New preprint from our lab!

Keep your neutrophils close, but your mast cells closer Immune activity at the cerebrospinal fluid (CSF)–dura–brain interface regulates key functions of brain physiology. In two back-to-back papers, Mamuladze et al. and Kothari et al. show that dural mast ...

Some thoughts on meningeal mast cells inspired by Xinzhong Dong and @jonykipnis.bsky.social recent (and AWESOME) papers.

Lead: @fakesamir.bsky.social

www.cell.com/trends/immun...

Thanks Lorenz!

It's great to see our review printed in @natrevimmunol.nature.com and learn that we made the cover!
BRAIN on the cover of an IMMUNOLOGY journal 😍
review here: www.nature.com/articles/s41...
Congratulations again! @marikovacs.bsky.social @amaia-db.bsky.social @fakesamir.bsky.social

EBV induces CNS homing of B cells attracting inflammatory T cells - Nature Epstein–Barr virus infection generates a neuroinvasive B cell subset, which recruits activated T cells to the central nervous system, promoting multiple sclerosis.

Mechanistic link between EBV and MS! www.nature.com/articles/s41...

very excited for this meeting! #ReThinkNeuroimmunology

Images présentant les manifestations

#StandUpForScience a rassemblé près de 15 000 personnes partout en France. Des scientifiques, équipes, laboratoires, ou des associations citoyennes ont affiché leur soutien par des photographies prises sur leur lieu de réunion ou de travail. Nous les avons assemblées 👇
standupforscience.fr/photos/

Immunologist Yasmine Belkaid: ‘Science is in danger’ The head of France’s Pasteur Institute on Trump’s attacks on health institutions — and what scientists can do to rebuild public trust

I had a rich lunch chat with Yasmine Belkaid, head of France's renowned Pasteur Institute for biomedical research, covering subjects from Trump to gut health.

You can read some FT stories free each month if you register here:

www.ft.com/register

www.ft.com/content/d632... via @financialtimes.com

Call for applications 2025 - Creation of new research groups at the Institut Pasteur - Research The Institut Pasteur launches an international call to recruit new junior research group leaders in the application of cutting-edge transdisciplinary approaches to the exploration of host-microbe, tis...

Two more weeks to apply to join us in Paris !
research.pasteur.fr/en/call/call...

Call for applications 2025 - Creation of new research groups at the Institut Pasteur - Research The Institut Pasteur launches an international call to recruit new junior research group leaders in the application of cutting-edge transdisciplinary approaches to the exploration of host-microbe, tis...

🌟 Join Institut Pasteur as a Junior Research Group Leader 🌟
Explore host-microbe interactions in key areas like vaccinology, infectious diseases, neuro-immunology, and maternal health.

📅 Deadline: Feb 28, 2025 (few weeks left!)

Apply now ⬇️

Thanks for highlighting our work!

And discuss how these routes are used for development and maintenance but become hijacked or modified in aging and pathology. Enjoy!

Specifically, we describe the routes that peripheral immune cells and signals use to shape the brain directly or indirectly.

In this text we discuss how peripheral immune involvement in brain development, function and (anti-aging) maintenance is a feature, not a bug.

Immune control of brain physiology - Nature Reviews Immunology The peripheral immune system communicates with the brain through diverse anatomical routes to shape brain physiology. Here we discuss why such diversity is needed and explore how these routes are leve...

And it's out! The BIC lab presents our new perspective article on "Immune Control of Brain Physiology" - fresh off the press at
@natrevimmunol.bsky.social
nature.com/articles/s41...
wonderful synergy:
@marikovacs.bsky.social
@amaia-db.bsky.social
and @fakesamir.bsky.social