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Posts by Serafeim

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The Serotonin Theory of Depression: A Systematic Umbrella Review of the Evidence | Focus The serotonin hypothesis of depression is still influential. We aimed to synthesise and evaluate evidence on whether depression is associated with lowered serotonin concentration or activity in a syst...

“The main areas of serotonin research provide no consistent evidence of there being an association between serotonin and depression, and no support for the hypothesis that depression is caused by lowered serotonin activity or concentrations”.

2 days ago 0 0 0 0
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Is a random human peer better than a highly supportive chatbot in reducing loneliness over time? AI chatbots are increasingly embedded in social life, offering accessible companionship. While brief interactions have been shown to provide immediate…

“Although our chatbot “Sam” was designed to offer consistent support rooted in principles from relationship science, interacting with this chatbot did not yield the same psychological benefits as interacting with a randomly selected first-year university student”.

1 week ago 0 0 0 0
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Stop, reduce or stay on antipsychotics after first-episode psychosis? 💊

New RCT: dose reduction raised relapse risk in year 1, but improved functioning by year 3.

The message: personalised, collaborative care.

buff.ly/3Ph5MJ9

#MentalHealth #Psychosis #Schizophrenia

2 weeks ago 3 2 0 0
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Relational Sovereignty: The Palestinian Family as a Site of Decolonial Queering This article provides the first examination focused exclusively on the family lives of queer Palestinians, moving beyond reductive Western media and pinkwashing portrayals that often spectacularize...

“This transition disrupts Zionist pinkwashing narratives by positioning the family not as an irredeemable site of repression, but as a resilient foundation for queer survival and indigenous belonging”.

2 weeks ago 0 0 0 0
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Depersonalisation-Derealisation Disorder affects around 2% of people yet there is limited guidance on treatments specifically for the condition.

A feasibility trial of Cognitive Behaviour Therapy shows promise. 🌀

buff.ly/NVEYJIH

#Depersonalisation #MentalHealth #CBT #Dissociation

3 weeks ago 2 3 1 0
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Skin-picking as self-soothing: is emotion regulation the missing piece? 🩹

Adults with skin picking (excoriation) disorder show higher emotion dysregulation 📊, lower distress tolerance 😔, and trouble naming their feelings.

Could DBT 🌱 or ACT 💬 help? 🔍

#MentalHealth #BFRB #SPD

buff.ly/96McJM2

3 weeks ago 3 2 0 0
OSF

«A mechanism-testing experiment in the UK and Western Europe (N = 943) showed that compassion drives willingness to help, but in this broader sample LGBT+ clients elicited less compassion, reducing help particularly for transgender clients».

3 weeks ago 0 0 0 0
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tCBT New Paper: The ‘Forever Fallacy’: a proposed temporal distortion in CBT

Full free text at www.cambridge.org/core/journals/the-cognit...

4 weeks ago 0 1 0 0
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Integrating Physical Activity Into Routine Psychiatric Care This narrative review synthesizes evidence on integrating physical activity and reducing sedentary behavior into adult psychiatric care for individuals with severe mental illness.

Physical activity (PA) “should be considered a core component of psychiatric care”. PA and reducing prolonged sedentary behaviour “ … can improve symptoms, enhance physical and cognitive health, and help narrow the life expectancy gap experienced by people with SMI.”

1 month ago 0 0 0 0
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🧡 Small service evaluation: 12 participants attended compassion-focused therapy groups in two CMHTs.

Some showed improvements in self-compassion and depression, but this was a service evaluation without comparison group, not evidence of effectiveness.

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#CFT #CMHT #MentalHealth

1 month ago 4 2 1 0
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Mental Disorders as Homeostatic Property Clusters This narrative review explores the idea of understanding mental disorders according to homeostatic property clusters rather than through typical classification systems.

“The homeostatic property clusters view accounts for many robust phenomena in mental health science, turning classification challenges from isolated anomalies into natural consequences of superimposing structure on the landscape of mental health problems”.

1 month ago 0 0 0 0
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Sage Journals: Discover world-class research Subscription and open access journals from Sage, the world's leading independent academic publisher.

Interesting research looking into masking and CAT-Q.

1 month ago 0 1 0 0
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💔 Boys and men take 15-20 years on average to disclose sexual trauma.

New review found masculine norms, shame & fear of disbelief create unique barriers.

Disclosure less likely when perpetrator was someone close.

Gender-sensitive support needed.

buff.ly/ELBKXzx

#SexualTrauma #MensMentalHealth

1 month ago 6 4 0 1

Yesterday the NHS banned all under 18 prescriptions of HRT for trans young people.

This ban was justified by 10 new studies that largely stated NO EVIDENCE for under 18s HRT exists.

The study underpinning this played one particular trick.

Let's briefly look at how the NHS rigged the game 1/5

1 month ago 935 431 11 47

In a competitive field where it is hard to stand out, to truly shine for national transphobia, the UK and NHS are absolutely knocking it out of the park. They looked and looked and only found 1 study on puberty blockers + oestrogen

Others try and transphobe but we are world class transphobes

1 month ago 169 50 6 0
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Leading psychiatrists are 'alarmed' that gender clinics refused to uphold really basic responsibilities of data stewardship, privacy and informed consent for research.

Trans communities do not hate research. We hate bad faith research designed to harm communities. 1/3

1 month ago 132 37 2 3

First I've seen it confirmed. Both Steensma and Kaltiala, two figures prominent in bad science re trans kids, advised the Cass Review's York Studies.

1 month ago 157 46 4 0
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Trans kids under 10: The NHS Project R22 Following a Cass Review recommendation, the NHS has commissioned a pilot (the R22 Project) for trans kids under 10. Very little information is publicly available on this pilot, with its existence f…

Trans kids under age 10 - the NHS's project R22:

New blog examining the NHS's latest pilot project on younger trans children: growinguptransgender.com/2026/03/02/t...

1 month ago 75 31 5 9
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Cognitive behavioural therapy is not universally evidence-based: implications for eating disorders - Journal of Eating Disorders Cognitive behavioural therapy (CBT) is widely described as an evidence-based psychological treatment, including within eating disorder (ED) care. However, evidence claims are only valid within the bou...

“The paper concludes that universal claims about CBT are … are better understood as population-specific evidence claims grounded in co-designed trials, culturally valid measurement, and implementation research demonstrating safety, relevance, and benefit for diverse communities.”

1 month ago 0 0 0 0
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🔴 People using mental health services experience sexual violence at substantially higher rates than the general population.

Review suggests that 13% of women, 3% of men (using MH services) experienced sexual violence in the last year.

Yet clinicians don't routinely screen.
buff.ly/ZKHuefe

1 month ago 1 2 0 0
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Facial recognition error prompts police to arrest Asian man for burglary 100 miles away Exclusive: Alvi Choudhury claiming damages against Thames Valley police after biased technology confused him with man looking ‘10 years younger’

"The technology was revealed in December to produce a far higher rate of false positives for black (5.5%) and Asian (4.0%) faces than for white faces (0.04 %) at certain settings, according to Home Office commissioned research."

1 month ago 138 47 6 6

So glad we have massively restructured transgender care on based on the works of someone who believes absolute nonsense.

2 months ago 501 121 28 9
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In a pretty grim decision - with one very considerable silver lining - the High Court has dismissed our challenge to the EHRC Interim guidance.

A number of resources follow in a 🧵.

2 months ago 305 104 29 6
The effects of screen habits on attentional skills and prosocial behaviors in 6-to 36-month-old toddlers - Scientific Reports Scientific Reports - The effects of screen habits on attentional skills and prosocial behaviors in 6-to 36-month-old toddlers

“[…] while extensive screen time can displace crucial developmental interactions and negatively impact early developmental skills, active parental involvement can mitigate these effects”.

2 months ago 0 0 0 0
Η αλληλεπίδραση θρησκείας, πνευματικότητας και στάσεων απέναντι στις τρανς και αμφιφυλόφιλες ταυτότητες: επιστημονικές ενδείξεις από φοιτητές υγείας και κοινωνικών επιστημών|Κοινωνική Εργασία. Επιθεώρ...

ejournals.epublishing.ekt.gr/index.php/so...

3 months ago 0 1 0 0
Welcome Guide - Beadnell Ward Mother and Baby Unit - Cumbria, Northumberland, Tyne and Wear NHS Foundation Trust Useful information about your stay on Beadnell Ward. It will tell you about the ward, staff and treatments and therapies that are available to you.

Cumbria, Northumberland, Tyne and Wear NHS Trust @cntw.bsky.social have you installed Oxevision on the mother and baby unit? The new ward leaflet has added information about Oxevision as well as body worn cameras. This is unspeakably unethical.

www.cntw.nhs.uk/resource-lib...

2 months ago 3 3 1 0
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Mentalisation-based treatment for antisocial personality disorder in males convicted of an offence on community probation in England and Wales (Mentalization for Offending Adult Males, MOAM): a multic... MBT-ASPD holds promise as an effective intervention for individuals with antisocial personality disorder within a forensic population. Future research should explore these findings’ generalisability a...

Great news! “MBT-ASPD holds promise as an effective intervention for individuals with antisocial personality disorder within a forensic population”

2 months ago 0 0 0 0
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‘What I see in clinic is never a set of labels’: are we in danger of overdiagnosing mental illness? Our current approach to mental health labelling and diagnosis has brought benefits. But as a practising doctor, I am concerned that it may be doing more harm than good

A good read: Gavin Francis on the current 'epidemic' in mental distress

www.theguardian.com/news/2026/fe...

#psychiatry #GPs #primarycare #lifeexperiences #diagnosis

2 months ago 4 2 0 0
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NHS closed Tavistock over care complaints – there were only eight An eye-opening FOI report has revealed that just eight people complained about the Tavistock gender clinic's care provision in 10 years.

NHS closed Tavistock over trans care concerns – there were just eight complaints
www.thepinknews.com/2026/02/11/nhs-closed-ta...

2 months ago 23 9 3 0
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Personality disorders affect 5% of the population, similar to anxiety, but don't appear in global burden of disease data. Why? 📊

Review of 60 studies, 28 countries. Higher mortality risk, especially for inpatients. Yet invisible in public health planning.

#PersonalityDisorders

🧵 THREAD

2 months ago 4 3 1 0