🎉 Congrats to Dr. Laura Luebbert ( @lauraluebbert.com ) for receiving the 2025 FutureHouse Fellowship! She’ll develop AI tools to detect viral sequences in genomic data & analyze virome data from 4,000+ people. Creator of gget & champion of open science—go Laura! 🧬🙌

100&Change A competition for a $100 million grant to fund a single proposal that promises real and measurable progress in solving a critical problem of our time.

We’re so excited to announce that we're a #100andChange Finalist! We’re one of five teams in the running for a $100 million grant to help solve one of the world's most critical social challenges!
Learn more here: www.100andchange.org
#100andChange #LeverforChange #SocialImpact

Earlier this year, Sabeti Lab members traveled to 🇳🇬 to work with our incredible partners at ACEGID/IGH on LAMP diagnostics & Lassa virus sequencing. We're so grateful for this ongoing collaboration 🌍🤝 For more moments from the trip, check out our Instagram!

Geospatial and demographic patterns of SARS-CoV-2 spread in Massachusetts from over 130,000 genomes Despite intensive study, gaps remain in our understanding of SARS-CoV-2 transmission patterns during the COVID-19 pandemic, in part due to limited contextual metadata accompanying most large genomic s...

I’m thrilled to share our latest preprint! We analyzed >130,000 SARS-CoV-2 genomes from MA to investigate complex transmission dynamics—from statewide patterns, within specific facilities, and at the individual level 🦠🧬

Check out the preprint here ⬇️
www.medrxiv.org/content/10.1...

2025 Fellows Will Break New Ground Through Interdisciplinary Research • Schmidt Science Fellows Thirty-two early career researchers, tackling issues from improving food security to developing better medical implants, have been announced as the 2025 Schmidt Science Fellows and will pursue innovat...

Big congratulations to Dr. Jon Arizti Sanz for being named a 2025 Schmidt Science Fellow! 🎉 The fellowship empowers early career scientists to pivot into new fields, lead interdisciplinary research, and tackle global challenges. We’re so proud of him! 💥🌍 read more -> bit.ly/4ciXAGk

What a month of papers! Check out the newest one on H5N1 monitoring in the thread below 🧵👇

Want a primer on the @sabetilab.bsky.social latest publication? See the thread I wrote on the preprint 👇

Delphy: scalable, near-real-time Bayesian phylogenetics for outbreaks Pathogen genomic analysis is central to tracking, understanding, and containing outbreaks, but complexity and high costs of state-of-the-art (SOTA) phylogenetic tools limit global access and impact. W...

We’re excited to share the completed preprint of Delphy — our new tool for scalable, near-real-time #Bayesianphylogenetics for outbreaks! 🚀
Check it out here: www.biorxiv.org/content/10.1...
Explore Delphy: delphy.fathom.info
Led by #PatrickVarilly @sabetilab.bsky.social @fathom.info 🧵1/17

And our #authorselfie

Thrilled to share our latest work—Lyra shows how principled AI design can democratize biological sequence modeling, bringing it to scientists everywhere.
@krithik-bs.bsky.social @sameedms.bsky.social‬ #AlbertGu
#MichaelMitzenmacher
@sabetilab.bsky.social @broadinstitute.org @harvard.edu

JUNIPER: Reconstructing Transmission Events from Next-Generation Sequencing Data at Scale Transmission reconstruction--the inference of who infects whom in disease outbreaks--offers critical insights into how pathogens spread and provides opportunities for targeted control measures. We dev...

We present JUNIPER, our outbreak reconstruction tool that incorporates within-host variants, models missing data, and scales to large, sparsely sampled datasets to achieve state-of-the-art performance. Led by @ivan_specht et al. @sabeti_lab. www.medrxiv.org/content/10.1... 1/12 🧵

Closing out Black History Month with a celebration a few members of our incredible team! 🎉✨ We’re grateful for them today and every day. Check out Pardis’s thread below to learn more about their impact!🥳 ⬇️ #BlackHistoryMonth

Wrapping up Black History Month with a shoutout to the incredible Tomi Siyanbade! 🎉✨ Check out @pardissabeti.bsky.social thread below to see her amazing accomplishments. We're so grateful for all the time and impact she’s had in our lab! 💙

🐦‍⬛🔬Bird Flu (H5N1) – what’s the deal? 🤔
@pardissabeti.bsky.social joined @scishow.bsky.social
to break it all down—its origins, where it stands today, and why it matters. 🦠🐦 Here’s a sneak peek! 👀 Want the full story? Head to the SciShow's YouTube channel: youtu.be/5CyVi4UzKxE?... 🎥✨

Gratitude never goes out of style! ✨ Huge thanks to the amazing facilities, SQM, security, mailroom, and dock BROADIES who keep the Broad running daily. If you're a fellow Broadie, take a moment to say thanks—they deserve it! 🙌 Big thanks to @cidmarmol.bsky.social for keeping this tradition alive! 💙

Jon Arizti Sanz Imperial alumnus Jon Arizti Sanz is revolutionising the field of infectious disease diagnostics and pandemic prevention.

🎉 Huge congrats to Dr. Jon Arizti Sanz for winning the 2025 Imperial Alumni Award from his alma mater, @imperialcollegeldn.bsky.social! 👏 This award honors game-changers & problem-solvers, and Jon has been just that in the Sabeti Lab & beyond! Read more ->🔗 bit.ly/4htWbhD

@kgandersen.bsky.social I think your card was added to @bjesseshapiro.bsky.social's pile 😅 we'll send you 5 this year to make up for it 🤞

Transcript-specific enrichment enables profiling of rare cell states via single-cell RNA sequencing - Nature Genetics Programmable Enrichment via RNA FlowFISH by sequencing (PERFF-seq) isolates rare cells based on RNA marker transcripts for single-cell RNA sequencing profiling of complex tissues, with applicability t...

‼️Hot off the press‼️ @tsionabay.bsky.social and the Lareau Lab (@caleblareau.bsky.social ) at MSKCC developed an approach to enrich & profile rare cell types by combining nucleic acid cytometry with single-cell profiling. 🧬🔬 Check it out here 👉 go.nature.com/40mosQa

Red tape strangles viral surveillance programs Viral surveillance is crucial to detecting isolated disease outbreaks and preventing them from growing into epidemics or pandemics. Gaps in disease surveillance contributed to the 2020 COVID pandemic ...

Starting the year off well with a new letter 🎉
Al Ozonoff and colleagues wrote an opinion letter published in Science, urging consideration of the effects that US export regulations may have on viral surveillance programs, especially in LMICs. Check it out here 📄👀-> www.science.org/stoken/autho...

THOUSAND DAYS & PHILOMENA EROMON -- ONE TRUTH REMIX MUSIC VIDEO In celebration of the struggle we all share, and all those who are in this fight for a better world, we are pleased to share our “One Truth” remix. We first wrote the song amidst the Ebola outbreak just after ACEGID’s founding. This new version and music video were made to honor ACEGID’s (now the Institute for Genomics and Global Health) tenth anniversary. Enjoy! "One Truth" Lyrics: I’m sitting in here in this room Watching everything move I do not know how this city was built We are forsaken to the sound oh that life that goes but we were born to radiate Chorus Uhh uhh uhh uhh yeah yeah yeah yeah x 3 We are gathered on the ground waiting for a sign to arrive looking for the answers in the starry sky but we were home all along and we are the light ---we think, we speak, we walk, we breathe the air Chorus Uhh uhh uhh uhh yeah yeah yeah yeah x 3 A lifetime that we write We laugh We cry We pray We are love -- We dream We scream We strive Our hunger will never die I’m here in this fight, always Chorus Uhh uhh uhh uhh yeah yeah yeah yeah x 6 A lifetime for one for one truth That I’m alive, And so are you We are here, We are the proof A lifetime for one for one truth x 3 Website: https://acegid.org/ Instagram: https://www.instagram.com/acegid_igh/ LinkedIn: https://www.linkedin.com/company/acegid-igh/ Twitter: https://twitter.com/IGHupdates Twitter: https://twitter.com/acegid_igh

If you received this year’s holiday card, you know there’s an added bonus...✨

Celebrate 10 years of One Truth and ACEGID with the premiere of the One Truth Remix. feat. @pardissabeti.bsky.social, Philomena Eromon, & Thousand Days Band. May it bring hope & unity into the new year. ✨ 👀 bit.ly/3BCEg9o

Behind the Scenes: Creating the Sabeti Lab's Holiday Take a sneak peek into the magic behind the Sabeti Lab's holiday card! 🎄✨ A huge shoutout to our amazing holiday card crew for bringing this vision to life, and an extra-special thank you to Omayma Dalal for capturing the magic and creating this beautiful video. Happy Holidays from all of us!

✨ Get a glimpse behind the scenes of this year’s holiday card! 🎥💫 Watch the magic come to life here: bit.ly/4gFdvjp

We hope it brings a little extra holiday cheer your way! 🎄💖

What better way to kick off our Bluesky journey than with our annual holiday card? 🌟 Celebrate unity, humanity, and the milestones shaping a brighter future with us. Happy Holidays! 🎄✨ bit.ly/3Dsr6wk