Always appreciative of our funding sources: VeloSano and the NCI. Excited to tackle these revisions.

Platelets drive immune suppression and glioblastoma growth in a sex-dependent manner via PAR4 signaling Sex differences in cancer outcomes, including glioblastoma (GBM), are shaped by biological, hormonal, and immune factors, influencing disease progression, treatment responses, survival, and the tumor ...

Excited to share our new preprint. We are only beginning to understand the role of platelets in sex-biased immunity in glioblastoma. Grateful for awesome colleagues, collaborators and the fantastic mentorship from @gbm-maestro.bsky.social and @2scottish.bsky.social

www.biorxiv.org/content/10.1...

Thank you ISTH for the oppurtunity to present our work on sex biased platelet mediated immune surpression in GBM. A great few days of inspiring discussion with old and new friends. So much work to be done, but until next time. #ISTH

Amazing times — Exciting science, great discussions, & even better company. It wasn’t just about cutting-edge research; it was about forming lasting friendships w/ people who share the same passion. Grateful to be part of such an inspiring community. Looking forward to the next one in Italy!

Thousands “Stand Up for Science” across the country Including Nobel laureates, climate researchers, and parents of kids saved by groundbreaking drugs.

Thousands “Stand Up for Science” Across the Country

Including Nobel laureates, climate researchers, and parents of kids saved by groundbreaking drugs.

www.motherjones.com/politics/202...

Brilliant science and discussions this past week at the Gordon Research Conference and Seminar on Platelets and Megacaryoctes. Grateful to have been given the opportunity to talk about my work. Also, great talks by two of my closest mentors and collaborators. @2scottish.bsky.social @EviStavrou

LCK-mutant mice help define the role of LCK–co-receptor association in T cell development and immune responses @sciimmunology.bsky.social
www.science.org/doi/10.1126/...

Revealed: NIH research grants still frozen despite lawsuits challenging Trump order The Trump administration is exploiting a loophole to keep a funding freeze in place, leaving researchers in limbo.

Almost all grant-review meetings under Trump 2.0 remain suspended at the US National Institutes of Health (NIH), preventing the world’s largest public funder of biomedical research from spending much of its US$47 billion annual budget.


https://go.nature.com/4gM6oW4

Do you care about equity in science education? Do you want to diversify the professoriate?

Follow @riseupneo.bsky.social to learn more about what we are doing to transform public education in #Cleveland and/or donate to the cause! 🧪

Roughly 9% of NIH employees fired yesterday - rumors are IC directors may be next. Please call your senators and representatives!

@hhmijanelia.bsky.social researchers led by the Spruston Lab have systematically tracked the activity of thousands of neurons over days & weeks during learning activities. They described, step by step, how cognitive maps form in the brain’s hippocampus – a region responsible for learning and memory.

A useful source if you want some good information about NIH accomplishments

www.nih.gov/research-tra....

@gbm-maestro.bsky.social & team discover glioblastoma tumors produce spermidine and drive tumor progression by inducing T cell death: https://www.jci.org/articles/view/177824

Copied over from that other platform from Ankur Singh: x.com/Dr_ASingh/st...

Defying defiance to the laws. Good for NIH!

To my friends and colleagues at UAB, IU, UF, FSU, UL, WashU, OSU, CWRU, etc, etc. Call both your senators and your representative. They listen. Emphasize the direct economic impact of NIH research, and the indirect impacts on pharmaceutical/biotech. Underscore its relevance to national security.

It was a team effort working with two talented med students to co-author this brief report @alan__cr7 @austin_kennemer and great getting feedback from mentors and experts in the field @gbm-maestro.bsky.social @2scottish.bsky.social @alokkhorana.bsky.social

VTE incidence shortens survival in IDH-WT glioblastoma Abstract: Background: Venous thromboembolisms (VTEs) are the second leading cause of death in cancer patients. While previous analyses have demonstrated VTE rates are greater in GBM patients using sma...

Checkout our pre-print where we conducted a large scale clinical analysis looking at VTE rates in GBM. Excited to share mechanistic work in the near future showing how thrombosis drives GBM progression.

www.medrxiv.org/content/10.1...

Great time celebrating the holidays at our annual holiday party @gbm-maestro.bsky.social @oconnor-lab.bsky.social @emulkearns.bsky.social

Ageing of stem cells reduces their capacity to form tumors by reprogramming iron homeostasis
www.nature.com/articles/s41...
www.nature.com/articles/d41...

With grace and gratitude, Happy Thanksgiving to you and your loved ones!

Please help me spread the word about this amazing two-year pre-doc opportunity. Research with faculty is optional. Get paid to take classes that prepare you for PhD. Deadline 11/15: stern.nyu.edu/programs-adm...

Age-related decline in CD8+ tissue resident memory T cells compromises antitumor immunity - Nature Aging Exploring how aging compromises antitumor immunity, the authors reveal an age-related impairment of cytotoxic CD8+ TRM cells in mouse tumor models and clinical samples. They implicate BFAR signaling a...

Age-related decline in CD8+ tissue resident memory T cells compromises antitumor immunity
www.nature.com/articles/s43...

Thank you to everyone who made #SNO2024 a successful event! 🙌 From inspiring sessions to invaluable connections, we’re proud to advance the field of neuro-oncology together. 🌟

Let’s close with a commitment to innovation and collaboration. Safe travels, and see you in Hawaii #SNO2025!

Great time and good discussion with brilliant scientists at SNO2024. Already looking forward to next years meeting! @neuroonc.bsky.social @gbm-maestro.bsky.social @oconnor-lab.bsky.social @dbayik.bsky.social