Enshitification is getting out of control. Juli cut the final “in credit” joke of a show to shove the next episode (or to put a big still of a show I am not even watching).
They keep hiking prices for an even shittier experience. This has to stop at some point. I already cut a few services. 👎
Finished!
Protein biologists around the world to the rest of us:
HAHA SUCK A DICK CENTRAL DOGMA 🧪
What are good and reliable open source email applications for macOS as alternatives to outlook? Ideally with calendar incorporated but ok if just email.
I am migrating to open source due to privacy and bullshit issues. Already working with LibreOffice and LibreWolf.
A barge climbs the Mississippi at sunset, New Orleans
One can only hope. Not bc government is using it, but perhaps it will fund groups to develop more user friendly Linux or open source stuff and higher outreach for the everyday user (some people just use MS bc is the only thing they think it will be compatible or just bc works gives them license)
I was thinking along the same line about Germany ditching Microsoft and working on an open source platform and France ditching Microsoft to embrace Linux.
This could mean an improvement in open source office software with potential wider adoption. Good outcome coming from all the bad stuff around.
Crocheted cat head.
Crocheted cat head
Celebrating when good things happen to good people (feels like a rare event lately) by making a cat.
Two panel comic. Panel 1: a digital kiosk at the entrance of a parking garage with a dispensed ticket. The screen display reads: PLEASE TAKE TICKET BELOW. Panel 2: a T-Rex is sticking its little arm out the window of its partially opened car door, trying to reach the ticket.
If I am going to pay $3000 to give scientific journals my research results for publication, it would be great if the submission process is not a nightmare where I have to jump through hoops that were set on fire. The process is already long. No need to add unreasonable constraints. 😠
Macos: i have no idea where your document is
Windows: “your” document? These are onedrive’s documents
Linux: /opt/fakevm/mounted/tmpfs/vmlinuz/ubuntu-36.0.01_x86_also-arm.0.21.013/snapd/docx-exporter.sx/0028492748901.txt.converted.bak/v/9/ms/1/0.out
Verge headline: I saved a doomed Windows laptop by embracing Linux by Stevie Bonifield Photo of an old ThinkPad opened to The Verge website
If your laptop is stranded on Windows 10, the solution isn't a new laptop. It's a new operating system.
Read more from @steviebonifield.bsky.social: www.theverge.com/tech/905946/...
The moon rises over St Francis of Assisi Church, State street, New Orleans
I am old enough to remember that what we call "subscription model" now used to be called "ransomware" before. What we call "updates" now used to be called "spyware" back then. That's why you no longer hear about the need to buy anti-spyware software anymore.
#enshitification
Oh to be a little Tardigrade walking around a microscopic volvox algae colony. 🫧🐻🧪
Genome sequence of a 5,000 year old bacterium (Psychrobacter) from cave ice contains more than 100 genes associated with antimicrobial resistance 😳
www.frontiersin.org/journals/mic...
Rain puddle reflection, Chartres street, New Orleans
Above the rooftops, St Augustine and the Cathedral keep each other company, New Orleans
These are not unintended consequences of their vote. That’s what they voted for. They would rather have hospitals close than seeing another brown physician with an accent.
Clouds over Bourbon, New Orleans
A second line passes by Our Lady of Good Counsel church, Felicity street, New Orleans
Carpenter bug on top of stone
The top of my dracaena plant fell down for no reason. When I looked inside the trunk, there was a bug buzzing that barely fit there 😱😱😱
It was the weirdest 80s witchcraft satan movie I’ve seen in real life (like the spider crawling out of the cheek in “the believers”). 😱😱
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Sunset with castle, Irish Bayou, New Orleans
Postage has been increasing by a lot since last year. During the first T admin you could mail something to CA for $6, now is almost $9 with the highest increase in the last year.
Two crosses on the moon, Holy Name of Jesus Church, New Orleans
Trends in transcript diversity as a function of effective population size proxy, ω (the rate of protein evolution controlling for the background rate, employing conserved single copy genes). Top: Transcript diversity as regards alternative splicing (AS) frequency. Bottom left: Transcript diversity as regards alternative polyadenylation (APA) usage. Bottom right: Transcript diversity as regards alternative transcript initiation (ATI) usage. Diversity is defined as the proportion of the transcriptome for each gene that is not the most abundant “canonical” form. For each figure, N is the sample size, ρ the Spearman rank correlation, P, the significance thereof and PPGLS, the significance of the correlation allowing for shared ancestry.
While it's tempting to suppose that everything that happens inside our cells has a function, Laurence Hurst explores a study in @plosbiology.org showing that the high diversity of transcripts in mammals is down to the fact that accidents happen... 🧪 Paper: plos.io/3Pcs2e6 Primer: plos.io/47Go2J2
If you get your hands on a decent UV flashlight or other UV light source, try pointing it at a bruised banana.
You'll have the opportunity to observe a phenomenon called "blue halos of death" caused by cellular senescence & the breakdown of chlorophyll in the fruit peel.
Let's talk about it.
