H₂-driven CuH catalysis with multifunctional NHCs⚡Guanidine- & iminopyridine NHCs expand reactivity to challenging amides & conjugated substrates🔬Unprecedented substrate scope & a step toward 3d-metal hydrogenations by Teichert et al. @teichertlab.bsky.social
#organocatalysis

👉 buff.ly/3K4tj1A

What a way to kick off the fall term! We had the pleasure of hosting John Molloy from MPI Golm at TU Chemnitz this week. Truly inspiring chemistry revolving around Boron-containing molecules and radicals coming out of his lab.
Found the time for a sunset picture with Kalle as well...

#CHEMnitz
🧪⚗️

This year‘s FuMo took place in the mountains! 🏔️ Together with @ivanafleischer.bsky.social, @teichertlab.bsky.social, @breugstlab.bsky.social & @kretschmerlab.bsky.social we spent four days in Obergurgl, full of interesting scientific talks, inspiring discussions and enjoying the Tyrolian nature.

Great winter term kick-off with an amazing talk by Colin Nuckolls in our @gdch.de lecture series at TU CHEMnitz.

We are looking for a highly motivated PhD student to join our ERC project AGILE at the interface of inorganic, organic and organometallic chemistry. A vibrant Team, cool chemistry and everything takes place in the cultural capitol of Europe CHEMnitz. Apply now: www.tu-chemnitz.de/verwaltung/p...

Site-Selective Copper(I)-Catalyzed Hydrogenation of Amides We present a bifunctional catalyst consisting of a copper(I)/N-heterocyclic carbene and an organocatalytic guanidine moiety that enables, for the first time, a copper(I)-catalyzed reduction of amides ...

For the links to the two original publications, see here:

pubs.acs.org/doi/full/10....

pubs.acs.org/doi/10.1021/...

We have just published a short overview article explaining the concepts copper catalysys with bifunctional ligands published recently. @synlettjournal.bsky.social.

It's a short read, check it out here: www.thieme-connect.com/products/ejo...

#CHEMnitz
#copper
#NHCs

Happy to share the results of a collaboration with the Magerle group (Physics, TU Chemnitz). We have helped out a little bit to show how glycerols and water affect collagen fibrils.

Link to paper: tinyurl.com/3h7emd6x

Press release (German only 😒): tinyurl.com/5yd247pv

#CHEMnitz
#ChemSky 🧪

Happy to see that our paper on bifunctional NHC ligands is published now in EurJOC. Congratulations to all involved and to all readers, feel free to reach out about these ligands if you are interested.

chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...

#catalysis
#CHEMnitz
#ChemSky🧪

Proud to share a true science story. We got inspired by our friends from the Dielmann lab in Innsbruck and joining the pieces together in a new NHC ligand has opened up copper hydride chemistry at low H2 pressure 🎈 for the first time. And new reactivity on top:

bit.ly/4ioPwWe

#CHEMnitz
#ChemSky 🧪

Interested in bifunctional NHC ligands?
We have developed a library approach to some N-heterocyclic carbenes with hydrogen bond donors in the backbone. Check out the preprint here:

chemrxiv.org/engage/chemr...

#CHEMnitz
#ChemSky 🧪
#catalysis

Are you interested in a PhD combining asymmetric transition metal catalysis and data-driven analysis?

We have two PhD positions as part of the EU network CATALOOP (cataloop.eu) that are open to apply:

euraxess.ec.europa.eu/jobs/334833

euraxess.ec.europa.eu/jobs/334837

#ChemSky

Weakly Coordinating Anionic Microporous Polymer Networks as Scaffold for Molecular Gas Phase Hydrogenation Catalysis Anionic microporous polymer networks are prepared from a fluorinated tetraarylborate precursor via the Yamamoto reaction. The charge density can be continuously varied by adjusting the ratio of a neu...

here is a little throwback to the earlier times of the group at TU Berlin (@tuberlin.bsky.social)...

We helped out with some hydrogenation expertise for the group of Arne Thomas and their cool microporous polymer networks:

doi.org/10.1002/cctc...

#chemsky
#CHEMnitz
#hydrogenation

Great to have @evaheviagroup.bsky.social as a Bessel price awardee with us at #CHEMnitz. Thanks for an inspiring talk and a fantastic kick-off of 2025 - the year in which @chemnitz.de is the European Capital of Culture

@teichertlab.bsky.social @breugstlab.bsky.social @mikedelity.bsky.social

Site-Selective Hydrogenation of Amides:
Copper(I) N-heterocyclic carbene catalyst with an organocatalytic guanidine moiety for amide reduction
www.chemistryviews.org/site-selecti...

Site-Selective Copper(I)-Catalyzed Hydrogenation of Amides We present a bifunctional catalyst consisting of a copper(I)/N-heterocyclic carbene and an organocatalytic guanidine moiety that enables, for the first time, a copper(I)-catalyzed reduction of amides ...

A catalyst that can selectively reduce a morpholine-derived amide in presence of a piperidine-derived amide?

Check out our early start into the scientific year here:

pubs.acs.org/doi/10.1021/...

Thanks to @breugstlab.bsky.social for computational support.

#Chemsky 🧪
#CHEMnitz

What I Learned from Analyzing Accurate Mass Data of 3000 Supporting Information Files A Python script for the systematic, high-throughput analysis of accurate mass data was developed and tested on more than 3000 Supporting Information (SI) PDFs from Organic Letters. For each SI file, q...

📊 What I learned from analyzing 3000+ SI PDFs: Only 40% of papers w/ #MassSpectrometry data compliant w/ journal guidelines! From zero #Python experience to an automated checker

Read the paper:
pubs.acs.org/doi/10.1021/...
Try the tool: github.com/match22lab/H...

#DataScience #ChemPython #ChemSky

Thanks for the invitation. What a great two days of science and learnings, including tea highs...

As part of the CATALOOP doctoral network, my group is looking for potential candidates for PhD research in the field of data-driven asymmetric catalysis. Please see here for a list of CATALOOP projects available:

cataloop.eu

Also check out the openings in the groups of the other PIs involved.

The catalysis subgroup has been quite active lately... Here are two preprints in the field of ligand design and bifunctional catalysis with H2:

1. on site-selective amide hydrogenation
bit.ly/3VrZ2z6

2. Cu-catalyzed hydrogenations at 1 bar enabled by a bifunctional NHC ligand.
bit.ly/4ilj2NP

Two smiling, one grumpy...

Very happy about having had Daniel Werz from Freiburg visit us in our GDCh colloquium in Chemnitz yesterday. Fantastic chromophore chemistry 🧪.

#CHEMnitz

It was a great pleasure hosting Johannes Teichert from TU Chemnitz in our GDCh Kolloquium at Kiel University yesterday. We thank you for an entertaining and thought provoking talk and discussion!

Thanks for the invitation and for the pickup from the middle of nowhere when trains 🚂 failed ... 🚕

#CHEMnitz

Indeed, #chemsky ...
Thanks, Matt!

Our review on geometry control and dynamics together with the McGonigal group from York university came out today in Nature Synthesis.

rdcu.be/dH6Np

Thanks to all involved, hopefully this sparks new ideas in hydrocarbon chemistry and beyond.

Zahlen, Daten, Fakten: Das Jahr 2023 in den GDCh‐Regionalstrukturen Click on the article title to read more.

Last year, we hosted a total of 17 events within the @gdch.bsky.social section at TU Chemnitz. This brings #CHEMnitz to the top within all GDCh regional sections. I am also looking forward to the next months with a fantastic line-up of speakers.
onlinelibrary.wiley.com/doi/10.1002/...

TU Chemnitz punktet mehrfach beim CHE-Ranking 2024/2025 Universität überzeugt insbesondere in den aktuell gerankten Fachgebieten Chemie, Informatik, Mathematik, Physik und Sportwissenschaft

Die Technische Universität Chemnitz punktet mehrfach in den Fächern Chemie und Physik. Come study #Chemistry in #CHEMnitz #Chemsky

www.tu-chemnitz.de/tu/presseste...

Yesterday we had @johanneswalker.bsky.social from Göttingen as a speaker in #CHEMnitz. Great work on strained hydrocarbons - in a competitive field! Looking forward to the new results coming up from the group!

The obligatory picture with Karl and @breugstlab.bsky.social below

ChemSky 🧪

Thinking back to the #StöckhardtLecture a couple of weeks back. I think it is great not only for students but also for the researchers to have an truely inspiring talk. This one by Ben Feringa really stood out and it certainly filled up our "science enthusiasm battery".

#CHEMnitz #chemsky 🧪