrum.unibas.ch/open-positio...
Deadline March 1. Join the new Dietschy Facility for Tissue Science.
www.biozentrum.unibas.ch/open-positio...
Switching fields or wanting to become an expert in #zebrafish research?
The @mblscience.bsky.social 2026 Zebrafish Development & Genetics course offers a fantastic opportunity to learn from leaders in the field!
Application deadline: March 2
Please spread the word!
www.mbl.edu/education/ad...
Thinking about EZM2026 in Vienna? 🐟
Travel grants are now open for students & ECRs.
7–11 July 2026 | Deadline: March 15
Hope to see many of you there! @ezsociety.bsky.social #zebrafish
FIONA DOETSCH @doetschlab.bsky.social @biozentrum.unibas.ch @unibas.ch is awarded the 2026 Louis-Jeantet Prize for Medicine for discovering the identity of neural stem cells in the adult mammalian brain and for demonstrating that they enable mammals to adapt to specific physiological states.
Best Christmas Card of 2025 award goes out to the @biozentrum.unibas.ch for this incredible building-themed-advent-calendar! Opening a window each day has been fantastic! ❄️☃️😁
We will miss you Madalena and follow your exciting research at MPIDresden@mpi-cbg.de
This past month marked the end of an era at the @schierlab.bsky.social @biozentrum.unibas.ch. It was a meaningful, intense, often challenging, but also incredibly rewarding chapter of my scientific journey. Thank you all in the Schier Lab for the unconditional support and the Schierleading!
🧪An international study led by Prof. Roderick Lim has discovered that nuclear pore complexes—gateways in the nuclear membrane—are not rigid or gel-like as once thought. Instead, their interiors are constantly moving and rearranging. @unibas.ch @snsf.ch 👉
www.biozentrum.unibas.ch/news/detail/...
... and we would love to see you ALL - working with ANY fish model - join us in Vienna for www.ezm2026.org, the biggest fish meeting in 2026! We plan to have a special session 'beyond zebrafish' and would love to include talks representing other fish systems across all sessions. Pls spread the word!
Apply for our Master of Science in Physics of Life – training in cutting-edge research at the interface of physics, mathematics, engineering and life sciences. Scholarships available. Application deadline: 30 November. More: www.biozentrum.unibas.ch/education/de...
@biozentrum.unibas.ch @unibas.ch