Also - preprint alert!
Jeroen Kappelhof is noe on it with his next chapter investigating genetic diversity in Asian Elephant subspecies 🎉
🐘 🧬

bit.ly/3LSF6nH

🥳🎉

special issue of Genetics is out 🥳🥳
functional variant prediction in drosophila with @juliabeets.bsky.social !
doi.org/10.1093/gene...

💪👏👏

The world’s oldest #RNA extracted from #WoollyMammoth: “gives us a completely different picture” YouTube video by SciLifeLab

The world’s oldest #RNA extracted from #WoollyMammoth: “gives us a completely different picture” ↓ 🧪⚒️

Woolly mammoth preserved in the Siberian permafrost for nearly 40,000 years sequenced. 🖥️ 🧬
www.youtube.com/watch?v=tHQv...

Weekend reading:
www.scilifelab.se/news/worlds-...

so proud of my former phd supervisor and former colleague (coincidentally now current colleagues again kinda!) who together with their colleagues published these cool results in JAMA oncology! 👏 @scilifelab.se

doi.org/10.1001/jamaoncol.2025.4480

🦴🧬🦴🧬🦴

Abstract submission is now open for the 1st International Conference on Palaeogenomics!

June 23–26 2026, in Stockholm.

Join researchers from across the field for 4 days and >100 talks (+ poster sessions)!

Submit abstracts here 👉
icp2026.palaeogenomics.org/abstracts/

Deadline: Nov 30th

not with me on it, but if you are curious about workflows for non model organisms that can help in quantifying high impact variants and hopefully genetic load, find the poster P03.060 today - the one with the boaring pig in the bottom 🫡
#ESEB2025

(sorry for the shitty contrast in header :( )

The @cpgsthlm.bsky.social gang at #eseb2025 in Barcelona 🇪🇸 Big museomics day with bears, bison & bumblebees 🐻🐮🐝🧬

read about is here:

#ESEB2025
museomics:
lastly, please help @alexgilardet.bsky.social help George ask Love to invest in automatic robots to help in the lab 💪

or follow the new methods and validations developed by Alex that he is explaining today in his talk!

(sorry for the rainbow effect)
@cpgsthlm.bsky.social

#ESEB2025
museumics:
followed up by our own bumblebee guy Michael Mitschke, talking about insect decline in cuties like bombus pascorum ik Sweden 🐝
@cpgsthlm.bsky.social

#ESEB2025
great talks in the museomics session, including @amandalindahl.bsky.social giving a great talk on her first (!!) conference 👏 🐻

interested in deleteuorius mutations and genetic load quantification in non model organisms?

visit me on Thursday 💪 🧬 🐗
poster P03.060

#ESEB2025

first day of @eseb2025.bsky.social in Barcelona is off to a great start !

first with a deep time mammoth talk with @knmoreland.bsky.social , then a little chat with @ergabiodiv.bsky.social ,

followed by some ecology and then some duplications on the schedule.

I am starting a computational lab at LIOS, Riga, Latvia, and going to recruit a few people. Please DM if you are interested in a postdoc or PhD position in my Metabolic Research Group within the TARGETWISE project. I can highly recommend Riga, it is a beautiful city with very good living conditions.

a poster for batman caped crusader shows a man in a suit and tie asking should i be worried ALT: a poster for batman caped crusader shows a man in a suit and tie asking should i be worried

that feeling when your prediction model accuracy including 10 fold cross validation turns out surprisingly well but you dont trust it and are afraid it is overfitted...

Postdoctoral Position in Wildlife Palaeogenomics!

Come join us in beautiful Stockholm!

su.varbi.com/en/what:job/...

That feeling when you are in a focus group meeting discussing eDNA to measure and monitor biodiversity and pros and cons, and Amanda's review exploring exactly that pops up in your feed
💪🎉
congrats @amandalindahl.bsky.social for your first publication!
#biodiversity #PhD

Predicting the functional impact of single nucleotide variants in Drosophila melanogaster with FlyCADD Understanding how genetic variants drive phenotypic differences is a major challenge in molecular biology. Single nucleotide polymorphisms form the vast majority of genetic variation and play critical...

Preprint alert: FlyCADD! 🧬

Excited to share FlyCADD: impact prediction tool scoring the functional impact of any single nucleotide variant across the entire Drosophila melanogaster genome, to distinguish causal from neutral SNPs

www.biorxiv.org/content/10.1...

**whole genome alignment... 🧬😊

based on the mouse, pig and chicken CADD work from Wageningen University and Research she now includes several hundred annotation features to score variants while also presenting some use-cases and validation in the melanogaster system

yayy! 🎉
#phd #genetics #evolution

by reworking the whole framework, using a recently available large drosophila while genome alignment, she now has genome wide impact prediction scores for melanogaster

Predicting the functional impact of single nucleotide variants in Drosophila melanogaster with FlyCADD Understanding how genetic variants drive phenotypic differences is a major challenge in molecular biology. Single nucleotide polymorphisms form the vast majority of genetic variation and play critical...

pre-print alert! my Dutch colleague @juliabeets.bsky.social just put her first PhD chapter out as preprint !

she has reworked the Kircher et al 2014 CADD for drosophila 💪

bit.ly/FlyCADD

Congrats to Samantha López Clinton for the successful half-time PhD seminar 🎉

A photo of Alexandre Gilardet presenting his research during the Licentiate defense.

A photo of Chenyu Jin presenting her research during the half-time PhD seminar.

Congrats to our students @alexgilardet.bsky.social and Chenyu Jin for their successful Licentiate defense and half-time PhD seminar! 🎉

happy birthday @cpgsthlm.bsky.social 🥳🎉🥳

A High‐Throughput Ancient DNA Extraction Method for Large‐Scale Sample Screening Large-scale DNA screening of palaeontological and archaeological collections remains a limiting and costly factor for ancient DNA studies. Several DNA extraction protocols are routinely used in ancie...

A high-throughput aDNA extraction method for large-scale sample screening 🦣🦬🧬
onlinelibrary.wiley.com/doi/10.1111/...

I attended last year, and highly recommend it - even as a postdoc having a long(er) background in popgen!

After not having been active in popgen during my PhD, this course was the perfect mix of freshening up old knowledge and getting the latest state-of-the-art solutions and updates.

happy to have just shared my latest results at the @scilifelab.se #evolution conference in Linköping 💪💪