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Posts by Phil Riley

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Breast Arterial Calcification as a Predictor for Future Cardiovascular Events and Mortality: A Systematic Review and Meta-analysis AbstractObjective. Breast arterial calcification (BAC) is a surrogate marker of cardiovascular disease (CVD); however, its associations with incident morta

Peering into your cardiac health via mammography. Another fascinating article.

#CardioSky #MedSky

Breast Arterial Calcification as a Predictor for Future Cardiovascular Events and Mortality: A Systematic Review and Meta-analysis

academic.oup.com/jbi/advance-...

3 days ago 1 0 0 0
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Nicotine and the cardiovascular system: unmasking a global public health threat Abstract. Nicotine-containing products, whether combustible or smokeless, pose a growing threat to cardiovascular (CV) health. While tobacco smoking contin

Nicotine and the cardiovascular system: unmasking a global public health threat

#CardioSky #MedSky

Great article

academic.oup.com/eurheartj/ar...

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❤️❤️❤️

4 days ago 0 0 0 0

Those hyperadrenergic patients with sweaty palms sure do well with nebivolol monotherapy.

Be careful with ABSOLUTES, they bite

1 month ago 0 0 0 0

Whoever gave the title to this event needs to decrease their testosterone intake. #GetOffTheT #NotFightClub

1 month ago 0 0 0 0

1.1 to 1 ??
😉

1 month ago 0 0 0 0
Prior Authorization Requirements and Prescription Fill Patterns Among Patients With Heart Failure

ACC can help. @hmkyale.bsky.social
Your editorial and HF and AI is prescient. Overcoming this unnecessary regulatory hurdle will help millions maximize access to GDMT

www.jacc.org/doi/epdf/10....

1 month ago 0 0 0 0

This is smart 🧠

You don’t know what you can’t see … or, you never catch any fish if you don’t throw out your net

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The stroke risk will be unacceptable when you drill down. Leg PAD doesn’t happen in isolation.

⏱️ the pendulum will swing back

1 month ago 0 0 0 0
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I hope a logical solution like this ends up working and not causing MORE strokes. This is eloquent. ❤️

Current occlusion devices are still too commonly a “square pegs in a round hole”

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Cardiomyopathy Gene Variants and Polygenic Risk Scores in Atrial Fibrillation: Evidence for an Atrial-First Phenotype View all available purchase options and get full access to this article.

❤️ Pathologic CM Genes & incident risk of A-Fib ❤️

⭐️ this is a bigger deal than we currently realize

www.jacc.org/doi/epdf/10....

1 month ago 1 0 0 0
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Weekly Journal Scan: Aspirin and oral anticoagulation—more of a bloody mary than an AQUATIC mix This comment refers to ‘Aspirin in Patients with Chronic Coronary Syndrome Receiving Oral Anticoagulation’, which was published in The New England Journal

Again, No ASPIRIN with DOAC’s

academic.oup.com/eurheartj/ad...

1 month ago 6 1 1 0
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2026 AHA/ACC/ACCP/ACEP/CHEST/SCAI/SHM/SIR/SVM/SVN Guideline for the Evaluation and Management of Acute Pulmonary Embolism in Adults: A Report of the American College of Cardiology/American Heart Assoc... 2026 multisociety guideline for acute pulmonary embolism — evaluation, risk-based management, advanced therapies, and follow-up.

First Ever ACC/AHA Guideline for Pulmonary Embolism Treatment. #CardioSky www.jacc.org/doi/10.1016/...

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I've discussed sending samples to path with our spine surgeon since the manifestation there usually occurs before the cardiomyopathy. #OneSeesWhatOneKnows

2 months ago 1 0 1 0
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The Inherited Basis of Coronary Artery Disease | NEJM Investigations of the genetic basis of coronary artery disease have led to advances in mechanistic insights, therapeutics, prevention, and risk prediction. Indeed, most contemporary medicines for c...

Great Review: The Inherited Basis of CAD | NEJM www.nejm.org/doi/10.1056/...

2 months ago 0 0 0 0

OG article from the UK Biobank

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I bet it’s LVH/HCM in the end

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Importance of Clinical, Laboratory, and Genetic Risk Factors for Incident CAD | Circulation: Genomic and Precision Medicine BACKGROUND: Prior work suggests modifiable cardiovascular risk factors (CRFs) account for 80% to 90% of the risk for incident myocardial infarction. The contributions of genetic and other novel CRFs h...

2025: Polygenic Risk Scores vs all other known Cardiac Risk Factors …

Why aren’t we using this wonderful technology??

www.ahajournals.org/doi/10.1161/...

2 months ago 1 0 0 0
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A multi-ancestry polygenic risk score improves risk prediction for coronary artery disease - Nature Medicine A polygenic risk score for coronary artery disease developed using data from individuals of five different ancestries has increased accuracy across diverse populations.

Later, after statistical analysis, Polygenic Risk Scores from the UK Biobank were tested against the Pooled Cohort Equation (ASCVD Score) and did even better at predicting CV events …

www.nature.com/articles/s41...

2 months ago 1 0 1 0
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Genomic Risk Prediction of Coronary Artery Disease in 480,000 Adults: Implications for Primary Prevention

The original article for Polygenic Risk Scores in ASCVD

www.jacc.org/doi/10.1016/...

2 months ago 1 0 1 0

I bet the difference here is the duration (1 year post-mi) and the specific trials included (CLEAR) vs excluded (LoDoCo2 ??). It will be interesting to see what Dr Ridker says

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Great share! Great lesson … if we listen

2 months ago 1 0 0 0
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Cardiac Risk of NonCardiac Surgery: A Piece of My Mind A video from Kim Eagle (as part of MonteHeart Imaging & Clinical Lectures), posted on Aug 5, 2025.

The lesson: don’t do elective surgery on elderly patients with stroke and/or PAD history on the weekends and holidays. This doesn’t change anything that we know. The pre-op assessment refined by Dr Kim Eagle remains profound.

www.vumedi.com/video/cardia...

2 months ago 0 0 0 0
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Great share!!

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Managing HF Across the Spectrum: This interactive online course offers practical tools to assess risk, classify HF phenotypes, & apply GDMT through an interprofessional care lens. Learn how to tackle pivotal issues in #HFrEF, & more. 👇

🔖 https://bit.ly/3O8JvDp

#ACCEd #CardioSky #MedSky

2 months ago 3 1 0 0
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Effects of Antibiotic Therapy on Outcomes of Patients With Coronary Artery Disease Context Although Chlamydia pneumoniae infection has been associated with the initiation and progression of atherosclerosis, results of clinical trials investigating antichlamydial antibiotics as adjun...

It is cholesterol and inflammation, not infection:

jamanetwork.com/journals/jam...

2 months ago 0 0 0 0
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Antibiotics and Risk of Subsequent First-time Acute Myocardial Infarction Context Increasing evidence supports the hypothesis of a causal association between certain bacterial infections and increased risk of developing acute myocardial infarction. If such a causal associat...

Your framing is wrong. We investigated this back in the 1990’s: jamanetwork.com/journals/jam...

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😉

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Gift link?

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Defining Success of Atrial Fibrillation Ablation: Burden Is the New Black

Somebody help me understand how A-Fib ablation “decreases mortality” when 35% of people with a “Sham procedure” felt better in the SHAM-PVI trial.

Explain it like I’m Five (ELI5).

#CardioSky

#WhyDoIHaveSoMany90YOWithPermanentAF

I agree that burden is endpoint tho

www.jacc.org/doi/10.1016/...

2 months ago 3 1 0 0