Out now in Nature Communications!
We show that Dictyostelium vaults associate with ER and NE membranes in situ and encapsulate ribosomes with defined orientations, shining new light on their cellular function! #TeamTomo #TeamMassSpec #ProtistsOnSky
www.nature.com/articles/s41...

Huge congrats Noah, so glad to see this out!!

Do you have a sense of what drives this kind of omission? Malicious intent or simple lack of care?

so glad you got something out of it, thanks for sharing!

🚨🚨🚨JOB ALERT🚨🚨🚨

The Image Analysis Unit at Human Technopole in Milan is recruiting for two positions to join our growing team:

1) Bioimage Analyst
2) Research Software Engineer (RSE)

Read on to learn why one of these two people should be you!

new neighbourhood is a vibe

multidisciplinary doesn’t begin to cover it

I can’t imagine too many people I’d love to work with more than Florian, this is your chance!!

Excited about what’s going on at Mirage, great work!!

Candide Thovex - Les Tufs YouTube video by Candide Thovex

I've been thinking about this for a few days, since I watched it. Candide Thovex might be the greatest skier of his generation. This is an *incredibly* political video, in the best and most noble sense.

1 [Nurse talking to camera] This is usually our busiest time of year at the centre 2 [Show a sign outside a medical institution reading:] Centre for Adults Who Still Can’t Get Their Heads Round Daylight Savings 3 NURSE: We have a spike in admissions when BST starts 4 CONFUSED PATIENT BEING LAID DOWN BY NURSES: Is it forward or back? NURSE: Lie down love 5 We often see the same patients ever year PATIENT: So it’s like… time travel? DOCTOR: No 6 Every year we try to explain BST to them in a fun and memorable way [The patients are sat around a fun show, with people dressed in bunny suits jumping around a giant clock] BUNNY: And now I *spring forward*... 7 [Bunny springs forward one hour on clock] 8 PATIENT WATCHING SHOW: I don’t get it 9 The hardest patients are the Summer Time refusers 10 PATIENT [sat strapped to a chair as a doctor talks to him through a screen, through a tannoy] PATIENT: But why is it better? DOCTOR [talking through microphone]: Because it complicates things. 11 PATIENT: How is that good? DOCTOR: It makes you more tired. 12 DOCTOR [to assistant]: Fetch the cattle prod [Ends]

I think the clocks in UK go back tonight. Or forward. Not sure. Is it forward

Remember this from two months ago? Well, with herculean effort, we helped get those two gay men off the deportation flight to Iran, but they still remain locked in detention. Read more about what's happening now in their cases, and with other Iranians facing deportation.
time.com/article/2026...

Damn, this is awesome! Thanks for sharing 🙌

Call me a luddite I guess but I do in fact kind of die inside any time anyone tells me "ask Claude" when I ask them for advice about how to do something.

As if teaching one another was just about passing 1 packet of knowledge from one brain to the next 😵‍💫

napari needs your help! Has napari helped you make cool and groundbreaking discoveries? We'd love to highlight that in our docs. Please tell us about it! You can fill in this survey:

napari.typeform.com/to/vTCKeTKv

and/or, as ever, drop by our chat room or meetings:

napari.org/dev/community/

🙏

“think about whether some of the proprietary license money you’re currently spending could be spent instead on open solutions that would be yours forever, endlessly adaptable, and benefit the entire world. And please get in touch by emailing info@image.coop”

👏 👏 👏
Can’t wait to see where this goes

A man with his 7 year-old son and a 1 year old baby in his lap seated next to a complicated-looking museum exhibit.

One of my father's favorite places in the world was the Exploratorium, a science museum in San Francisco. When he passed away in 1990, my brother and I donated funds to pay for the construction of an exhibit in his memory (on Fourier series). This is me with my two sons at the exhibit in 1990.

1/2

👀

Low resolution cryo-EM map that looks like Cuban's skull

When you still haven't solved the orientation bias of your protein sample #CryoEM

The one science reform we can all agree on, but we're too cowardly to do OR: the long overdue forest fire

Wonderful (and fun!) read from @mastroianni.bsky.social which finishes with a clear answer on how to solve the collective action problem of dismantling scientific publishing

Go Lucien!! Love to see it

looks good, have added to the list! Thanks for the rec :-)

fascinating, looks similar!

I’ve been going through a rough patch and have taken solace in music. This book by William Mathieu is wonderful and illuminating, it builds up harmonic theory from physical principles in a satisfying way - worth spending some time with if intervalic reasoning has always felt a bit opaque/arbitrary

Greece’s Varoufakis Indicted Over Ecstasy Use 36 Years Ago Greece’s former finance minister Yanis Varoufakis has been indicted after admitting on a podcast that he took an ecstasy pill at a rave in Australia in his twenties.

“Putting a party leader on trial for talking about his experiences with substances many decades ago is not an accidental, innocent gaffe. It is a message from a judiciary that closes its eyes to those in power and goes after whoever refuses to bend the knee.”

novaramedia.com/2026/02/27/g...

my pet peeve is the (presumably intentional) incompatibility which leaves the whole email chain present and not collapsible in every message unless you also use outlook… such chaos

Digital products and services are getting worse – but the trend can be reversed A new report from the Norwegian Consumer Council shows how enshittification affects both consumers and society at large. Luckily, it‘s possible to turn the tide.

What a great report by the Norwegian Consumer Council on how digital products and services are getting worse (enshittification)!

Lots of good explanations and examples, but also very actionable with policy recommendations.

reporting back: the answer is quadzilla until further notice. Took a few laps this evening, it’s brutal but manageable. I found a street that replaces the 20+% section with longer at 13%ish 🙃

As of tonight, licenses of trans people across Kansas are being invalidated en masse, enabling the overnight criminalization of an entire group of people for going about our lives. It’s often said you never know when you’re living through history, so let me assure you: that’s what’s happening now.

bundled with office which they already pay for ☹️ agree it’s sad