The Role of BAZ2-dependent Chromatin Remodeling in Suppressing G4 DNA Structures and Associated Genomic Instability DNA G-quadruplexes (G4s) are secondary structures with significant roles in regulating genome function and stability. Dysregulation of the dynamic formation of G4s is linked to genomic instability and...

Excited to share our latest preprint describing how BAZ2 chromatin remodeling suppresses G4 DNA formation and the genomic instability that occurs in its absence! Great collaboration with the Reed lab at Cardiff University and @simonelsasser www.biorxiv.org/content/10.1...