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Posts by Alvin Xu

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The fiscal impact of biodiversity loss and a pathway for conservation finance Profit-seeking investors could align their muncipal bond investments with conservation actions

How do we close the $700B annual biodiversity funding gap? A new study points to municipal bond markets for solutions.

#ConservationFinance #Biodiversity #ScienceSky #ESG #Science #SciComm

4 weeks ago 0 0 0 0
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New HIV cure approach forces hidden virus into tripping immune sensor Strategy gains momentum after promising results in cell studies and infected people

New HIV cure approach forces hidden virus into tripping immune sensor. Even with antiretroviral drugs, latently infected cells may lead to chronic inflammation, quietly raising the risk of heart disease, cancer, and organ failure. Treatments that reduce reservoirs can change these outcomes.

#SciSky

4 weeks ago 5 1 2 0
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Earth’s first major extinction was worse than we thought Fossil finds suggest nearly 80% of life on Earth died some 550 million years ago

New research finds that Earth’s first major extinction was worse than we thought

4 weeks ago 0 0 0 0
GitHub - dickoa/samplyr: A Tidy Grammar for Survey Sampling A Tidy Grammar for Survey Sampling. Contribute to dickoa/samplyr development by creating an account on GitHub.

I love R for everything statistics, but I've always been a little jealous of statisticians using SPSS Complex Samples or SAS SURVEYSELECT to design their samples.

So I decided to build samplyr, a tidy and pipe-friendly grammar for survey sampling design in #rstats.

dickoa.gitlab.io/samplyr/inde...

1 month ago 110 23 5 3

"You’re at a conference. The lights are low, it’s the last speaker of the day, engagement has hit rock bottom. Phones come out...Re-imagine this setting, the lights are low, it’s the last act of the day, the band walks onto the stage, engagement goes through the roof. No one wants it to end."

2 months ago 0 0 0 0
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Arc AIxBio Fellows Program for Undergrads | Arc Institute Arc Institute is a independent nonprofit research organization headquartered in Palo Alto, California.

@arcinstitute.org just announced an AI & Bio fellowship for undergrads!

I'm building a team of 2–3 to apply. My interests are in AI for oncology or genomics. Looking for teammates with deep learning/modeling experience.

If you are interested, send me a DM or reply below.

#SciSky #AIxBio #CompBio

2 months ago 0 1 0 0
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We’re working on a story about how children’s immune systems and microbiomes develop and we want to hear from you. Have you let your kids eat food that was dropped on the ground? 🍭 Argued with grandparents about cleanliness? 🧼 Saw your child do something incredibly gross? 🤢 Call us at 877 4 SCIFRI.

2 months ago 48 12 7 0
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Brain-to-voice neuroprosthesis restores naturalistic speech Marking a breakthrough, an AI-based model streams intelligible speech from the brain in real-time.

Imagine a computer that can translate thought to speech in under 1 second.

Groundbreaking work from UC Berkeley & UCSF uses AI to restore naturalistic, real-time voice for those with severe paralysis, bypassing previous latency hurdles.

#SciSky #MedSky #BCI #Neuroscience #NeuroTech #AI #MedTech

2 months ago 5 3 0 0
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Research posts on Bluesky are more original — and get better engagement Bluesky posts about science garner more likes and reposts than similar ones on X.

Research posts on Bluesky are more original — and get better engagement www.nature.com/articles/d41...

#SciSky #AcademicSky #OpenScience #SciComm #SocialMediaAnalysis

2 months ago 46 17 0 1
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A targeted combination therapy achieves effective pancreatic cancer regression and prevents tumor resistance | PNAS Pancreatic ductal adenocarcinoma (PDAC) has one of the lowest cancer survival rates. Recent studies using RAS inhibitors have opened the door to mo...

Pancreatic cancer is the third deadliest cancer. Treatment often fail due to resistance.

A new study in PNAS led by Mariano Barbacid tackles this with a triple combination therapy that induces robust tumor regression and prevents the onset of tumor resistance in mice.

#SciSky #MedSky #Oncology

2 months ago 8 5 0 0
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A fossilized trilobite. This specimen, from the Burgess Shale, preserves "soft parts"—the antennae and legs. Dimly lit on one side, with bright light shining on the other side providing detail and contrast.

A fossilized trilobite. This specimen, from the Burgess Shale, preserves "soft parts"—the antennae and legs. Dimly lit on one side, with bright light shining on the other side providing detail and contrast.

Why did life explode in complexity 538.8 million years ago?

Inspired by a friend's question, I wrote my first Substack deep-dive on the factors that ignited the Cambrian explosion.

Read here: open.substack.com/pub/biobrief...

#ScienceSky #Biology #Evolution #SciComm

2 months ago 0 1 1 0

What’s particularly exciting is the potential to combine mechanistic models with AI, especially for problems with limited data. Physics-informed neural networks (PINNs) let neural nets leverage physical laws, accelerating learning and improving predictive accuracy.

2 months ago 2 0 0 0
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Using mathematical modelling and AI to improve delivery and efficacy of therapies in cancer - Nature Reviews Cancer Here Harkos et al. review the role of continuous models and discrete models in predicting and understanding therapy delivery and efficacy in solid tumours. They propose ways to integrate mechanistic a...

Mathematical oncology aims to model cancer to improve the delivery and efficacy of therapies. Broadly, models fall into two classes: mechanistic and AI-driven. Mechanistic models can be further divided into continuous and discrete/stochastic approaches.

www.nature.com/articles/s41...

2 months ago 1 0 1 0