Chronopharmacological targeting of mitochondrial dihydroorotate dehydrogenase prevents diet-induced obesity in male mice www.biorxiv.org/content/10.64898/2026.04...

Wearable Dual-Modality Plethysmography for Arterial Modulation and Blood Pressure Dip www.biorxiv.org/content/10.64898/2026.04...

Single-cell atlas reveals age-related cellular shifts underlying fibrosis in murine synovium www.biorxiv.org/content/10.64898/2026.04...

Therapeutic knockdown of MLKL reduces diet-induced obesity and improves insulin signalling in mature adipocytes www.biorxiv.org/content/10.64898/2026.04...

Hemodynamic phenotypes linked to high-altitude subclinical organ damage www.biorxiv.org/content/10.64898/2026.04...

Identification of scavenger receptor BI as a scavenger of free heme that is essential for protection against hemolysis www.biorxiv.org/content/10.64898/2026.04...

Bone microarchitecture and material properties decline differently across midlife for male and female F344 x BN F1 rats www.biorxiv.org/content/10.64898/2026.04...

Lipid mobilization establishes metabolic tolerance and prevents autonomic collapse in infection www.biorxiv.org/content/10.64898/2026.04...

Decreasing peptide deformylase activity is a beneficial strategy for increasing formaldehyde resistance in Methylobacterium extorquens www.biorxiv.org/content/10.64898/2026.04...

Cardiomyocyte caveolae govern myocardial function and sex-dependent regulation of ventricular compliance and resilience via cavin-1 www.biorxiv.org/content/10.64898/2026.04...

Epithelial function of the circadian clock gene, Bmal1, in regulating the mucosa. www.biorxiv.org/content/10.64898/2026.04...

The inner nuclear membrane protein SUN1 regulates cullin-3 neddylation to maintain insulin signaling www.biorxiv.org/content/10.64898/2026.04...

Circadian Regulation of Taste Sensitivity in Human and Rat Active Periods www.biorxiv.org/content/10.64898/2026.04...

Acute exposure to cell-free mitochondrial DNA induces pregnancy-specific aortic endothelial dysfunction and organ-selective inflammation in rats www.biorxiv.org/content/10.64898/2026.04...

Ocular findings in Northern Gannets following an outbreak of high pathogenicity avian influenza (H5N1) www.biorxiv.org/content/10.64898/2026.04...

Revisiting Mouse Cardiac Myocyte Isolation: A Simplified Langendorff-based Method www.biorxiv.org/content/10.64898/2026.04...

Inhibition of p107 alleviates liver steatosis by reducing de novo fatty acid synthesis. www.biorxiv.org/content/10.64898/2026.04...

Use treadmills with caution: Walking Energy Expenditure and Metabolic Cost are elevated compared to overground across multiple speeds in healthy young adults www.biorxiv.org/content/10.64898/2026.04...

Perm1 Gene Therapy Mitigates PRDM16-Associated Cardiomyopathy www.biorxiv.org/content/10.64898/2026.04...

Mineralization kinetics during embryonic avian bone growth: a three-dimensional multiscale and cryogenic imaging approach www.biorxiv.org/content/10.64898/2026.04...

Early-life optimization of mitochondrial aerobic metabolism: high efficiency to grow fast, yet at no oxidative cost www.biorxiv.org/content/10.64898/2026.04...

Expansion Microscopy reveals changes in cellular and extracellular structures between healthy and perturbed tendons www.biorxiv.org/content/10.64898/2026.04...

Muscle Stiffness and Relaxation as Predictors of Explosive Performance: A Structural Equation Model in Competitive Weightlifters www.biorxiv.org/content/10.64898/2026.04...

Optimization and Validation of Whole-Room Indirect Calorimetry for Improved Accuracy and Temporal Resolution www.biorxiv.org/content/10.64898/2026.04...

Selective activation of LH-dependent transcriptional pathways determines ovulatory follicles in the hierarchical ovary of cloudy catshark www.biorxiv.org/content/10.64898/2026.04...

TMEM174 Deficiency Reduces Longevity by Promoting Phosphate-Driven Vascular Calcification www.biorxiv.org/content/10.64898/2026.04...

Structural Insights into the Integration of Temperature and pH by Sperm Calcium Channel CatSper www.biorxiv.org/content/10.64898/2026.04...

Cisplatin exposure alters long-term metabolic phenotype of male, but not female, high-fat diet-fed mice. www.biorxiv.org/content/10.64898/2026.04...

Rapid Remodeling of Human White Adipose Tissue Following Bariatric Surgery www.biorxiv.org/content/10.64898/2026.04...

Effects of hypoxia and low temperature on female physiology and reproduction of Drosophila melanogaster www.biorxiv.org/content/10.64898/2026.04...