This cool study on compounds that can kill Plasmodium inside mosquitoes and can be applied to bed-nets was contributed to by the Riscoe lab at MMI!

Congratulations to the Tafesse lab on their recent publication on the effects on timing in repeat vaccinations!

Analysis of Factors That Regulate HIV-1 Fusion in Reverse Based on observations that HIV-1 envelope (Env) proteins on the surfaces of cells have the capacity to fuse with neighboring cells or enveloped viruses that express CD4 receptors and CXCR4 co-receptor...

Congratulations to the groups of Eric Barklis and @tafesselab.bsky.social for reporting an analysis of factors that regulate HIV-1 fusion in reverse pmc.ncbi.nlm.nih.gov/articles/PMC...

Vaccine experts band together to counter U.S. government misinformation Vaccine Integrity Project intends to provide scientific responses to ill-founded vaccine moves

Vaccine scientists and medical leaders have announced they are launching an unprecedented initiative to react to vaccine misinformation and scientifically unfounded vaccine decisions by the U.S. government. scim.ag/3ES9r1Q

Every 10 seconds vaccination saves a life. Immunization for all is humanly possible.

Vaccines have saved 154 million lives in the past 50 years. A reminder of what is #HumanlyPossible. Science saves lives.
#VaccinesWork

bit.ly/wiw2025

Some important additional considerations about the need to comment of the implementation of schedule F.

First, several sources have indicated that Institute Director and Division Director positions would likely be converted but not Program Officers.

1/n

NIH cancels its first and largest study centered on women The Women’s Health Initiative has produced numerous influential findings

I don't get how anyone can possibly be okay with ending the WHI. This study has accrued decades of data from 42000 women and it is still going. It helps to address critical research gaps that have been allowed to go unfilled because of durable misogyny and provides invaluable insight into aging.

Science, not silence! @rauchlab.bsky.social

‘We’re hurting.’ Trans scientists call for recognition and support from research community “Rigorous science demands” it, authors write in landmark commentary

In a landmark commentary last year, 24 scientists from around the globe—all of whom either identify as trans or have trans family members—called for recognition and support from the research community. #TransDayOfVisibility scim.ag/4l8LK5O

Celebrating Women in Immunology YouTube video by The American Association of Immunologists (AAI)

AAI is dedicated to fostering a supportive and inclusive environment where women can thrive. We are committed to providing resources, mentorship, and opportunities to empower the next generation of women immunologists. Learn more at aai.org.

#WomensHistoryMonth

Cuts to science research funding cut American lives short − federal support is essential for medical breakthroughs The National Institutes of Health has been integral to scientific progress in treating countless human diseases. Without its support, patients will ultimately pay the price.

Federal funding of biomedical research has been a remarkably successful partnership, with benefits that are so intertwined in our daily lives that they can be easy to take for granted.

So what will we lose if the U.S. continues to defund research?

theconversation.com/cuts-to-scie...

🚨I converted the list of terminated #NIH grants (as of 3/22) into a google sheet. I added activity codes and award jurisdictions (see tabs for grant count and $ by each). Note this HHS list likely does not include all planned/completed terminations as of this date.🚨 Please use, share and distribute!

Pacific Northwest's ‘forest gardens’ were deliberately planted by Indigenous people Finding suggests humans have added value to forests in lasting ways

Some scientists had argued that the “forest gardens” of the Pacific Northwest were accidental byproducts of fire, flood, or land clearing.

But a 2021 study showed the contrary: Indigenous peoples deliberately cultivated them. scim.ag/41Gocwe #InternationalDayOfForests

Ubiquitin is directly linked via an ester to protein-conjugated mono-ADP-ribose | The EMBO Journal imageimageCertain E3 ligases have been found to ubiquitylate hydroxyl groups on free NAD+ and ADP-ribose in vitro, but the in vivo occurrence of this dual post-translational modification has remained ...

New research from the @jnpruneda.bsky.social and @michaelnadbio.bsky.social labs:
In this collaborative work, the groups show that ubiquitin is directly linked to mono-ADP-ribose modifications on proteins, a process called “MARUbylation".

www.embopress.org/doi/full/10....

New publication out of the @rauchlab.bsky.social at OHSU MMI

Science Amid Chaos: What Worked During the Pandemic? What Failed? (Gift Article) As the coronavirus spread, researchers worldwide scrambled to find ways to keep people safe. Some efforts were misguided. Others saved millions of lives.

Of the most significant public health measures introduced during Covid, which have held up scientifically, and which turned out to be wrongheaded?

www.nytimes.com/2025/03/14/h...

As federal funding for research is uncertain, we need to diversify funding sources for our PhD students.

Here is a comprehensive list of >160 PhD fellowships and funding opportunities, mostly from private foundations and scientific societies.

Download it here: research.jhu.edu/rdt/funding-...

Powerful Speeches From Trans Dems Flip 29 Republicans, Anti-Trans Bills Die In Montana Transgender Reps Zooey Zephyr and SJ Howell delivered powerful speeches on the Montana House floor on Thursday. Republicans defected en masse to join them in voting against anti-trans bills.

For a more full breakdown, check out @erininthemorning.com’s newsletter post: www.erininthemorning.com/p/powerful-s...

@standupforscience.bsky.social great turnout in Oregon for #standupforscience2025 !!! Thanks to all the amazing speakers!!!

Oregonians standing up for Science!

Science is a public good! Join us in Salem, OR right now! #standupforscience

Supreme Court Rejects Trump’s Bid to Freeze Foreign Aid The move came after Chief Justice Roberts temporarily paused a trial judge’s order requiring the administration to release more than $1.5 billion.

The Supreme Court rejected President Trump’s emergency request to freeze nearly $2 billion in foreign aid

"The ruling represented one of the court’s first moves in response to the flurry of litigation filed" because of Trump/Musk's govt cuts.
www.nytimes.com/2025/03/05/u...

New NIH grant terminations target transgender studies—even in mice Science has identified more than two dozen halted grants amid Trump’s transgender crackdown, right as NIH suspends its own researchers who worked on topic

Science has identified more than two dozen halted grants amid Trump’s transgender crackdown, right as NIH suspends its own researchers who worked on topic. scim.ag/43ppHl2

a cartoon of homer simpson holding a card ALT: a cartoon of homer simpson holding a card

Bluetorial:

The announcement to move scientific review out of the institutes and centers into the Center for Scientific Review (CSR) and its potential consequences

STAND UP FOR SCIENCE March 7, 2025. Washington DC and nationwide. Because science is for everyone.

Join me on Friday to Stand Up for Science! Standupforscience2025.org

Quote stating "Racial affinity groups ... strengthen the STEM community." attributed to Chaudhary et al.

"To protect scientists and scientific output, US stakeholders must work to protect [racial] affinity groups from government interference," write the authors of a new #LetterToScience. scim.ag/4ki1MtL

Opinion: Scientists on how NIH cuts will hurt all Oregonians. - Portland Business Journal "These cuts will cripple biomedical research and drug development in the U.S. We should be investing more in science, not less."

@laurenrodda.bsky.social, @nicelab.bsky.social , @jnpruneda.bsky.social and I wrote an OpEd on the impacts of NIH cuts on Oregon: www.bizjournals.com/portland/new...

It was signed by over 450 OHSU researchers!

It’s unfortunately paywalled, DM me if you’d like a gift link or a pdf of it.

Map of Stand Up for Science events, with official SUFS events in Red and solidarity events in Blue

WHERE WILL YOU BE ON MARCH 7TH!?

Head to www.standupforscience2025.org/local-event-information/ or the link in our bio to find your closest event—or add one if you're hosting one!

#standupforscience2025

The horror show moves to the next level…

Grant termination based on studying transgender issues!

Week 6 Figuring out what to focus on now & what to focus on next in science and higher ed

The World Health Organization calculates that measles vaccinations saved 60 million lives, 2000-2023. On Thursday, CDC scientists were forbidden to co-author papers with WHO colleagues.

Other attacks on science + what to do about them in this week's debrief buttondown.com/liminalcreat...
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