1 in every 10 women suffer from endometriosis and there is significant delay in diagnosis and there is no good treatments.
Read more about the basics if this deadly disease here
fertilityscienceresearch.org/a-primer-on-...

#endometriosis #endometriosisawareness #infertilityjourney #painmanagement

Spatial and temporal changes in the expression of steroid hormone receptors in mouse model of endometriosis Endometriosis is recognized as a steroid hormone-dependent disorder. However, controversies exist regarding the status of the steroid hormone receptor expression in endometriotic tissues. The purpose of this study was to determine the ontogeny of ...

March is Endometriosis Awareness Month
Here are some papers on endometriosis in mouse

Steroid receptors
pmc.ncbi.nlm.nih.gov/articles/PMC...

Estrogen
doi.org/10.1007/s120...
Inflamation
doi.org/10.1007/s120...
Hox genes
journals.lww.com/fsar/fulltex...

#ReproductiveBiology

March is Endometriosis Awareness Month
Much of our knowledge on endometriosis also comes from animal models.
Our work and others show
Hormonal resistance, persistent inflammation and fibrosis as the key.
#Endometriosisawarenessmonth #Endometriosis #Fertility #Infertility #MedTwitter #Scicom

Implantation is not just attachment—it’s a coordinated cellular dialogue between embryo and endometrium.
We are only beginning to understand its complexity.
#Implantation #Fertility #IVF #ReproductiveBiology #Infertility #Science #india

#Endometriosis is one of the most misunderstood disorders in reproductive health.
Despite affecting millions, we still: Diagnose it late
Treat symptoms and not causes and this is not just a clinical problem it is a scientific gap.
#EndometriosisAwarenessMonth #ReproductiveHealth #WomensHealth #MedEd

Watch till the end for the special tributes
From 2004 to today the faces have changed, but the fire remains the same. This is a tribute to the incredible women who have been the backbone of this lab for over 20 years. see the evolution of our #LabFamily
#womensday #givetogain #WomenInSTEM #iwd2026

Super elated to share our preprint on a new #PlacentaOnChip model that is 1) Scalable, 2) Microfluidics-free & 3) High-throughput capable
Proud of the hard work by Anshul and Sourav done in collab with Abhijit at IITB
#organonchip #NAMS
biorxiv.org/content/10.648…www.biorxiv.org/content/10.6...v1

Elated on the publication of my book chapter on spermatogenesis in the prestigious book on Assisted Reproduction by Dr Gautam Allahabadia
Big shout out to my co author Indrashsis

2 new studies from the lab show that early pregnancy needs inflammation but only briefly. When uterine inflammation does not activate in time, implantation fails and if prolongs pregnancy is lost.
Links
doi.org/10.1093/reprod…
doi.org/10.1016/j.lfs.���
Super proud of my team

Republic Day Greetings

The IBEX KB provides several ways to contribute and use data.

The IBEX Knowledge-Base is setting a new standard for reproducibility in #immunofluorescence imaging: open, community-driven, and with ‘exceptional’ evidence of its utility.

It’s now up to the community to contribute to its growth.

🔗 buff.ly/klv0TSF

Common variation in meiosis genes shapes human recombination and aneuploidy - Nature Analysis of data from pre-implantation genetic testing sheds light on the genetic basis of meiotic-origin aneuploidy, the leading cause of human pregnancy loss, identifying common genetic variants ass...

Regulation of embryonic ploidy by meiotic recombination.. expected ? Unexpected?
www.nature.com/articles/s41...

WHO statement on notification of withdrawal of the United States WHO regrets the United States’ notification of withdrawal from WHO – a decision that makes both the United States and the world less safe. The notification of withdrawal raises issues that will be con...

WHO statement on notification of withdrawal of the United States share.google/nfdhuCJAQrzW...

Loss of HOXA10 activates NLRP3 for epithelial plasticity and pyroptosis in endometrium during embryo implantation In briefA successful pregnancy begins with embryo implantation, but how the embryo breaks through the endometrial lining is not understood. Here, we uncove

Elated to share the publication of our paper on how HOXA10 controls NLRP3 to drive #hybridEMT and pyroptosis for embryo implantation
#Inflamation #pregnancy #reproduction

academic.oup.com/reproduction...

Genome Shows no Recent Inbreeding in Near-Extinction Woolly Rhinoceros Sample Found in Ancient Wolf's Stomach Using temporarily spaced high-coverage ancient genomes, we can assess population decline prior to extinction. However, finding suitable ancient remains for recovering this type of data is challenging. Here, we sequenced a high-coverage genome from ...

Woolly Rhino was not experiencing population decline prior to its rapid extinction ~14,000 years ago, based on DNA recovered from mummified wolf stomach in Siberian permafrost. Instead, extinction likely due to rapid environmental change.

🧪🌎🧬🖥️ #EvoSky #Genomics

pmc.ncbi.nlm.nih.gov/articles/PMC...

Tylenol during pregnancy is safe without increased risk of autism, ADHD, or intellectual disability of offspring
A new review of the evidence just out
www.thelancet.com/journals/lan...

The serenity of the city called Bhubaneswar

Biophysics of organoids In this review, Weichselberger, Moore et al. discuss how physics-based approaches illuminate organoid development and homeostasis by integrating mechanical, chemical, and informational processes. They...

Interested in the biophysics of organoids? We just published a review in Dev Cell—take a look! dlvr.it/TPyTb8 #Organoids #Biophysics

All-in-one Single-Cell Proteomic Analysis of Protein Alterations in Human Oocytes Undergoing in Vitro Aging www.biorxiv.org/content/10.64898/2026.01...

Indias position statement on the use of niPGT for clincial use is published in JHRS and covered by the media
#ivf #fertilityclinic
#embryo
#genetics
www.ndtv.com/health/india...

Temporal control of decidual inflammation by HOXA10 is essential for implantation and its dysregulation is associated with early pregnancy loss Successful implantation requires tightly regulated endometrial inflammation. While initial inflammatory signaling is essential for implantation, persi…

The year 2026 opens with a bang
Thrilled to share the publication from the lab showing that an inflammation is essential for embryo implantation
#fertility #miscarriage #uterus #infertility

www.sciencedirect.com/science/arti...

The year closes with a key policy paper.
India issues its position statement on non-invasive PGT (niPGT). Based on available data of 3000 embryos an expert review panel concludes that niPGT is not ready for clinical use for embryo selection.

journals.lww.com/jhrs/fulltex...

Exclusive: the most-cited papers of the twenty-first century A Nature analysis reveals the 25 highest-cited papers published this century and explores why they are breaking records.

Techniques, methods papers and software papers are bound to be higher on scoreboards and there are no prizes for guessing that. For which direction the science is moving .. ideal would be to look at highly cited original papers and look at field normalised citations.
www.nature.com/articles/d41...

The sun kissed evening.
Chasing the sun across the horizon. Watching the world trade its gold for midnight sapphire at 30,000 feet. There’s a certain kind of magic between sun, clouds and the sky.
​#WindowSeatViews
#DuskTillDawn
#SkyAesthetic
#GoldenHourMagic
#HorizonLines

Fantastic insights on how replication stress drives cell differentiation by Osvaldo Contreras at the joint meeting of the #InSDB and International Society of Differentiation #ISD joint meeting at #IISER_BERHAMPUR
@osvaldoics.bsky.social
#INSDBISD2025

This is just is just the tip of the iceberg ... Much more mess is around

The much awaited joint meeting of Indian Society of Developmental Biologiy #InSDB and International Society of Differentiation #ISD and has begun and excited to be a part of it. I will be taking on Wednesday Dec 17 2025 about our work on embryo implantation

Elected at the executive council of Society for Reproductive Biology and Comparative Endocrinology #SRBCE
Looking forward to ser6ve the society and taking Indian science to the international map

Deciphering mechanisms leading to preterm birth through post-GWAS integration of multi-omics data Clinical genetics; women's health; omics

www.cell.com/iscience/ful...

Batch 1 and batch 2 to off to IISER Bherampur for the coveted and much awaited meeting of the Indian Society of Developmental Biologist #InSDB 2025
Excited to present our groups work on embryo implantation and placental organ on chip and placentoids models