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Posts by Rosi Fregel

DNAharvester's workflow.

DNAharvester's workflow.

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We present DNAharvester 🎉🦴🚜🧬

A pipeline to process highly degraded ancient DNA data that integrates metagenomic filtering, competitive mapping, multiple alignment strategies, reference bias evaluation and much more.

GitHub: github.com/NBISweden/DN...

Preprint: www.biorxiv.org/content/10.6...

1 day ago 41 22 0 1

New paper alert 🚨

A study led by #CPGSthlm researchers found DNA from a bear in 9.6k year old lake sediments. This potentially rewrites the history of brown bears in Scandinavia! 🧬🐻🐾🏔️🧊

Check @officialernst.bsky.social thread 👉
bsky.app/profile/offi...

OA article 👉 www.pnas.org/doi/10.1073/...

10 hours ago 16 10 0 0

New preprint led by Hrushikesh Loya, me, and Simon Myers where we introduce GhostBuster! www.biorxiv.org/content/10.6...

The idea is to find all the different ways a target individual relates to reference groups in genealogies, to "bust the ghosts" in our ancestry.

2 days ago 35 19 1 1
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Ancient DNA reveals 4000 years of grapevine diversity, viticulture and clonal propagation in France - Nature Communications Here, the authors present aDNA from 49 grape pips spanning the Bronze Age to Medieval period in France and surrounding areas. They find evidence of long-distance exchange of domestic varieties…

On this week's #MetagenomicsMonday: #aDNA study 🧬traces the roots of French #wine! 🍇 Roman trade, clonal propagation, and even a medieval grape identical to modern #PinotNoir emerge from 4,000 years of #viticulture.
www.nature.com/articles/s41...
#SPAAM #archaeobotany #domestication #agriculture

2 days ago 5 2 0 0

Genome-wide genealogies reveal deep admixtures forming modern humans

www.biorxiv.org/content/10.6...

4 days ago 7 4 0 0
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Can you believe that until now there were more genomes sequenced for the woolly mammoth than for living African elephants?

Today, we bring you the first genomic, continent-scale analyses of 232 high-quality genomes of both species, the savanna and forest elephant.

www.nature.com/articles/s41...

6 days ago 30 10 1 2

Muchísimas felicidades María!! Más que merecido! ❤️

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Congrats Kevin!!

1 week ago 1 0 0 0
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Ancient environmental genome reveals a migratory brown bear individual in Early Holocene Scandinavia | PNAS After the last ice age, species migrated into a newly deglaciated Scandinavia. Brown bear recolonization is thought to have occurred from two direc...

Very excited to share our study of an ancient environmental genome extracted from lake sediment! It originates from a brown bear that lived around 9,600 years ago close to the last ice-sheet remains in northern Sweden, and has an unexpected mitochondrial haplogroup. 1/7 www.pnas.org/doi/10.1073/...

1 week ago 51 25 1 3
Summary chart showing mean and standard deviation of carbon and nitrogen isotope values from Swifterbant compared to human and faunal values from the Mesolithic site of Hardinxveld. One group of cows and sheep at Swifterbant displays a diet similar to humans and dogs, suggesting they were being managed by humans.

Summary chart showing mean and standard deviation of carbon and nitrogen isotope values from Swifterbant compared to human and faunal values from the Mesolithic site of Hardinxveld. One group of cows and sheep at Swifterbant displays a diet similar to humans and dogs, suggesting they were being managed by humans.

When did people in northern Europe first adopt animal husbandry? #NationalFarmAnimalsDay 🏺 #Archaeology

Isotope analysis of animal remains from Swifterbant 🇳🇱 suggests livestock management was practised in the Dutch wetlands over 200 years earlier than expected.

🆓 doi.org/10.15184/aqy...

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We are looking forward to welcoming you to Stockholm in only 83 days 😍

Our conference will be packed with exciting oral presentations 💁‍♂️, poster sessions 🧾, coffee breaks ☕, and pre-conference workshops 👷‍♀️

Take a look at the preliminary program ⬇️⬇️⬇️

3 weeks ago 19 8 0 1
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A few years ago, using palaeoproteomics, we identified a tiny hominin bone from Denisova Cave and named it Denisova 17 (D17).

A rather unremarkable sliver.

At the time, I wondered, could it be Denny’s sibling (the Neanderthal/Denisovan hybrid we had just reported)?

Well, turns out: no. 🧵1/4

2 weeks ago 57 22 3 0
Map of the Mediterranean during the Middle Ages, showing the Islamic areas of influence and Ibiza.

Map of the Mediterranean during the Middle Ages, showing the Islamic areas of influence and Ibiza.

Ricardo, lead author of the article, processing one of the samples in the lab.

Ricardo, lead author of the article, processing one of the samples in the lab.

New paper alert 🚨

Researchers at #CPGStlhm have analyzed ancient genomes from an Islamic cemetery in Ibiza (950–1150 CE) 🏖️

They found a highly diverse community with ancestry from Europe and North Africa!

The paper was published in @natcomms.nature.com

OA link www.nature.com/articles/s41...

3 weeks ago 18 9 1 1
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Out today is our paper 'Genomic history of early dogs in Europe', in which we uncover the identity of the dogs that lived in Europe before agriculture—during the Paleolithic & Mesolithic periods: doi.org/10.1038/s415.... A thread ⬇️ (10)

@biouea.bsky.social @crick.ac.uk @mpi-eva-leipzig.bsky.social

3 weeks ago 181 75 4 9
Overview of Admixture results based on genome-wide SNPs supporting four giraffe species (top)—northern giraffe (Giraffa camelopardalis), the reticulated giraffe (G. reticulata), the Masai giraffe (G. tippelskirchi), and the southern giraffe (G. giraffa)—and 7 subspecies (bottom). Colors correspond to (sub)species membership. Map of sub-Saharan Africa shows the geographic ranges of each giraffe (sub)species where colors correspond to (sub)species colors from Admixture results.

Overview of Admixture results based on genome-wide SNPs supporting four giraffe species (top)—northern giraffe (Giraffa camelopardalis), the reticulated giraffe (G. reticulata), the Masai giraffe (G. tippelskirchi), and the southern giraffe (G. giraffa)—and 7 subspecies (bottom). Colors correspond to (sub)species membership. Map of sub-Saharan Africa shows the geographic ranges of each giraffe (sub)species where colors correspond to (sub)species colors from Admixture results.

Giraffes have long necks and a long history of scientists debating their taxonomy! 1 species with 9 subspecies had generally been accepted, but whole genome data from 50 giraffes from all previously recognized subspecies support 4 species and 7 subspecies! #2026MMM doi.org/10.1016/j.cub.2021.04.033

1 month ago 28 6 0 0
Research engineer - Uppsala University Research engineer, Department of Organismal Biology, Uppsala University

The @scilifelab.se Ancient DNA Unit is recruiting a (permanent) Research Engineer for planning user projects and generating #aDNA 🧬 data:

Application deadline: March 25th 🧪🏺

www.uu.se/en/about-uu/...

1 month ago 20 31 0 0
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Really happy to share our new preprint on the co-occurrance of Y.pestis and Erysipelothrix spp. during prehistory. 🔥🔥🔥
In the study, we find the earliest evidence to date of Y.pestis in Southern Europe and 60 new Erysipelothrix genomes spanning 20k years 🦠🐄🚶‍♂️⌛
www.biorxiv.org/content/10.6...

1 month ago 9 5 0 0
Robust imputation-based method for eye, hair, and skin colour prediction from low-coverage ancient DNA Scientific Reports - Robust imputation-based method for eye, hair, and skin colour prediction from low-coverage ancient DNA

Robust imputation-based method for eye, hair, and skin colour prediction from low-coverage ancient DNA
rdcu.be/e2ODi

2 months ago 1 0 0 0
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Excited and proud 😊 to share the final chapter of @hjorvik.bsky.social 's PhD thesis:

Seven Millennia of Human Exploitation drove genomic Changes in Iberian Sheep

Comments welcome! 🧬🧪🏺🐑

www.biorxiv.org/content/10.6...

🧵(1/8)

2 months ago 40 14 1 1

The story the evolution of height in populations of Europe has been a bit of rollercoaster, veering between natural selection or admixture with populations who had a higher genetic propensity to be taller by chance. This preprint goes back to natural selection...

www.biorxiv.org/content/10.6...

2 months ago 27 7 2 0
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'Landmark' elephant bone finding in Spain may be from time of Hannibal's war against Rome An elephant bone discovered in Spain may date to the time of Hannibal's battles against the Romans.

The discovery of an ancient elephant bone in Spain is the first "direct archaeological testimony" of war elephants being used from Hannibal's time, a new study reports. 🏺🧪🐘

2 months ago 311 94 1 11

Excited to share our work on #AncientRNA from alcohol-preserved lungs, recovering the oldest human RNA virus genome (an 18th-century rhinovirus). Our study shows that viral RNA remnants persist in centuries-old tissue, opening new ways to study virus evolution and historical disease #Paleovirology🫁🦠

2 months ago 72 21 2 5
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Assessing Ancient DNA Sampling Strategies for Natural Selection Inference in Humans Using Allele Frequency Time Series Data Abstract. The increased availability of genomic data from ancient humans allows estimating the strength of natural selection at a given locus using time se

Interested in using aDNA time-series datasets to estimate selection?

Our study "Assessing Ancient DNA Sampling Strategies for Natural Selection Inference in Humans Using Allele Frequency Time Series Data" is now out in GBE! doi.org/10.1093/gbe/... @genomebiolevol.bsky.social @cegamorim.bsky.social

2 months ago 53 24 2 1

We sequenced #ancientRNA from an 18th-Century human lung and recovered a rhinovirus genome. Take a look at our preprint. Feedback welcome.

2 months ago 39 11 1 2
Bruce Springsteen - Streets Of Minneapolis (Official Audio)
Bruce Springsteen - Streets Of Minneapolis (Official Audio) YouTube video by Bruce Springsteen

I wrote this song on Saturday, recorded it yesterday and released it to you today in response to the state terror being visited on the city of Minneapolis. It’s dedicated to the people of Minneapolis, our innocent immigrant neighbors and in memory of Alex Pretti and Renee Good.

Stay free

2 months ago 97473 40806 4293 5340
Graduate School of health and Medical Sciences RadEditor - please enable JavaScript to use the rich text editor.

Registration OPEN for Practical Palaeoproteomics Summer School Copenhagen! 🦴🧪

🗓️ Aug 12–21, 2026 📍 Copenhagen (In-person + 3-day remote option) 🎓 6 ECTS credits ⏳ Deadline: April 1st

Apply here: phdcourses.ku.dk/detailkursus...

#Palaeoproteomics #BioArch #Archaeology #Proteomics #PhDLife

2 months ago 18 19 0 1
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Evidence for the earliest hominin use of wooden handheld tools found at Marathousa 1 (Greece) | PNAS The Middle Pleistocene (MP; ca. 774 to 129 ka) marks a critical period of human evolution, characterized by increasing behavioral complexity and th...

Two rare wooden tools from Greece, dated to 430,000 years ago, reveal a hidden side of early hominin technology. These fragile artifacts hint at a vanished world of organic tools that shaped daily life. #Paleoanthropology #Archaeology #HumanEvolution #Paleolithic @katharv.bsky.social

2 months ago 7 2 0 0
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Genetic Data From Over 20,000 U.S. Children Misused for ‘Race Science’

Incredibly important story that everyone should read.

These are not disorganized lone actors, but well-funded and powerful networks to be treated as serious threats.

They are using our work to push a eugenicist and racist agenda that is scientifically invalid and morally reprehensible.

2 months ago 70 43 1 8
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