Grateful to all my co-authors and collaborators for their invaluable contributions—and a special thank you to Yu Alex Kato, William Heath, and Irina Caminschi for the collaboration on this project!

Our findings provide new insights into how B cells discriminate between antigens—highlighting mechanisms that help prevent autoreactive responses.

In this study, we used a panel of monoclonal antibodies to investigate how naïve B cells can selectively respond to membrane-bound antigens while largely ignoring their soluble counterparts.

MHC II–restricted presentation of soluble antigen by naïve B cells is impaired upon engagement with membrane-associated antigen: A potential mechanism to mitigate autoreactivity Abstract. T cell tolerance to self can prevent self-reactive B cells from mounting effective autoimmune responses by limiting their available help. However

Excited to share our latest publication in the
@jimmunol.bsky.social! 👇🧵

@thedohertyinst.bsky.social

academic.oup.com/jimmunol/art...

Thrilled to see this published! This represents a major milestone for the treatment of first-line DLBCL patients, clearly demonstrating the safety and efficacy of bispecifics. Congratulations to Adrian Minson, Michael Dickinson, and the team.

ascopubs.org/doi/full/10....

@petermaccc.bsky.social

I am honoured to have been awarded a Medicine/Science grant from The CASS Foundation! This support will enable us to continue our research in harnessing CD4 T cells to improve outcomes of B-cell lymphoma patients treated with bispecific antibodies known as T-cell engagers.
@petermaccc.bsky.social

Thrilled to share that our review paper is on the cover of Trends in Cancer! Excited for the conversations this will spark in the field.
👉 t.ly/L0BS0

Beautiful art designed by Lewis Au Illustration by Jessica Johnstone.