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Posts by Dan Harki

When @doc-jlmeier.bsky.social tells me to buy merch, I buy.

10 months ago 4 0 0 0
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Mackenzie Wyllie and Laura Hirsch Awarded Doctoral Dissertation Fellowships This prestigious award is bestowed upon the University's most outstanding PhD candidates for their accomplishments in highly significant and innovative research areas.

Congratulations to Mackenzie and Laura!

www.pharmacy.umn.edu/news/mackenz...

11 months ago 5 0 0 0
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Identification of a novel allosteric binding site on the catalytic domain of NF-κB inducing kinase (NIK) NF-κB inducing kinase (NIK) is the central regulatory component of noncanonical NF-κB signalling and has been implicated in a variety of cancers and immune disorders. While NIK has been pursued as a…

Take a look at recent work from Jared J. Anderson and @danharki.bsky.social on the identification of a novel allosteric binding site on the catalytic domain of NF-κB inducing kinase (NIK)🔥⬇

pubs.rsc.org/en/content/a...

📍 @umnmedchem.bsky.social
#chemsky🧪

11 months ago 2 2 0 0
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The #HarkiLab at the #MIKIW2025 meeting at the University of Kansas.

11 months ago 5 0 0 0
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Identification of a novel allosteric binding site on the catalytic domain of NF-κB inducing kinase (NIK) NF-κB inducing kinase (NIK) is the central regulatory component of noncanonical NF-κB signalling and has been implicated in a variety of cancers and immune disorders. While NIK has been pursued as a t...

New work to characterize the ligandability of NIK with an electrophilic fragment. pubs.rsc.org/en/content/a...

1 year ago 3 0 1 0
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Treating a deadly childhood cancer with a sideways approach Degrading a critical scaffolding protein may help treat neuroblastoma

Treating a deadly childhood cancer with a sideways approach: Degrading a critical scaffolding protein may help treat neuroblastoma. cen.acs.org/acs-news/acs... #chemsky🧪 #biosky

1 year ago 14 3 1 0