Landing page for scienceimpacts.org
Today, our #SCIMaP team released an impact analysis of the White House proposed FY 2027 NIH and NSF budgets.
Bottom-line: if enacted, cuts to science and medical research would lead to $35B in economic losses and 150,000 lost jobs in communities all across the US.
scienceimpacts.org
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An mRNA treatment for PANCREATIC CANCER was in trials, among many other uses. Choosing to end this research is choosing to sentence millions to an early, painful death
If you’ve been moved & inspired by Artemis, NASA needs your help. Literally during A2, the president proposed cutting NASA science 47%, canceling 54 missions, including many already in-flight. To help stop these cuts, check out @planetarysociety.bsky.social www.planetary.org/save-nasa-sc...
tl;dr: NIH is running at about 60% of pre-Trump levels and NSF is running at about 20% of pre-Trump levels of funding-outlays (some directorates far below even that). Utterly catastrophic. An unforced disaster for U.S. society, and the world
It is past time to do a power mapping of which consultants are advising which universities, and which Super Efficiency Optimizing Plans they're laying out as their Burger King menu of options
The authors of the two papers. Carlos O. Miller standing on the left, looking down upon a couple of glass beakers. Opposite him, from the back to the front, are Malcolm H. van Saltza, Francis Shigeo Okumura, Folke K. Skoog and Frank M. Strong. Below the photo are the headers of their two papers describing kinetin, the first cytokinin: “Kinetin, a cell division factor from desoxyribonucleic acid” by Carlos O. Miller, Folke K. Skoog, Malcolm H. van Saltza and Frank M. Strong, and “Structure and synthesis of kinetin” by Carlos O. Miller, Folke K. Skoog, Francis Shigeo Okumura, Malcolm H. van Saltza and Frank M. Strong. Both published in 1955 in the Journal of the American Chemical Society.
#PlantScienceClassics #20: Kinetin & Cytokinins. In 1955 Carlos Miller, Folke Skoog & co-workers describe the first #Cytokinin and its role in promoting cell division and growth promotion. #Phytohormones #PlantScience #PlantDevelopment
pubs.acs.org/doi/abs/10.1...
pubs.acs.org/doi/abs/10.1...
Taxpayers pay twice:
Trump is giving one billion taxpayer dollars to a company so it WON'T build clean offshore wind.
Fewer clean energy projects pushes up utility rates, which costs families even more.
I just had that conversation earlier this week. The college dean is deciding if they will (dis)continue the bioinformatics training program for grad students. An argument for discontinuation is that students will use GenAI to help them code, so they don’t need to learn bioinformatics.
A line graph showing the success rates for fiscal years 2015-2025 as a function of percentile score. The curve for fiscal year 2025 is substantially lower than for previous fiscal years.
With these results in hand, we can now reproduce the graph that @joshuasweitz.bsky.social posted.
It is still shocking, but we can now understand why it looks the way it does: The number of R01 and R56 awards were down while the number of applications were up.
16/20
Highly recommend this pod on AI where @chrislhayes.bsky.social interviews Gideon Lewis-Kraus, author of a big recent New Yorker piece on the subject. Tons of interestng discussion, especially for us ex-philosophy geeks.
Forthwith, a short 🧵
We are very excited to share a new resource from our team: spatial subcellular proteome maps in plants! We developed an MS-based method that registers localizations of about 8000 proteins in Arabidopsis roots in a single experiment.
(1/9)
www.biorxiv.org/cgi/content/...
And the new NCI Director moves to piss away his scientific credibility.
First, killing cancer cells is a very low bar; many compounds kill cancer cells and are not the least bit useful for treating cancer.
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Even after Trump is gone, the world will remember that he threatened to forcibly seize the territory of a peaceful democratic ally, and our institutions failed to immediately remove him. That makes US dangerously unreliable, not just one senile gangster.
I wrote about the cosmic grandeur of American space science and this president’s foolish attempts to sabotage it
www.theatlantic.com/magazine/202...
OK, crash course in oil. Oil has two main gradings, viscosity (light or heavy) and sulfur (sweet or sour). A light (low viscosity) and sweet (low sulfur) oil is easier to process into gasoline and other products than a heavy and sour one, so the light & sweet oil commands a premium price.
Microscopy Bat signal!
I want to compile a list of biological samples that demonstrate microscope capabilities, including the reagents to generate them. Please send me anything you know of!! Beads are great for QC, but there's a different teaching benefit with biology. 1/n
The Nobel Prize committee should announce the World Cup winner tomorrow
While this is so deeply beautiful and moving about the important place of art in society and I'm so glad Dr. Baum shared this with us, I'm sad Stoppard never knew.
Please tell people how much their work impacts you. Write to a playwright, academic, artist, etc and let them know how they moved you.
The late Miocene possibly had lower athmospheric pCO2 than we have right now (but higher than pre-industrial), but that was enough for there not to be permafrost in North Greenland.
Once a local threshold is reached, that is enough sometimes. 🧪
Link: www.nature.com/articles/s41...
I don’t know if anyone else notices or cares, but when I see a presentation in which the speaker uses obviously generated-AI images to illustrate their slides, it makes me immediately less confident in whatever other content they’re presenting.
green and yellow cover of University Keywords, ed by Andy Hines
Table of contents for University Keywords University: An Introduction, Andy Hines Academic Freedom, Jennifer Ruth and Ellen Schrecker Adjunct, Heather Steffen Admissions, Scott Gelber Alternative Institutions, Andy Hines and Eli Meyerhoff Athletics, Wayne L. Black Board of Trustees, Asheesh Siddique Kapur Budget, Juan Pablo Pardo-Guerra Campus, Davarian Baldwin Classroom, Richard Simpson Critical University Studies, Rana M. Jaleel, Isaac Kamola, and Heather Steffen Debt, Eleni Schirmer and Jason Wozniak Degree, Christopher Newfield Discipline, Vineeta Singh Diversity, p.s. kehal EdTech, Annie McClanahan and Louise McCune Endowment, Dennis M. Hogan Entrepreneurship, Jesse Goldstein
Table of contents for university keywords Fiction, Jeffrey J. Williams Legislation, Elizabeth Tandy Shermer Noncitizen Student, Abigail Boggs Police, Yalile Suriel and Grace Watkins Ranking, Jelena Brankovic and Stefan Wilbers Revenue, Dan Nemser and Brian Whitener Risk Management, Mattie Armstrong-Price Sustainability, Kai Bosworth, Jesse Goldstein, Andy Hines, and Eli Meyerhoff Title IX, Rana M. Jaleel Union, Zach Schwartz-Weinstein Appendix: Questions to Consider for Composing a Keywords Entry Contributor Bios Acknowledgments Index
It's publication day for UNIVERSITY KEYWORDS. Across 27 sharp essays, the book offers a critical account of the political economy of US higher education, how it came to be structured this way, and how together we might build a better university together.
When does sloppiness become misconduct?
What level of manipulation becomes fabrication?
If authors say it is an error, should we trust them?
If raw data is missing, is there any justification for proceeding?
Should you report to the institution?
#AIMOS2025
Q: Why is international collaboration essential for advancing research?
A: Understand global initiatives
No: It promotes shared standards
#AIMOS2025
Hackathon Speaker/Chair = Ginny Barbour Janet Catterall Topic/Title = Hacking the system: improving research assessment by stealth Outline = The aims of this session are to: 1. Ensure participants are familiar with key principles of responsible research assessment 2. Understand the link between responsible research assessment, open science and research quality 3. Take away 2-3 concrete actions that participants can use to ""hack"" research assessment at their institution Many researchers are keen to see improvements in research assessment in order for it to support open and reproducible research. However, it is often the case that researchers don‚Äôt know where to start with change at their institution, and may feel relatively powerless in doing so. Using the new guide from DORA - A Practical Guide to Implementing Responsible Research Assessment at Research Performing Organizations (https://sfdora.org/resource/practical-guide/) we will outline key starting points and tools for effecting change. Through group discussions, we will collaboratively develop a set of simple ways that individuals - especially early and mid-career researchers (who are often poorly represented in policy discussions) - can take back to their institutions, and via their own local networks and peer groups help initiate and catalyse responsible research assessment ‚ especially as it relates to open science and research quality.
Slide about DORA
Now attending the Hackaton "Hacking the system: improving research assessment by stealth"
DORA: Valuing academics by a wider range of scholarly products (wider than number of publications/citations), such as sharing datasets, protocols, software.
sfdora.org
#AIMOS2025
Speaker and title slide
1. Madeleen van der Merwe: Statistical Errors in Health Journal Articles. A systematic review.
We looked at 53 articles - identified 940 statistical errors
#AIMOS2025
Cuts to NIH grants have disrupted at least 383 clinical trials, with infectious disease research hit especially hard. A stark example of the real-world repercussions of Trump and co.'s health policy 🧪 my latest:
Important new analysis identifying the scope of clinical trials disrupted because of NIH shenanigans.
> 74 thousand trial participants affected
jamanetwork.com/journals/jam...
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how the cave generator i'm working on works!
this uses patches (see rainbows, beginning of each run) with distinct cellular automata assigned to them.
patches which are along edges are given a chance of becoming a wall, which chews up edges and makes it less rectangular.
then it will connect up
weird js bug. does anyone know how an undefined is creeping into this iteration over an array with no undefined in it? chrome, windows if it's implementation specific.
i have tested a number of times and it seems not to happen in windows firefox.
