Opinion | We Are Watching a Scientific Superpower Destroy Itself

We Are Watching a Scientific Superpower Destroy Itself @nytimes.com

www.nytimes.com/2025/09/08/o...

Structure of CFTR bound to (R)-BPO-27 unveils a pore-blockage mechanism @nature.com

www.nature.com/articles/s41...

Senate committee endorses NIH budget increase, rebuking Trump administration’s proposed 40% cut Senators from both parties endorsed a $400 million increase to the budget of the National Institutes of Health on Thursday

Senate committee endorses NIH budget increase, rebuking Trump administration’s proposed 40% cut @statnews.com

Dr. Amish Raval named to Endowed Professorship in Cardiovascular Medicine Amish Raval, MD, professor, Cardiovascular Medicine, has been named to a new Endowed Professorship in Cardiovascular Medicine thanks to a significant gift from a grateful patient family. The endowment...

Great clinician, scientist, and even better person! www.medicine.wisc.edu/news/0725202...

Welcome sign

Phenomenal learning at the week long ACP board review course in Philadelphia!

Physiological pacing: mechanisms, clinical indications, and perspectives Abstract. Normal cardiac function depends on a highly efficient cardiac conduction system. Conduction system disease impairs cardiac function, which can re

Physiological pacing: mechanisms, clinical indications, and perspectives🔓
academic.oup.com/eurheartj/ad...

Former student and PhD advisor having happy dinner

Great to catch up with PhD advisor in Philly

Once a mentor always a mentor 👍

Check out #PanEcho, now in @jama.com

✅ open weights
✅ multiview multitask reporting
✅ international validation
✅ works with POCUS

Amazing effort @cardslab.bsky.social
@giholste.bsky.social @rohankhera.bsky.social

+ @atlaswang.bsky.social, Márton Tokodi & Attila Kovács

#CardioSky #EchoSky

Real Doctors of New York Spill Their Guts

"A terrifying imbalance lies at the heart of every doctor-patient relationship: The doctor can ask practically anything about the patient... The patient knows almost nothing about the person in the white coat...” @nytimes.com www.nytimes.com/2025/06/24/w...

Mechano-energetic uncoupling in heart failure Nature Reviews Cardiology, Published online: 22 June 2025; doi:10.1038/s41569-025-01167-6In this Review, the authors focus on the tight interaction between cardiac mechanics and mitochondrial energetics, discuss how this mechano-energetic coupling is disturbed in various acquired and inherited forms of heart failure, and summarize the established and emerging treatments for heart failure that target this mechano-energetic uncoupling.

New online! Mechano-energetic uncoupling in heart failure #CardioSky

Upcoming Payments from student loan company shows $0 due for May - July, but $1766.14 due starting in August 2025.

What. The. Fuq. 😩

My previous #studentloan payment was ~$250. Even though no payment is currently required, I have faithfully made that same payment each month.

But now #Trump has killed my #science 🧪 job options through #NIH cuts and on top he wants a rent note.

How are other trainees coping rn?

I'm a current Harvard graduate student and I found out today that I had my NSF GRFP terminated without notification. I was awarded this individual research fellowship before even choosing Harvard as my graduate school

Renewal of NIH grants linked to more innovative results, study finds Nature - Survey of hundreds of scientists’ work suggests that cutting off funding disrupts focus and reduces the novelty of research.

Innovation takes time

US scientists who received renewals from the NIH over the past four decades produced more novel research than those who didn’t
https://go.nature.com/44s6cc5

Budget released today:
40% cut to NIH
50% cut to NSF
If enacted, this will destroy academic research in the United States. It will also have a major trickle down effect on the entire academic ecosystem

To maintain our operational integrity and continue delivering the service and quality our customers rely on, we have made the decision to implement a tariff surcharge. This temporary surcharge is in lieu of a tariff cost passthrough and protects our customers from experiencing the full impact of the broad tariff rates, some of which are very high. By leveraging a surcharge, we retain flexibility to adjust or remove the surcharge if the situation changes in the coming weeks or months. Effective May 5, the surcharge will be applied to product orders shipped to locations in the United States which reflects the tariffs' broader impacts on our overall global supply chain processes, including production and procurement costs in addition to any direct costs on products. This charge will appear as a separate line item on quotes and invoices.

Welp, it begins. Sigma Aldrich.

Exclusive: NSF stops awarding new grants and funding existing ones US science funder also plans to screen grant applications for compliance with ‘agency priorities’.

Staff members at the US National Science Foundation (NSF) were told on 30 April to “stop awarding all funding actions until further notice,” according to an email seen by Nature.

https://go.nature.com/44Ugf9V

I'm in! Poster part two

Amazing time at the m AAP/ASCI/APSA meeting with great science and friends!

🚨The application deadline for the 2025 SGP Excelsior Award is 1 June 2025. Learn more and apply at sgpweb.org/awards/excel...

"American science is the envy of the world, but this global leadership is now threatened by draconian cuts to federal support of biomedical research through the defunding of grants and drastic reductions in funding for essential research costs and infrastructure."

Management of Heart Failure With Improved Ejection Fraction: Current Evidence and Controversies

Contemporary management of HF with improved EF, specifically thoughts on who and when to peel back medical therapies. www.jacc.org/doi/10.1016/... @jaccjournals.bsky.social #cardiosky

I put the ‘R’ in the MMR vaccine, and I’m scared that, like measles, rubella could make a comeback under RFK Jr. |Opinion Robert F. Kennedy Jr.’s efforts to make the use of the MMR vaccine voluntary are not only letting loose measles but also will allow mumps and rubella to return to America.

"Those who do not accept vaccination remain susceptible to the infections against which the vaccines were developed, and they serve as vectors for the spread of the infections to unvaccinated individuals"

www.inquirer.com/opinion/comm...

Opinion | America’s Brightest Minds Will Walk Away Young researchers are choosing between staying in science and staying in the United States.

America’s Brightest Minds Will Walk Away

www.nytimes.com/2025/04/03/o... ⁦

Conduction system pacing: promoting the physiology to prevent HF

Background and Clinical perspectives of HBP and LBBP area in HF
link.springer.com/article/10.1...

#HF #CardioSky #CardioEd @cardioobdoc.bsky.social @drrajivsankar.bsky.social @annakatebarton.bsky.social @vietheartpa.bsky.social

Top scientists warn that Trump policies are causing a 'climate of fear' in research Some 2,000 scientists, including dozens of Nobel Prize winners, have signed an open letter warning that the U.S. lead in science is being "decimated" by the Trump administration's cuts to research.

Some 2,000 scientists, including dozens of Nobel Prize winners, have signed an open letter warning that the U.S. lead in science is being "decimated" by the Trump administration's cuts to research.

‘One of the darkest days’: NIH purges agency leadership amid mass layoffs In shock move, four institute directors at the US biomedical agency are removed from their posts.

‘One of the darkest days’: NIH purges agency leadership amid mass layoffs @nature.com

www.nature.com/articles/d41...

Great @sgpweb.bsky.social EPIC seminar on BK channel auxiliary subunits!

So much mechanism could be uncovered by this investigation

At today's Congressional Forum, Dr. Larry Saltzman testified that NIH-funded research was crucial to his 15-year survival with chronic lymphocytic leukemia. "For patients waiting on the next treatment, time is everything. These cuts could rob us of the time we need most."

Here's our newest study: we reveal the molecular principles of neuronal excitation by glutamate, and how physiological temperatures influence this process.

www.nature.com/articles/s41...
www.nature.com/articles/d41...

Led by @anish-mondal07.bsky.social, published in @natureportfolio.nature.com

Now and competitive renewals

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