Screenshot of Science commentary articleL Scientists stunned by ‘fundamentally new way’ life produces DNA.
Newly discovered bacterial defense system challenges genetic code’s central dogma. Image: In a newly discovered bacterial defense system, paired strands of DNA (orange and cyan) are synthesized by two enzymes: One (yellow) uses an RNA template (beige) to guide the assembly of the nucleotide bases that make up DNA, while a second, highly unusual enzyme (light blue) uses its own amino acids as a template."
As a scientist, I am here to report that this headline is indeed accurate as I am in fact STUNNED!!
Wow. This is incredible. 🧪
"Newly discovered bacterial defense system challenges genetic code’s central dogma.":
www.science.org/content/arti...
4 days ago
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$2.45 billion NIH grant cuts and ~2300 terminated active research grants were DOGE'd in early 2025
Who were most affected?
www.pnas.org/doi/full/10....
Early career and women researchers
4 weeks ago
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No evidence for quorum sensing during egg hatching in the cestode Schistocephalus solidus
Schistocephalus solidus, a parasitic cestode with a multi-host life cycle, reproduces in its terminal host either by outcrossing with similarly sized individuals or selfing. Previous work found that s...
A few years ago an undergrad designed & executed an experiment to test quorum sensing in Schistocephalus. Today we published it in @peerj.bsky.social. I’m excited to see this work come to fruition & proud that we published a null result in a respected academic journal
peerj.com/articles/206...
2 months ago
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It’s a bit late, but thank you @wisconsinevolution.bsky.social for inviting me to present at the Evolution Seminar Series! It was my first seminar and I had so much fun discussing how we can integrate epigenetics with current evolutionary theory
5 months ago
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I really love Figure 1E! It’s super interesting to see how the literature across time coincides with the way people talk about this debate. I remember some of my undergraduate profs being passionately team ctenophore in 2017
5 months ago
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The sponge-ctenophore debate was one of the first that excited me as an undergrad. It’s so cool to still see new papers coming out on the topic!
5 months ago
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2 years ago the first PhD student from my lab graduated. Last week we submitted his second chapter for review, a project that we collaborated on from start to end after the two of us independently converged on the same idea to test thermal tolerance in benthic & limnetic stickleback
6 months ago
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Heritable differences in metabolic stability underpin thermal tolerance of threespine stickleback (Gasterostues aculeatus) ecotypes www.biorxiv.org/content/10.1101/2025.09....
7 months ago
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I'm dissecting a fish under a dissecting scope. I'm wearing a light blue dry suit and gloves. The dissection table is in a wood garage. There's a white pickup truck parked behind me and moose and deer antlers on the walls.
I'm working in a fume hood with a student. We're both wearing lab coats and safety glasses. We turned around and are smiling at the camera.
I wrote an op-ed on the importance of federally funded science for my hometown newspaper as part of the #McClintockLetter initiative. Thanks
@cornellasap.bsky.social
for organizing this initiative! Here's some action shots of NSF and NIH funded science. www.tbnweekly.com/opinion/arti...
9 months ago
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Four photos for the four research jobs I’ve had. Two as an intern for the NPS and USFS, one as a USFS employee, and one as a NIH and NSF-funded grad student. The future is uncertain, but I love doing science and I don’t plan to stop
1 year ago
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Early Career Award Seminar
The J.F. Crow Institute for the Study of Evolution at the University of Wisconsin-Madison is inviting early-career evolutionary biologists from outside UW-Madison to apply to participate in an early-c...
Wisconsin Evolution is accepting applications for Early Career Awardees! Please pass this along to any PhD students or post docs who may be interested in visiting UW-Madison to give a guest lecture at our Evolution Seminar Series
evolution.wisc.edu/seminars/ear...
1 year ago
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New preprint up! We sequenced hundreds of samples from across one of Earth's oldest living organisms - the Pando aspen clone - to understand how mutations accumulate and spread in long-lived clonal organisms. Our results were…surprising. 1/30
1 year ago
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NSF GRFP changed the submission process so that letters of rec. are due ~10 days BEFORE the student application deadline. So dumb.
Students need to start their submissions so the recommenders will be notified by NSF about the request.
Hyp.: # of 2023 applications > # of 2024 applications
1 year ago
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Excited to share a new preprint:
biorxiv.org/cgi/content/...
In 2019 we founded 9 whole lake populations of stickleback, as part of a massive eco-evo experiment. Here, we report the first half decade of host-parasite & immune trait dynamics...
(thread, 1/N)
1 year ago
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It was cool to arrive in AK after driving for 3 days (from BC) to then receive an email indicating our paper describing the big Alaska stickleback experiment is out.
onlinelibrary.wiley.com/doi/10.1002/...
1 year ago
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microPublication - Get Your Data Out, Be Cited
Do you work in ecology/evolution? Did you do a study that is too small to publish as a full manuscript? Negative results? Part of a larger effort? Consider publishing in microPublication Biology: EEB!
www.micropublication.org/journals/bio...
Short papers, one figure. And we peer review! Please RT
1 year ago
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The 2024 AGA Awards round is open!
Evolutionary, Ecological, and Conservation Genomics (EECG) Research Awards to grads & postdocs. Up to $6,000 to conclude genomic research projects and prepare results for publication.
More info at www.theaga.org
Deadline: Midnight EST, 13 Dec 2023
2 years ago
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More than bad luck: Cancer and aging are linked to replication-driven changes to the epigenome
Cellular replication leaves an epigenetic fingerprint that may partially underly the age-associated increase in cancer risk.
"Coincidently, the DNAm changes observed in aging, cancer, and proliferation share some notable patterns. In general, they tend to be characterized by gains in methylation at promoters (...) and loss of methylation in intergenic regions and repetitive elements"
2 years ago
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Neat! Identifying genes that underlie the development of sensory legs in sea robin.
2 years ago
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