GeneCentric Presents First Clinical Data for Liquid Biopsy Fragmentomic Technology at AACR Fragmentomic analyses of regulatory DNA regions complemented those of exon regions, enabling better cancer subtyping and showing potential for identifying predictive biomarkers.

GeneCentric Presents First Clinical Data for Liquid Biopsy Fragmentomic Technology at AACR

Roche Provides Updates on Current, Potential Future TB Test Offerings at ESCMID Roche shared early performance data for its new IGRA assay for latent TB detection, while a collaborator detailed efforts to identify non-sputum biomarkers of the disease.

Roche Provides Updates on Current, Potential Future TB Test Offerings at ESCMID

10x Genomics' Atera Launch Puts Pressure on Spatial Biology Competitors The new platform analyzes more than four times the area and twice as many slides per run as the company's Xenium instrument, offering whole-transcriptome profiling with single-cell sensitivity.

10x Genomics' Atera Launch Puts Pressure on Spatial Biology Competitors

With Atera Launch, 10x Genomics Puts Pressure on Spatial Biology Competitors The new platform analyzes more than four times the area and twice as many slides per run as the company's Xenium instrument, offering whole-transcriptome profiling with single-cell sensitivity.

10x Genomics' Atera Launch Puts Pressure on Spatial Biology Competitors

Exact Sciences Broadens Evidence for Oncodetect MRD Test in Early Triple-Negative Breast Cancer The firm's collaborators presented research at AACR showing an association between ctDNA positivity and lack of pathologic complete response after neoadjuvant treatment.

Exact Sciences Broadens Evidence for Oncodetect MRD Test in Early Triple-Negative Breast Cancer

Is It Time for Routine WGS in Cancer Patients? Dutch Researchers Say Yes A study found that in about 10 percent of patients, WGS picked up on clinically actionable information other panels missed.

Is It Time for Routine WGS in Cancer Patients? Dutch Researchers Say Yes

My Gene Counsel, N-Power Paving Path to Precision Cancer Care at Community Practice Through a six-month pilot program at Pacific Cancer Care, the firms are assessing if they can improve guidelines-backed genetic testing and clinical trial enrollment.

My Gene Counsel, N-Power Paving Path to Precision Cancer Care at Community Practice

UCLA Liquid Biopsy DNA Methylation Assay Detecting Cancer, Other Diseases Investigators developed a low-cost noninvasive assay for detecting cancer, organ injury, and other conditions with targeted DNA methylation sequencing on cell-free DNA from blood.

UCLA Team Develops Liquid Biopsy DNA Methylation Assay to Detect Cancer, Other Diseases

UCLA Team Develops Liquid Biopsy DNA Methylation Assay to Detect Cancer, Other Diseases Investigators developed a low-cost noninvasive assay for detecting cancer, organ injury, and other conditions with targeted DNA methylation sequencing on cell-free DNA from blood.

UCLA Team Develops Liquid Biopsy DNA Methylation Assay to Detect Cancer, Other Diseases

Is It Time for Routine WGS in Cancer Patients? Dutch Researchers Say Yes A study found that in about 10 percent of patients, WGS picked up on clinically actionable information other panels missed.

Is It Time for Routine WGS in Cancer Patients? Dutch Researchers Say Yes

Clinicians Offering Early Access to Grail's MCED Test Await Full NHS Trial Readout After Endpoint Miss Ahead of the full data release and FDA regulatory decision, doctors and researchers parse the limitations of clinical trials and debate whether the MCED test is ready for wider implementation.

Clinicians Offering Early Access to Grail's MCED Test Await Full NHS Trial Readout After Endpoint Miss

Australian Ban on Genetic Discrimination by Life Insurers Could Unlock Nationwide DNA Screening Legislation in Australia banning life insurance companies from discriminating against applicants based on genetic testing results is expected to be signed into law imminently.

Australian Ban on Genetic Discrimination by Life Insurers Could Unlock Nationwide DNA Screening

Australian Ban on Genetic Discrimination by Life Insurers Could Unlock Nationwide DNA Screening Legislation in Australia banning life insurance companies from discriminating against applicants based on genetic testing results is expected to be signed into law imminently.

Australian Ban on Genetic Discrimination by Life Insurers Could Unlock Nationwide DNA Screening

ctDNA Useful for Deescalating Breast Cancer Treatment in Older Women, U of Pittsburgh Study Finds The researchers measured ctDNA in women with breast cancer over 70 years of age before beginning endocrine therapy and throughout treatment.

ctDNA Useful for Deescalating Breast Cancer Treatment in Older Women, U of Pittsburgh Study Finds

Lab Industry Weighs Pros and Cons as CMS Ponders Expanding MolDX Program to Address Fraud While the effort could bring new requirements to the reimbursement process, it could also make payments more standardized and predictable.

Lab Industry Weighs Pros and Cons as CMS Ponders Expanding MolDX Program to Address Fraud

Data at ACC suggest a PGx and clinical score developed at University of Florida to predict Plavix adverse events may be broadly useful for deescalating P2Y12 inhibitor treatment. ebx.sh/cU01QU

Women's Health Firms Aim for Earlier Endometriosis Diagnoses Through Menstrual Blood, Multiomics Women's Health Firms Aim for Earlier Endometriosis Diagnoses Through Menstrual Blood, Multiomics

Test developers expect that the research involved in endometriosis assay development will also advance research into other women's health indications.

Ancient DNA Studies Push Dog Domestication Back to Last Ice Age Ancient DNA Studies Push Dog Domestication Back to Last Ice Age

By analyzing genetic ancestry profiles from ancient canid samples, two research teams documented the widespread presence and importance of dogs in Paleolithic Eurasia.

Ancient DNA Studies Push Dog Domestication Back to Last Ice Age By analyzing genetic ancestry profiles from ancient canid samples, two research teams documented the widespread presence and importance of dogs in Paleolithic Eurasia.

Ancient DNA Studies Push Dog Domestication Back to Last Ice Age

Women's Health Firms Aim for Earlier Endometriosis Diagnoses Through Menstrual Blood, Multiomics Women's Health Firms Aim for Earlier Endometriosis Diagnoses Through Menstrual Blood, Multiomics

Test developers expect that the research involved in endometriosis assay development will also advance research into other women's health indications.

Blockchain Offers Transparency, Security for Sharing Genetic Data, but Is No Panacea Blockchain Offers Transparency, Security for Sharing Genetic Data, but Is No Panacea

The cryptocurrency-linked approach could remove bottlenecks in rare disease research and genetic study participation but it's not a one-size-fits-all technology.

Following up on new recommendations, the World Health Organization called for rapid implementation of new tools and approaches. ebx.sh/Dm1MUh

The cryptocurrency-linked approach could remove bottlenecks in rare disease research and genetic study participation but it's not a one-size-fits-all technology. ebx.sh/6U4p5G

Playing the Long Game: At ACMG, Firms Tout Long-Read Offerings for Rare Disease Testing Natera, MyOme, Baylor Genetics, and Variantyx each highlighted their long-read assays at the meeting, while GeneDx is gearing up to join the competition later this year.

Playing the Long Game: At ACMG, Firms Tout Long-Read Offerings for Rare Disease Testing

Meet the Sole Member of WHO's New Class of TB MDx Tests Meet the Sole Member of WHO's New Class of TB MDx Tests

With Pluslife's new system, WHO recently recommended near point-of-care molecular tests using tongue swabs that are expected to lower the costs and improve access to tuberculosis testing.

Newborn Genomic Screening Takes Center Stage at ACMG as Stakeholders Discuss Progress, Concerns Newborn Genomic Screening Takes Center Stage at ACMG as Stakeholders Discuss Progress, Concerns

Clinicians, genetic counselors, and researchers voiced their opinions on newborn genome sequencing, which many believe is the future of newborn screening.

Imaging, Multiomics Study Points to Chronic Traumatic Encephalopathy Risk Factors in Retired Athletes Researchers identified peripheral immune cell changes that accompanied blood-brain barrier disruption in retired athletes at risk of CTE due to repeated head trauma.

Imaging, Multiomics Study Points to Chronic Traumatic Encephalopathy Risk Factors in Retired Athletes

Clinicians, genetic counselors, and researchers voiced their opinions on newborn genome sequencing, which many believe is the future of newborn screening. ebx.sh/da7gjP

With Pluslife's new system, WHO recently recommended near point-of-care molecular tests using tongue swabs. ebx.sh/6h80tZ

The firm's Perturb-seq in vivo CRISPR atlas was created in collaboration with 10x Genomics, NVIDIA, and the Allen Institute for Brain Science. ebx.sh/zcgE0W