Link to the paper:
www.frontiersin.org/journals/mol...

The mechanism of ribosomal recruitment during translation initiation on the Type 2 encephalomyocarditis virus IRES - The EMBO Journal The encephalomyocarditis virus (EMCV) internal ribosomal entry side (IRES) and other Type 2 IRESs favor translation of the viral genome during infection. The domains H-L of these IRESs specifically in...

Cryo-EM studies of 48S initiation complexes formed on the EMCV IRES reveal specific contacts that are functionally required for 5’end independent translation initiation
Tatyana Pestova, Christopher Hellen, @joachim123.bsky.social and colleagues
link.springer.com/article/10.1...

Insane how much we don't even know we don't know!

β-arrestin directly activates Src through two interaction interfaces, revealing how it can function as active signaling hub, not just GPCR desensitizers.

Great collaboration between the Lefkowitz lab at Duke and des Georges lab @nyupainresearch.bsky.social
nature.com/articles/s41...