Using tumour avatars to optimise personalised medicine for cancer patients at University of St Andrews on FindAPhD.com PhD Project - Using tumour avatars to optimise personalised medicine for cancer patients at University of St Andrews, listed on FindAPhD.com

Join an excellent fully funded 4-year PhD opportunity using patient-derived organoids to improve cancer drug therapy. Apply now! 🎓🔬 #PhD #CancerResearch
www.findaphd.com/phds/project...

Scikit-bio: a fundamental Python library for biological omic data analysis www.nature.com/articles/s4...

How does messenger RNA (mRNA) get out of the nucleus to become a protein? Eukaryotic mRNA is packaged, exported, and then translated in the cytoplasm. But how do these steps work? And what are open questions? Check out our new review for our take: www.annualreviews.org/content/jour... (1/3)

Big news: we are setting up a new non-profit organization to run bioRxiv and medRxiv. It's called openRxiv [no it's not a new preprint server; it's dedicated organization to oversee the servers] openrxiv.org 1/n

New challenges Explore the challenges currently open for Expressions of Interest.

Great opportunity! Please do get in touch if teams are forming around 'Rewiring Cancer Cells' we can include our spatial transcriptomics, long read RNA sequencing, high throughput image analysis www.cancergrandchallenges.org/new-challeng...

For many genes, the RNA and protein levels change in opposite directions with age.

Yet, they correlate positively within an age group.
==> A clear example of Simpson's paradox, similar to what we described previously journals.plos.org/ploscompbiol...

Furthermore, ...

RNA language models predict mutations that improve RNA function Nature Communications - Generating RNA sequences with improved function remains challenging. Here, authors present an RNA database for RNA structural and functional analysis. They use this database...

New paper from @jhdcate.bsky.social lab: RNA language models identify mutations modulating ribosome function & stability. #RNABiology #Ribosome: rdcu.be/d2L7n

Appreciate if you can add to list 1

Happy to join

Pymportx: facilitating next-generation transcriptomics analysis in Python Abstract. The efficient importation of quantified gene expression data is pivotal in transcriptomics. Historically, the R package Tximport addressed this n

I am happy to see that both papers have been published. Pymportx is Python port of Tximport #bioinformatics academic.oup.com/nargab/artic...

I wasn't convinced of the first Xodus mainly due to the alternatives not being ready. While now, this platform is ripe and ready, also a big fan of decentralisation. I do hope past mistakes are not repeated and this becomes a place where great ideas flourish.

I would love to join!

Glad to be here!