Yesterday was #purpleday, the global epilepsy awareness day. Learn about mechanisms of seizure occurence in epilepsy with a 2-minutes Spikeling workshop ! #Neuroscience #Education #Epilepsy

See how we explore neuronal logic with a quick Spikeling circuit workshop — Part 1. #LogicalGating

Spikeling brings these core principles of neuronal computation, at the intersection of neurophysiology and computer science.

At the intersection of neurophysiology and computer science, studying these mechanisms benefits from close collaboration between experimentalists and computational scientists. #Neurophysiology #ComputerScience

Neural circuits combine inputs and gate signal propagation, shaping how information is transmitted and transformed. #NeuronalCircuits

Neural computation emerges from physical processes in biological circuits.

#Neuroscience #ComputerScience #NeuronalCircuits

We hope to integrate Spikeling workshops as a complement to electrophysiology lectures in neuroscience and biomedical sciences programs, to offer hands-on experience to the whole classroom, instead of just for a few students lucky enough to get an internship with wet-lab experience. #CalciumImaging

Spikeling sparked lots of interest and discussions on how it modernise the way we teach electrophysiology for neuroscience and biomedical students.
#STEM #Education #Electrophysiology #Innovation

Yesterday for
@opensourceneuro.com , Paul Rignanese was presenting a poster and a live demo of Spikeling at the Institute for Neuroscience and Cardiovascular Research Early Career Researcher Day at the The @edinburghuni.bsky.social !

#Neuroscience #BiomedicalSciences

- Signal preprocessing, see how to handle different types of noise and cleanup your data before extracting spikes.

Stay tuned for advancements ! #Neuropixel

See how your Spikeling neuron firing action potentials would look like in a extracellular ephys setup live. Features :

- Spatial integration, see how the electrode placement relative to the neuron impacts the extracellular field recordings, determining for spike sorting. #Ephys

Spikeling v3 feature reveal : a new module ! After current clamp, voltage clamp, calcium imaging, we are implementing an extracellular tetrode recording module ! #Neuroscience #CalciumImaging

This workshop is meant to act as a facillitator to fuel collaboration between behavioural and neuronal research, an essential aspect of neuroscience.

Thanks to everyone involved ! #CalciumImaging #Neuroscience

Spikeling allows people from outside the field of Neurophysiology to grasp essential concepts such as membrane voltage dynamics, synaptic integration, patching electrophysiology, calcium imaging, and have a better understanding to relate with the electrophysiology team.

Today with the Kind Lab affiliated with the Simons Initiative for the Developping Brain @sidb-edinburgh.bsky.social at the University of Edinburgh @cmvm-edinburghuni.bsky.social, we ran a Spikeling workshop with the ethology team within the lab.
#Electrophysiology

Interplay of behaviour and neurophysiology is at the core of neuroscience, and collaboration of ethologists and neurophysiologists is crutial. #Ethology #Neurophysiology

A simple floor map (hand → spinal cord → brain) and real-time spike activity the young students could see and even hear.

A practical way to show what neurons do and what neurophysiology researchers measure.

#NeuroscienceEducation #Neurophysiology #TReNDinAfrica

Last summer in Ghana, during a @TReNDinAfrica outreach event in the exchange program between the VIB-KU Center For Neuroscience @vibneuroleuven.bsky.social and the University of Ghana, we used Spikeling to show pain propagation mechanisms to kids -

OSN promotes neuroscience access with open, low-cost tools for education, training, and outreach, especially where conventional neurophysiology setups aren’t available.

#ScienceOutreach #OpenScience

This supports state-of-the-art teaching goals: quantitative, reproducible, experiment-driven training without requiring access to expensive wet-lab infrastructure. #Neurophysiology #Electrophysiology

Students can test how sampling, kinetics, saturation, noise, and bleaching shape what imaging “means,” then export traces for standard analyses and spike inference. #TwoPhotonImaging

Spikeling’s imaging simulation brings microscopy-grade data interpretation into the classroom by linking Vm/spikes to Ca²⁺ and fluorescence (F ; ΔF/F) in real time.

#Neuroscience #CalciumImaging

Contact us to implement Spikeling practicals at your university !
#Neurophysiology #TwoPhoton
#ComputationalNeuroscience #OpenScience #OpenHardware

Spikeling also links ephys “ground truth” (spikes/Vm) to modern imaging:

its two-photon simulation generates a fluorescence/calcium-style readout, helping students interpret 2-photon data and analysis choices when working with open resources (e.g. @Allen Institute datasets).

- but have never had the opportunity to observe or record neuronal responses in an experimental setting.

Spikeling changes that.

Around laptops and devices, students run electrophysiology-style protocols: shaping inputs, tuning frequency/intensity and see firing dynamics evolve in real time.

State-of-the-art neuroscience education shouldn’t depend on access to patch-clamp rigs or two-photon microscopes.

At the @trendcamina.bsky.social computational neuroscience & ML workshop feat. @akoumoundourou.bsky.social, students arrive with strong coding skills -

#NeuroscienceEducation #CAMINA

See how we can approach the mechanisms of seizure occurence in epilepsy with a 2-minutes Spikeling workshop ! #Epilepsy #Seizure #Neuroscience #Electrophysiology #Neurophysiology

POV : unboxing a Spikeling delivery from @opensourceneuro.com ! #Neuroscience #Education #STEM #Electrophysiology #Neurophysiology #Opensource #Spikes

Finish like a real practical: built-in tools for stimulus alignment, spike detection, and averaging—a complete experiment from stimulus to analysis, in the classroom. #Education #STEM

Flip the input polarity to teach ON vs OFF pathways (responses to light onset vs offset), then tune decay and recovery to demonstrate adaptation and sensitivity reset. #NeuroPhysiology #ElectroPhysiology #Teaching