New lab photo! We missed 4 members today but we celebrated Jose’s one year anniversary in the lab 🥳

Congratulations!

Visualizing suborganellar lipid distribution using correlative light and electron microscopy - Nature Cell Biology Lennartz et al. introduce a correlative light and electron microscopy workflow, Lipid-CLEM, combining near-native lipid probes and on-section labelling via click chemistry. Lipid-CLEM quantitatively a...

www.nature.com/articles/s41...

Decoupling phase separation and fibrillization preserves activity of biomolecular condensates - Nature Communications The authors show that aging of metastable protein condensates can lead to amyloid formation and impair biochemical activity. Certain small molecule metabolites can selectively impede this transition, ...

www.nature.com/articles/s41...

Neurodegeneration risk variants promote lysosomal TMEM106B fibril accumulation.
🔥 preprint by former trainee extraordinaire, Jordan Marks, and the Petrucelli and Ward labs
www.biorxiv.org/content/10.6...

MitoTracker transfers from astrocytes to neurons independently of mitochondria The mitochondrial dye MitoTracker is commonly used to investigate intercellular mitochondrial transfer (IMT), particularly between astrocytes and neurons. Hole et al. compare MitoTracker with a geneti...

www.cell.com/cell-reports...

Protocol for automated analysis of biological images using Python code Image analysis in Python provides greater flexibility and an open-source alternative to commercially available software. In this protocol, we present …

New publication from our lab! We developed Python based pipelines for the analysis of confocal images. This protocol paper is tailored to a biologist without much coding experience. It is the resource I wish I had when I first started this line of work. www.sciencedirect.com/science/arti...

A still satellite image of the blizzard of 2026 in the Northeast United States. This image contains the GeoColor product from the GOES-19 weather satellite from the evening of 2026-02-23.

A view we will not soon forget.

The Blizzard of 2026.

Congratulations to our undergraduate student, Neeharika, for winning a competitive Aresty research grant!!! 🥳 This is the 6th student award from our lab within less than 1 year ☺️

Please spread the word: the Structural Studies Division @mrclmb.bsky.social is looking for a new tenure-track, independent group leader with an exciting plan in any area of Structural (Molecular & Cell) biology, in discovery biology and/or methods development. 🥳

mrc.tal.net/vx/mobile-0/...

@zs-biophys.bsky.social we also got one!

Midnight confocal session 🔬

Why cancer can come back years later — and how to stop it Researchers are targeting dormant tumour cells that might explain why some cancers reappear long after successful treatment.

Understanding why cancers relapse - sometimes years or decades after successful treatment - is a major challenge in the cancer field

This perspective in Nature discusses several of the important recent advances and new studies in the field of tumor dormancy 🧪⚕️

www.nature.com/articles/d41...

And difficult to get 😂 I managed to get it from the official tik tok shop.

Here is our lab’s mascot!

@zs-biophys.bsky.social I had the privilege of meeting this avatar today 😂

Defining RNA oligonucleotides that reverse deleterious phase transitions of RNA-binding proteins with prion-like domains RNA-binding proteins (RBPs) with prion-like domains (PrLDs), such as FUS and TDP-43, condense into functional liquids, which can transform into pathol…

www.sciencedirect.com/science/arti...

Happy new year! I've so enjoyed the end-of-year lists of people's favorite papers from 2025, so I made a list of 16 #lipidtime studies from 2025 that I found interesting. Here they are in no particular order (please add more if you would like!), and here's to much more exciting science in 2026! 🧪

NYC Part 3

NYC part 2

Museum of Modern Art, NYC

Thank you, this is very helpful!

Do they also announce the scores for the middle 1/3rd of the grants? Or just for the top 1/3?

Of course the lab flooded on the last day of experiments before the holidays 😂 🐠

Organelles do NOT have a single uniform pH.
And if you think they must, because “protons diffuse fast,” this paper is for you.
A thread on why that assumption is wrong; and what we found instead. 🧵 1/n

The lab's posters at the CellBio conference 😁

EMBO reception at the Pennsylvania academy of the fine arts 🎭

Philadelphia

Congratulations to our undergraduate student, Maia Wang, for winning the first prize in the brain art competition at the Rutgers brain health institute annual symposium for her watercolour of an axon! Great job to all our lab members who submitted 5 fantastic pieces 🖼️

New York