Pancreatic ductal adenocarcinoma is notoriously resistant to current immunotherapies
Here, Leonidas C. Platanias & team show Slfn5 is a target & modulator of Type I IFN responses that promotes an immunosuppressive tumor microenvironment in models of PDAC: doi.org/10.1172/jci....
Posts by Leonidas Platanias, MD
This is awful. A young mother with young children who died from an aggressive form of leukemia. This is a reminder of how important medical research is. There will be a day that this leukemia will be curable. But only research can make this happen soon.
Check presentation today by the incredible H Foundation from the Goombay Bash event earlier this summer. Their incredible philanthropic support of basic science research at the Lurie Cancer Center has had major impact on our efforts. So grateful for their support!
“You can easily judge the character of a someone by how they treat those who can do nothing for them.”
Johann Wolfgang von Goethe (1749 - 1832)
At the Department of Biochemistry& Molecular Genetics annual holiday event with the greatest Chair of Biochemistry Ali Shilatifard & the incredible Feng Yue who just published a major article @nature.com
!
"I don't write music for critics. I write music for God."
Anton Bruckner (1824 - 1896)
www.youtube.com/watch?v=AUBD...
“Τι νέοι που φτάσαμεν εδώ, στο έρμο νησί, στο χείλος
του κόσμου, δώθε απ’ τ’ όνειρο και κείθε απ’ τη γη!”
Kostas Karyotakis (1896 - 1928)
With our amazing community advisory board of @luriecancer.bsky.social today!
Μέρα του Απρίλη
Πράσινο λάμπος,
γελούσε ο κάμπος
με το τριφύλλι.
Ως την εφίλει
το πρωινό θάμπος,
η φύση σάμπως
γλυκά να ομίλει.
Εκελαδούσαν
πουλιά, πετώντας όλο πιο πάνω.
Τ’ άνθη ευωδούσαν.
Κι είπε απορώντας: «Πώς να πεθάνω;»
Διάκος poem
Kostas Karyotakis (1896 -1928)
A woman, a man, and the start line for a race. There is a purple and white balloon arch, under which a banner reads “Cancer Survivors’ Walk.”
A man and a woman, haha, both wearing sunglasses.
People signing and photographing a white banner.
A crowd is gathered in front of a stage, all wearing various types of workout clothes. The Chicago skyline is in the distant background.
Happy National Cancer Survivors Day from Grant Park, site of the Lurie Cancer Center 32nd Annual Cancer Survivors’ Celebration Walk & 5K! #GoCats💜
Nice to finally meet you, @leonidasplatan1.bsky.social!
Great. I look forward to seeing you there!
The @luriecancer.bsky.social (LCC) went thru the competing renewal of NCI designation. For a 2nd time we got "exceptional" ranking. The NCI site visit team gave us a "perfect exceptional" (equivalent to 10). LCC is one of few in the nation and the only one in IL to ever achieve exceptional status.
One of the worst possible premieres of a symphony, was the premiere of Symphony #1 of Rachmaninoff in 1897.
It was conducted by Glazunov (a famous composer himself later) who was drunk at the time and was disastrous. Rachmaninoff suffered severe depression after that.
All the big breakthroughs in cancer have started with NIH and NCI funded research.
Every single medication or curative approach used in cancer patients is the direct or indirect result of NIH/NCI funded research.
Johanna Senfter (1879 - 1961) was a remarkable composer with amazing violin and piano works.
Her only recorded Symphony 4, has very strong Brucknerian influences and is absolutely stunning. But she has written 9 in total. Hard to understand why her work is being ignored.
The reason so many diseases are cured has been the investment of the USA to medical research via NIH support.
Without strong support for the NIH, important medical breakthroughs would have never happened. And drugs that cure or control diseases would have never existed.
“No, science is no illusion. But an illusion it would be to suppose that what science cannot give us we can get elsewhere”.
Sigmund Freud (1856 - 1939)
"A human being is a part of the whole, called by us "universe," a part limited in time and space."
Albert Einstein (1879 - 1955)
“The task is not so much to see what no one yet has seen, but to think what nobody yet has thought about that which everybody sees."
Arthur Schopenhauer (1788 - 1860)
Cancer mortality rates have been dropping because of NIH and NCI funded research to Universities. Without it there would be no new cancer treatments that save lives.
“Science is the highest personification of the nation because that nation will remain the first which carries the furthest the works of thought and intelligence.”
Louis Pasteur (1822 - 1895)
“Science is the highest personification of the nation because that nation will remain the first which carries the furthest the works of thought and intelligence.”
Louis Pasteur (1822 - 1895)
The impact of science and medicine in saving billions of lives can not be measured in dollars. Human life is priceless.
Since its discovery in 1882, over 1 billion people have died from tuberculosis, including great composers, like Chopin, Purcell, Lili Boulanger, Stravinsky.
One can only imagine how the world would be today if medical research had not found TB drugs.
Science is priceless.
"History shows us the life of nations and can find nothing to relate except wars and insurrections; the years of peace appear here and there only as short pauses, as intervals between the acts".
Arthur Schopenhauer (1788 - 1860)
“Everything I discovered was new and most of it was really valuable”.
Alice Hamilton (1869 - 1970)
Chicago
symphony 2. All his symphonies are great.