This year marks 10 years of #IDBugBowl!

The killing of Alex Pretti is a heartbreaking tragedy. It should also be a wake-up call to every American, regardless of party, that many of our core values as a nation are increasingly under assault.

Also, may I say that I don’t agree with people saying ICE and CBP need “more training.” They’re doing exactly what this administration has trained them to—impose a reign of fear in blue cities. They don’t need more training. They need to be ripped up root and branch.

Alex Pretti was a colleague at the VA. We hired him to recruit for our trial. He became an ICU nurse- I lover working with him. He was a good kind person who lived to help and these fuckers executed him.

White. Hot. Rage.

ICE detains 5-year old Minnesota boy; lawyer says agents used him as ‘bait’ The Columbia Heights school district says federal agents have detained four children in their district. School officials and a lawyer for the family say agents used 5-year-old Liam Conejo Ramo as “bai...

The Columbia Heights school district says ICE detained four of its students, including a 5-year-old boy, as "bait" to draw out family members.

Scoop: The leaked protocol of the CDC-funded Hepatitis B vaccine trial in Guinea-Bissau. “This is another Tuskegee.” The protocol reveals that the trial will withhold the Hepatitis B birth dose from thousands—without placebos, without universal maternal screening, and with endpoints critics call indefensible.

We have the CDC-funded Hepatitis Vaccine trial in Guinea-Bissau protocol.

It’s worse than you thought.

Check it out, first in Inside Medicine…

with @pauloffit.bsky.social David Boulware and others.

insidemedicine.substack.com/p/scoop-the-...

Panel A shows KM curve showing no difference in 6 month overall survival between treatment arms. Panel B shows the difference between the high-dose group and the standard-dose group in survival over time. Panel C and D show overlapping KM curves for 6M survival in HIV positive and HIV negative participants, respectively

Trial of High-Dose Oral Rifampin in Adults with Tuberculous Meningitis

Congratulations to David Meya, Fiona Cresswell, @natebahrid.bsky.social @drboulware.bsky.social & co on this important trial

No mortality benefit to high dose rifampin in adults with TB meningitis

www.nejm.org/doi/full/10....

If ACIP chooses to ignore evidence, when it comes to vaccines, parents and clinicians must ignore ACIP and look to those who continue to offer data-based guidance, especially our medical societies.

A "JAMA" article, published online December 3, 2025, titled "Universal Hepatitis B Vaccination at Birth—Risks of Revising the Recommendation" by Michael S. Abers et al., discusses ACIP's review and a possible vote to eliminate the birth dose recommendation.

💬Viewpoint: Eliminating universal hepatitis B birth dose vaccination risks an estimated 8% increase in annual perinatal #HepatitisB infections in the US, increasing preventable chronic disease burden. ja.ma/3Me0zHh

Vaccine Safety MENU V For Everyone NOV. 19, 2025 KEY POINTS • The claim "vaccines do not cause autism" is not an evidence-based claim because studies have not ruled out the possibility that infant vaccines cause autism. • Studies supporting a link have been ignored by health authorities. • HHS has launched a comprehensive assessment of the causes of autism, including investigations on plausible biologic mechanisms and potential causal links.

The U.S. government is now inarguably spreading medical disinformation that is going to kill babies preferentially.

Period.

This is an INTOLERABLE. UNPRECEDENTED. DANGEROUS. ATTACK. ON ALL OF US.

Getting ready for #IDBugBowl @idweek.bsky.social Hope to see y’alll this afternoon. Come and cheer ur team UAB CCF ThomasJefferson and our international team Calcutta Troo Med #IDWeek2025 #IDSky

Get ready to rumble! Teams from the Cleveland Clinic Foundation, University of Alabama at Birmingham, Thomas Jefferson University Hospital, and the Calcutta School of Tropical Medicine compete TODAY at 4:30PM ET in Ballroom (Hall B1) for the #IDBugBowl trophy! 🏆

Trump Administration Lays Off Dozens of C.D.C. Officials

Those fired include the staff of the MMWR, our major source of information on outbreaks and guidelines, EIS, our disease investigators, and many experts. We are not equipped AT ALL to handle another outbreak or at this rate, any infectious disease…

www.nytimes.com/2025/10/11/u...

Screenshot of Truth Social post by Donald J. Trump (@realDonaldTrump) dated 9/26/25, 9:45 AM. The post reads: ‘Pregnant Women, DON’T USE TYLENOL UNLESS ABSOLUTELY NECESSARY, DON’T GIVE TYLENOL TO YOUR YOUNG CHILD FOR VIRTUALLY ANY REASON, BREAK UP THE MMR SHOT INTO THREE TOTALLY SEPARATE SHOTS (NOT MIXED!), TAKE CHICKEN P SHOT SEPARATELY, TAKE HEPATITIS B SHOT AT 12 YEARS OLD, OR OLDER, AND, IMPORTANTLY, TAKE VACCINE IN 5 SEPARATE MEDICAL VISITS! President DJT’

We have a vaccine schedule built on decades of rigorous research by actual medical experts. Trump’s counter-proposal? Trust his gut. What could possibly go wrong when the president cosplays as a pediatrician?

He’s putting real children at risk from diseases we know how to prevent for no reason.

Checking on on ACIP; "at what point should low uptake factor into out decisions" (from one of the new ACIP members working hard to drive that COVID vaccination rate lower. Self-fulfilling prophecy)

I watched the 1st meeting day of RFK Jr’s handpicked committee of vaccine advisors. It was utterly depressing. 1/

I'm watching the ACIP meeting. #Follow along for updates.
The committee will vote on whether to delay the hepatitis B vaccine for babies and whether to give the MMR (measles/mumps/rubella) and chickenpox vaccines separately.

RFK Jr. needs to step down now. He is systematically and aggressively making us less safe and more ill pushing aside any brave professional that refuses to go along with his nonsense.

The ID fellows Cup is planning for another game September 15-October 15! Please share the word!

Need some extra help preparing for boards or want to learn more ID content?

The core content is a game including 60 questions targeting knowledge expected for an ID Fellow for the US licensing exam.

As national medical, scientific, public health and patient organizations, we call for the resignation of HHS Secretary Robert F. Kennedy Jr. to ensure the health of the American people.

Our statement: https://bit.ly/45LeJHi

A clinical practice guideline for tuberculous meningitis Tuberculous meningitis is the most severe form of tuberculosis, causing death or disability in around half of those affected. There are no up-to-date international guidelines defining its optimal mana...

A clinical practice guideline for tuberculous meningitis

Tuberculous Meningitis International Research Consortium

www.thelancet.com/journals/lan... 🔒

Dalbavancin for Treatment of Staphylococcus aureus Bacteremia This clinical trial compares the efficacy and safety of dalbavancin vs standard therapy for completion of treatment of complicated Staphylococcus aureus bacteremia in hospitalized patients.

Happy DOTS Day, to those who celebrate. jamanetwork.com/journals/jam...

They recovered over 180 bullet shells at the CDC. Debris from shattered glass is still being cleaned up. I am completely stunned at how quickly the news cycle has moved on. This was an act of terrorism targeting public health experts, and the response seems to be a collective shrug.

Lack of Association Between Histoplasma Urine Antigen Values and Clinical Response in Persons without HIV AbstractBackground. Histoplasma urine antigen detection, a valuable diagnostic tool, is often used to monitor response to antifungal therapy, but persisten

Lack of Association Between Histoplasma Urine Antigen Values and Clinical Response in Persons without HIV

Marisa Miceli and colleagues

academic.oup.com/ofid/advance...

When you strip away humanity

🚨BREAKING: IDSA, along with AAP, APHA, ACP and others, has filed a lawsuit against HHS/Secretary Kennedy to stop unlawful changes to vaccine policy and defend public health.

We refuse to stand by while America’s public health safeguards are torn apart. bit.ly/4lm7UkW

Evaluating the impact of two decades of USAID interventions and projecting the effects of defunding on mortality up to 2030: a retrospective impact evaluation and forecasting analysis USAID funding has significantly contributed to the reduction in adult and child mortality across low-income and middle-income countries over the past two decades. Our estimates show that, unless the a...

Elon Musk casually, and illegally, dismantled USAID. According to a new study in the Lancet, that action will lead to *14 million* premature deaths between 2025 and 2030.

Again: Elon Musk is directly responsible for 14 million coming deaths. 4.5 million will be children.