Thanks to all co-workers, this was a great team effort and an important part in the preparation process of @for5596.bsky.social - now happy to see the ChemBioChem view statistics.

How to Tell an N from an O: Controlling the Chemoselectivity of Methyltransferases S-Adenosyl-l-methionine (SAM)-dependent methyltransferases (MTs) are important enzymes in numerous biological pathways. They share a common SN2 mechanism but act on different nucleophilic substrates i...

If you want to know how to tell an N from an O, you can get some ideas in our new paper. This was a great team effort, introducing us to new methods: MD w/ Ferran Feixas & Marc Garcia Borràs (Girona) + HDX-MS w/ Wieland Steinchen & Gert Bange @bangebalcony.bsky.social
pubs.acs.org/doi/10.1021/...

logo of research group FOR 5596 on SAM-dependent enzyme chemistry showing the chemical structure of S-adenosylmethionine

FOR 5596 is now on BlueSky! Follow us to stay informed about our collaborative project "Unfolding the potential of SAM-dependent enzyme chemistry".

Appell für mehr Klimaschutz in den Koalitionsverhandlung

Noch bis zum 24.3. Zeit den Appell für mehr Klimaschutz in den Koalitionsverhandlungen zu unterschreiben.
www.bayceer.uni-bayreuth.de/s4f/de/top/o...

Rewiring Escherichia coli to transform formate into methyl groups - Microbial Cell Factories Background Biotechnological applications are steadily growing and have become an important tool to reinvent the synthesis of chemicals and pharmaceuticals for lower dependence on fossil resources. In ...

🖍️ We are happy to share our latest paper! Introduction of the formate assimilation from M. extorquens into E. coli allows transformation of formate into methyl groups. Renewable C1 compounds for biocatalytic methylation!
microbialcellfactories.biomedcentral.com/articles/10....