Advertisement · 728 × 90

Posts by Paul Fiedler

Video

You've never seen human anatomy like this before.

Using a particle accelerator, the Human Organ Atlas is producing 3D scans of our organs in unprecedented detail! You can look through different layers of tissue and even zoom in on the cells for the heart, lungs, eyes, kidneys, and more.

1 day ago 320 77 9 12
Video

New preprint!

Prefrontal brain-to-brain synchrony during human group hunting: Evidence from fNIRS hyperscanning

Heroic work from @emre-yavuz-21.bsky.social and team

fNIRS & minecraft combined to reveal PFC synchrony during human group hunting

www.biorxiv.org/content/10.6...

1 day ago 67 19 4 1
Post image

Excited to share a new review by @kocherlab.bsky.social and me:

Nature-inspired neuroscience

We discuss diverse sensory systems and behaviors across the animal kingdom and argue for their integration into neuroscience. New tools in diverse systems are making this possible ✨

tinyurl.com/y5y9du27

2 days ago 193 70 1 8
Preview
Color Game — How Well Can You Remember Colors? We show you colors. You recreate them from memory. Challenge friends to beat your score. It's harder than you think. Play free at dialed.gg.

Visual #workingmemory peeps, you're going to love this. This is super challenging - might give you pause on how we are measuring color memory...

My color memory is a 40.4/50. Please do worse so I feel better.
dialed.gg?c=3PCHDE

3 weeks ago 61 18 19 6
Preview
When Your Brain's Immune System Burns Out: A New Way to Think About Alzheimer's Disease What if Alzheimer's isn't just about the buildup of toxic proteins — but about the immune cells that were supposed to clean them up, and why they eventually stop doing their job?

When Your Brain's Immune System Burns Out: A New Way to Think About Alzheimer's Disease
open.substack.com/pub/hyassine...

3 weeks ago 6 2 0 0
Preview
The human amygdala in threat learning and extinction Ultrasonic neuromodulation of the human amygdala provides causal evidence for its role in forming persistent threat memories.

🧠 What makes threat memories so hard to forget? 🐍😱

Using focused ultrasound we provide causal evidence that the human amygdala drives rapid threat learning 🐍⚡ and determines how resistant those memories become to subsequent extinction 🐍🚫

🆕📄 www.science.org/doi/10.1126/...

3 weeks ago 64 13 2 6
Preview
Terms of (Ab)Use: An Analysis of GenAI Services Generative AI services like ChatGPT and Gemini are some of the fastest-growing consumer services. Individuals using such services must accept their terms of use before access, and conform to these ter...

New paper from @aial.ie! @harshp.com, Dick Blankvoort, Adel Shaaban, @sashamtl.bsky.social & me

We analysed 6 GenAI ToS--finding missing info, major power imbalances & user obligations that are impossible to meet without violating the terms

arxiv.org/abs/2603.18964 & aial.ie/research/ter...

1/

4 weeks ago 175 103 2 8
Preview
Basolateral amygdala astrocytes encode anxiety states Ghenissa et al. provide evidence that basolateral amygdala astrocytes reliably encode anxiety states. Using simultaneous in vivo calcium recordings across an array of behavioral tasks, combined with g...

Incredibly proud of this paper led by @ossamaghenissa.bsky.social and @mathiasgua.bsky.social titled Basolateral 'Amygdala Astrocytes Encode Anxiety States'.
www.cell.com/neuron/fullt...
🧵 below

4 weeks ago 80 28 13 3
Advertisement
Preview
How does the cerebellum contribute to cognitive functions? The role of the cerebellum in motor functions is well understood. But why is the same circuitry engaged in functions such as working memory, language, and social cognition? This Unsolved Mystery looks...

Also out today - A quick intro piece on the role of the cerebellum in cognition. What does it do? How will we find out? This is what @actlab.bsky.social and I think the critical questions are right now. It was fun to write - especially the section on evolution....

journals.plos.org/plosbiology/...

4 weeks ago 95 40 3 4
Experimental design and task. Top left: Intracranial electroencephalographic activity, eye and body movements were recorded as participants freely walked around the room. Wall-mounted motion-tracking cameras recorded the position of on-body reflective markers. Participants also wore an eye-tracking headset to monitor saccadic eye movements. A snapshot from the eye-facing camera is shown in the bottom right. For illustrative purposes, an experimenter is shown wearing the full setup. Top right: MRI of an example participant with an implanted RNS System. Purple dots indicate the location of four electrode contacts in the left medial temporal lobe (MTL). The top left inset shows an X-ray used to localize electrode positions. Bottom left: The environment contained 20 visible wall-mounted signs and three invisible circular target locations (0.7 m diameter). At the start of the task, participants freely explored the room to locate the invisible targets; each time a target was reached, an auditory tone signaled success, allowing them to gradually learn and remember these locations through experience. The task then alternated between two conditions: “visually-cued” navigation, during which participants navigated to a wall-mounted sign (e.g., “Blue 3”), and “memory-cued” navigation, during which they recalled and navigated to the previously learned invisible targets (e.g., “T”).

Experimental design and task. Top left: Intracranial electroencephalographic activity, eye and body movements were recorded as participants freely walked around the room. Wall-mounted motion-tracking cameras recorded the position of on-body reflective markers. Participants also wore an eye-tracking headset to monitor saccadic eye movements. A snapshot from the eye-facing camera is shown in the bottom right. For illustrative purposes, an experimenter is shown wearing the full setup. Top right: MRI of an example participant with an implanted RNS System. Purple dots indicate the location of four electrode contacts in the left medial temporal lobe (MTL). The top left inset shows an X-ray used to localize electrode positions. Bottom left: The environment contained 20 visible wall-mounted signs and three invisible circular target locations (0.7 m diameter). At the start of the task, participants freely explored the room to locate the invisible targets; each time a target was reached, an auditory tone signaled success, allowing them to gradually learn and remember these locations through experience. The task then alternated between two conditions: “visually-cued” navigation, during which participants navigated to a wall-mounted sign (e.g., “Blue 3”), and “memory-cued” navigation, during which they recalled and navigated to the previously learned invisible targets (e.g., “T”).

How do MTL theta oscillations relate to eye & body movements during navigation? @suthanalab.bsky.social &co show that #theta power increases during #saccades under memory demands, linking exploratory gaze & planning to memory‑related dynamics during #navigation @plosbiology.org 🧪 plos.io/4dwJhR8

1 month ago 6 4 0 0
Preview
Episodic memory encoding fluctuates at a theta rhythm of 3–10 Hz - Nature Human Behaviour Biba et al. show that episodic memory encoding fluctuates at a theta rhythm of 3–10 Hz.

I've said it before, and I'll say it again: Cognition is rhythmic.
Episodic memory encoding fluctuates at a theta rhythm of 3–10 Hz
www.nature.com/articles/s41...
#neuroscience

1 month ago 42 8 1 0
Preview
Repeated Viewing of a Film Clip Changes Event Timescales in The Brain Many everyday experiences share a recurring structure: routines, familiar routes, rewatched films, and replayed songs. How do repeated encounters with such structure alter the brain’s representations ...

How do the brain’s event representations change as we gain familiarity with an experience?

Brain regions’ representations can become coarser or finer as events become familiar. Slow-timescale structure predicts memory.

Excited to share this work w/ Narjes Al-Zahli & @chrisbaldassano.bsky.social!

4 weeks ago 107 39 0 1

1/8 New preprint alert!

How are signals from the heart encoded in the brain?
What could be the functional implications of cardioception?

We found that neurons in the posterior insular cortex are precisely tuned to heartbeats, and that this cardio-insular coupling supports emotion coding in mice.

4 weeks ago 87 39 2 5
Preview
Effects of Ultra-short Offline States on Item-level Verbal Memory Abstract. Memory is consolidated during “offline” states of reduced attention to the external stimulus environment, including sleep and resting wakefulness. While consolidation is usually studied on a...

When it comes to memory, not all forms of wakefulness are created equal.

Our latest:

4 weeks ago 14 3 0 0

#NeuroJobs

4 weeks ago 0 0 0 0
Post image

In a low stakes, artificial factorial experiment employers do not discriminate against immigrants.
But when it is about actually hiring people, employers do prefer applicants with German-sounding names in the same experimental choice set.

1 month ago 33 7 2 0

you say "i asked chatgpt"
i hear "i asked [an improv comedy group]"

an improv group wrote this report
instead of a therapist i use an improv comedy group

9 months ago 2233 730 41 50
Advertisement
Preview
Python metabolomics uncovers a conserved postprandial metabolite and gut–brain feeding pathway - Nature Metabolism Leveraging pythons as an extreme model of feeding and fasting behaviour, this study uncovers para-tyramine-O-sulphate as a conserved postprandial metabolite that links nutrient intake to energy balanc...

Open access link to new study in Nature Metabolism:

Python metabolomics uncovers a conserved postprandial metabolite & gut–brain feeding pathway.

🧪🐍
www.nature.com/articles/s42...

1 month ago 5 2 0 0
MEEP – Heidelberg Summer School on Memory and Sleep Join our 4-day summer school on memory consolidation, neural replay, and sleep. May 31–June 3, 2026 in Heidelberg. For Master, PhD students & postdocs.

Registration open 🎉

MEEP – Heidelberg Summer School on Memory and Sleep

www.zi-mannheim.de/forschung/ab...

1 month ago 20 19 0 3
Preview
22 years of Brain Science: what CoSyNe tells us about the evolution of Neuroscience Tracking the intellectual DNA of Computational and Systems Neuroscience through its flagship meeting

I tracked every keyword in 22 years of Cosyne abstracts to map how computational neuroscience evolved — from Bayesian brains to neural manifolds to LLMs — and where it's heading next.

1 month ago 159 70 7 18
Keep calm and be transparent: advice from scientists who retracted their papers Retractions correct the scientific record, but they have stigma attached to them. Some in the research community want that to change.

We're thrilled to announce the Ctrl-Z Award, a US$2,500 prize for researchers “who discover substantial errors in their published work and take meaningful steps to correct the scientific record."
Covered by @nature.com today; read more here: centerforscientificintegrity.org/2026/03/10/a...

1 month ago 471 194 6 22
The Academic Wheel of Privilege showing the 24 socio-cultural identities. The 24 socio-cultural identity types span six sectors: health and wellbeing, society, culture and communication, gender and sexuality, education and career, living arrangements and lastly childhood and development. These identity types are shown as circles connected to three concentric rings (outer, middle and inner) of “identity” circles with increasing privilege as you go towards the centre.

The Academic Wheel of Privilege showing the 24 socio-cultural identities. The 24 socio-cultural identity types span six sectors: health and wellbeing, society, culture and communication, gender and sexuality, education and career, living arrangements and lastly childhood and development. These identity types are shown as circles connected to three concentric rings (outer, middle and inner) of “identity” circles with increasing privilege as you go towards the centre.

Out now!

The Academic Wheel of Privilege 🎡

We developed a framework & app to guide authorship teams in making equitable and thoughtful authorship decisions.

@saralilplants.bsky.social, @justinsulik.bsky.social, Bethan Iley, Mahmoud Elsherif, @flavioazevedo.bsky.social

🔗 osf.io/preprints/me...

1 month ago 63 37 1 6
Preview
Deltaviruses spread through a viral Trojan Horse Hepatitis D-like satellite viruses, known as deltaviruses, have been recently discovered in a wide range of animals. These viruses are thought to expr…

We found a viral Trojan Horse: a virus can hide inside another virus.This one surprised us: deltaviruses don’t just borrow a helper virus. They can travel inside it.
A literal Trojan Horse “virus-in-a-virus” route into cells. 🤯 Kudos to 1st author @viroscope.bsky.social and co-authors !

1 month ago 200 98 8 15

These reviews on neural manifolds are super relevant to today’s world of large-scale population recordings. How do we link circuits, population geometry, dynamics, and function?

“A neural manifold view of the brain” from Perich, Narain, and Gallego 2025

www.nature.com/articles/s41...

(1/2)

1 month ago 37 10 2 0
Advertisement
Preview
Interbreeding between Neanderthals and modern humans was strongly sex biased Sex biases in admixture and other demographic processes are recurrent features throughout human evolution. For admixture between Neanderthals and anatomically modern humans (AMHs), sex bias has been p...

Many living people carry fragments of Neanderthal DNA, remnants of ancient interbreeding events, with uneven distribution across chromosomes. New work by @sarahtishkoff.bsky.social lab suggests patterns are most consistent with Neanderthal contribution to human populations being highly male biased.🧪

1 month ago 57 25 5 0
Post image

1/9 New paper with @gonzalezgarcia.bsky.social and @lindedomingo.bsky.social : “Characterising semantic prioritisation in visual working memory.”
Core question: when we hold visual info briefly in mind, what gets accessed first: perceptual details or semantic meaning?

1 month ago 33 10 1 1
Post image

198 effect sizes in ego depletion resesrch showed an effect size of d=0.62. Preregistered large replications (including some by original authors) yielded an effect size of 0. No one has been able to offer any other explanation for this huge research waste than massive p-hacking.

1 month ago 135 46 6 8

#neurojobs

2 months ago 0 0 0 0

#neurojobs

2 months ago 0 0 0 0

#neurojobs

2 months ago 0 0 0 0