Standardizing these definitions is vital for the safety and efficacy of the next generation of SCI neuroprosthetics. 🏥🦾
Read the full review: journals.sagepub.com/doi/abs/10.1...
#SCI #MedEd #AutonomicDysreflexia #SpinalStimulation #Neuromodulation
Posts by Ryan Solinsky, MD
An “uncontrolled” Issue: Some studies include that AD is only an “uncontrolled” BP increase (and thus since they are in control of the stim, this can’t be AD). The current international consensus definition of AD does not support this language.
4/n
Measurement Bias: If you only look for symptoms (headaches, sweating), you’ll miss a lot. Symptomatic AD occurs in only 4-7% of participants, but asymptomatic BP spikes are incredibly common.
3/n
Is that spike an "off-target" complication or "therapeutic" neuromodulation?
The Threshold Trap: The 20 mmHg rule lacks a robust physiological rationale for research and often fails to account for the exercise pressor response when stimulation causes muscle contractions.
2/n
Is it "Treatment" or "Trouble"? 🔍
Our new review tackles a major debate in #SpinalCordInjury research: How do we define Autonomic Dysreflexia (AD) during spinal cord stimulation?
Currently, any systolic BP jump >20 mmHg is labeled AD. But as #NeuroTech evolves, researchers are split…
1/n
“Science not communicated is science not done”. So many key tips in here to effectively share your science and help change the world.
Defending PhD student, looking over their thesis: “If I knew then what I know now, I could’ve done all of this in like 9 months.”
A thread about my favorite pioneering cave explorers and why I don’t think AI will ever “solve” biology.
🚀 Push the frontiers of #RehabMedicine research with the AAP RMSTP!
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Thinking of writing your first big grant? Can’t recommend this program enough and learned many nuanced approaches I still use today.
medschool.cuanschutz.edu/physical-the...
AI integration in spinal cord injury medicine precourse at the ASIA2025 meeting. Led by @peabody124.bsky.social and Dr. Sarah Brueningk. Learning lessons from other successful examples in Cancer, Alzheimer’s, Cardiology.
Nature research paper: Closed-loop vagus nerve stimulation aids recovery from spinal cord injury
https://go.nature.com/4mrysC9
Yeah that was a great session from the American Spinal Cord Injury Association! If you like that session, check out the conference! :) asia-spinalinjury.org
Minnesota Neuromodulation Symposium poster session
Minnesota Neuromodulation Symposium poster session
Minnesota Neuromodulation Symposium poster session
Minnesota Neuromodulation Symposium poster session
Proud early PI moment. Lab did an amazing job presenting our new work on autonomic neuromodulation for people w/ spinal cord injury at the Minnesota Neuromodulation Symposium
Important work coming out on:
-cardiac stability w/ spinal stim
-biomarkers of spasticity
-AD during motor threshold tests
Learn how controlled breathing reduces anxiety and inflammation and how intermittent low oxygen drives plasticity and improves health at this #APS2025 game-changer session: ow.ly/kEZO50VlLfV #WeArePhysiology đź§Ş @ameuret.bsky.social
Ground breaking wireless bladder pressure monitor for real world recordings in Journal of Urology. Already yielding results, showing higher pressures during ambulation. This will change how we manage and think about bladder dysfunction after SCI.
Sponsored by the now defunded DoD SCIRP grants.
Worth a listen, new podcast from @u2fp.bsky.social with Dr. Andy Taylor on the recently disbanded $40M DoD spinal cord injury research program.
This was a unique program which ensured people impacted by SCI were helping make funding decisions based on community priorities.
u2fp.org/get-educated...
Significant functional improvements in walking speed/endurance for people with spinal cord injury with combined 4-aminopyridine and paired associative stimulation.
A great study by Dr. Monica Perez and an All Star group.
#SCIrehab đź§Ş #phySKYatry
academic.oup.com/brain/advanc...
This is really interesting & I hope it holds up to rigorous peer review.
With an intervention at 2-4 weeks after acute SCI, considering natural recovery is key. Digital twins are ideal to know typical recovery.
Dr. Bruningk’s site will be my first stop when these results hit.
hicsci.ethz.ch/tool
Implanted neural interfaces throughout the body
Are you …Ready for It? In this Era of neurotechnology, we wrote this TIMEly review of the technological and biological failure modes of implanted neural interfaces and how to overcome these challenges, Swiftly published in Bioelectronic Medicine. PS I’m so proud of these figures. rdcu.be/eduek
What a great panel!
Photo of Ben Petrie standing in front of his slide title "Gamified Electromyographic Biofeedback for People with Tetraplegia
@ben-petrie.bsky.social gave a great #physiatry2025 presentation on EMG biofeedback for people with spinal cord injury and won first prize! Thanks to the Craig H. Neilsen Foundation for support for this project, and to all of our participants.
Excited to share this soon in an upcoming manuscript!
A fun data science competition with unique dataset access for those interested in spinal cord injury research (or who just want to make the world better).
Reveal of winning team results will be a highlight of the American Spinal Injury Association precourse this June!
đź§Ş #SCIrehab #PhySKYatry
Being a person with deadly, incurable cancer who is nonetheless still alive for an indefinite timeframe gives me an interesting metaphor that helps me deal with things like large-scale corruption in government or commerce.
Bear with me for a second while I try to explain.
Every year around now, I start to see grad students on social media bemoan that they’re going home for the holidays to a family that doesn’t understand their research, or what they do in general, and it breaks my heart. 🧵 🧪 #SciComm
🔴Normally, pinkness or redness are an early indication of a pressure ulcer forming but with dark skin tones this often isn't the case. Find out more on our website⬇️
https://buff.ly/3AT1MhQ…
#STOPTHEPRESSURE #CheckEveryTone
In collaboration with @hudgellsolicitors.bsky.social
Editorial on a critical access issue for individuals with spinal cord injuries.
Despite 98% of US physicians using nitro paste as 1st line for autonomic dysreflexia management - this basic med isn’t available in Canada or Latin America.
#medSKY #PhySKYatry
onlinelibrary.wiley.com/doi/10.1002/...
Editorial on a critical access issue for individuals with spinal cord injuries.
Despite 98% of US physicians using nitro paste as 1st line for autonomic dysreflexia management - this basic med isn’t available in Canada or Latin America.
#medSKY #PhySKYatry
onlinelibrary.wiley.com/doi/10.1002/...
Think you know Autonomic Dysreflexia after spinal cord injury?
After decades of everyone doing their own thing, we’ve had 20 years consensus definition.
But it’s far from perfect. Herein we take a deep dive into where the definition fails and how it might be improved.
#Medsky #SCIrehab #PhySKYatry
🙌🏼